Development Level

Tbio 12 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

increased circulating choleste... 2 | 66
abnormal embryo size 1 | 220
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased cardiac muscle contr... 1 | 11
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
increased aggression 1 | 4
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38

Disease

Atherosclerosis 16 | 291
Coronary artery disease 14 | 268
Lipid metabolism disorder 13 | 114
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
diabetes mellitus 11 | 1,728
Carcinoma 9 | 11,493
ovarian cancer 9 | 8,520
Hypercholesterolemia, Familial 8 | 23
Hyperlipoproteinemia Type II 7 | 12
Obesity 7 | 678
psoriasis 7 | 6,694
Cardiovascular system disease 6 | 246
Kidney disease 6 | 430
glioblastoma 6 | 5,792
invasive ductal carcinoma 6 | 2,951
malignant mesothelioma 6 | 3,232
osteosarcoma 6 | 7,950
Autosomal recessive predisposition 5 | 1,442
Hyperlipidemia 5 | 43
Hypertriglyceridemia result 5 | 37
acute quadriplegic myopathy 5 | 1,158
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 4,104
medulloblastoma, large-cell 5 | 6,241
oligodendroglioma 5 | 2,850
Age related macular degeneration 4 | 72
Amyloidosis 4 | 67
Astrocytoma, Pilocytic 4 | 3,081
Hepatomegaly 4 | 285
High density lipoprotein decreased 4 | 10
Hypercholesterolemia 4 | 44
Hypertension 4 | 396
Hypoalphalipoproteinemias 4 | 10
Schizophrenia 4 | 1,160
Splenomegaly 4 | 190
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
atypical teratoid / rhabdoid tumor 4 | 5,112
cystic fibrosis 4 | 1,696
juvenile dermatomyositis 4 | 1,187
lung cancer 4 | 4,740
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 658
Anemia 3 | 365
Arcus Senilis 3 | 11
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Cardiovascular Diseases 3 | 59
Cerebrovascular disease 3 | 238
Chemical and Drug Induced Liver Injury 3 | 195
Cholesteryl Ester Transfer Protein Deficiency 3 | 3
Clouding of corneal stroma 3 | 50
Colorectal Neoplasms 3 | 243
Corneal Opacity 3 | 53
Down syndrome 3 | 499
Drug Eruptions 3 | 18
Hypercholesterolemia, Autosomal Dominant, Type B 3 | 5
Hyperlipidemias 3 | 17
Hyperlipoproteinemia Type IIa 3 | 11
Hyperlipoproteinemias 3 | 5
Hypertensive disease 3 | 292
Kidney Failure 3 | 111
Kidney Failure, Chronic 3 | 46
Kidney cancer 3 | 2,613
Lung Neoplasms 3 | 232
Macular degeneration 3 | 65
Metabolic syndrome X 3 | 52
Pediatric Obesity 3 | 4
Proteinuria 3 | 144
Serum cholesterol raised 3 | 22
Type 2 diabetes mellitus 3 | 272
Vascular disease 3 | 319
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478
ependymoma 3 | 4,679
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
nephrosclerosis 3 | 333
pancreatic cancer 3 | 2,398
Alzheimer Disease 2 | 83
Atopic dermatitis 2 | 952
Dementia 2 | 175
Electromyogram abnormal 2 | 49
Heart disease 2 | 306
Hemoglobin low 2 | 124
Liver Cirrhosis, Experimental 2 | 769
Pick disease 2 | 1,894
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Seizures 2 | 596
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
dermatomyositis 2 | 966
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
tuberculosis 2 | 2,010

Tissue

Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Skin and soft tissues 17 | 17,230
Blood and immune system 16 | 16,909
Male tissues 16 | 17,142
Urinary Tract 16 | 16,678
Respiratory system 15 | 16,393
Nervous System 14 | 16,725
Cardiovascular System 13 | 15,192

Target Family

Non-IDG 11 | 12,091
Enzyme 3 | 4,145
Transporter 3 | 473

GO Process

reverse cholesterol transport 17 | 17
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 5 ABCA5 Tbio Transporter -1.09683 13.2 131
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.58826 425.0 481
ATP-binding cassette sub-family G member 1 ABCG1 Tbio Transporter -2.52701 319.9 260
Cholesteryl ester transfer protein CETP Tchem Non-IDG -3.20658 1755.9 264
Phosphatidylcholine-sterol acyltransferase LCAT Tbio Enzyme -2.52851 336.6 270
Endothelial lipase LIPG Tchem Enzyme -2.28530 192.2 712
Hepatic triacylglycerol lipase LIPC Tchem Enzyme -2.56840 389.0 258
Apolipoprotein C-III APOC3 Tbio Non-IDG -2.93348 875.2 267
Apolipoprotein C-II APOC2 Tbio Non-IDG -2.51086 342.7 22