Development Level

Tbio 63 | 11,178
Tdark 10 | 6,569
Tchem 8 | 1,885

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 17 | 979
embryonic lethality prior to t... 6 | 278
embryonic lethality prior to o... 4 | 239
abnormal embryo size 3 | 220
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
increased fasted circulating g... 2 | 76
increased grip strength 2 | 41
prenatal lethality prior to he... 2 | 87
abnormal bone structure 1 | 187
abnormal kidney morphology 1 | 65
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
absent pinna reflex 1 | 23
cyanosis 1 | 7
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
edema 1 | 59
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
long tibia 1 | 25
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
thrombocytosis 1 | 27

Disease

ovarian cancer 51 | 8,297
Carcinoma 49 | 11,192
osteosarcoma 40 | 7,766
glioblastoma 37 | 5,635
medulloblastoma, large-cell 30 | 6,086
psoriasis 28 | 6,514
atypical teratoid / rhabdoid tumor 27 | 4,971
lung cancer 26 | 4,607
ependymoma 25 | 4,559
adult high grade glioma 23 | 3,701
group 3 medulloblastoma 23 | 4,002
Breast cancer 19 | 3,469
lung adenocarcinoma 17 | 2,627
malignant mesothelioma 17 | 3,135
primitive neuroectodermal tumor 17 | 2,957
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,204
non-small cell lung cancer 16 | 2,799
Multiple myeloma 15 | 1,296
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,902
invasive ductal carcinoma 15 | 2,867
oligodendroglioma 14 | 2,768
dermatomyositis 13 | 941
Astrocytoma, Pilocytic 12 | 3,006
adrenocortical carcinoma 12 | 1,385
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,872
Atopic dermatitis 11 | 915
breast carcinoma 11 | 1,589
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,911
Kidney cancer 10 | 2,548
lung carcinoma 10 | 2,755
non primary Sjogren syndrome sicca 10 | 861
pancreatic cancer 10 | 2,322
pituitary cancer 10 | 1,915
astrocytoma 9 | 1,113
colon cancer 9 | 1,428
diabetes mellitus 9 | 1,683
ductal carcinoma in situ 9 | 1,686
juvenile dermatomyositis 9 | 1,147
Pick disease 8 | 1,856
astrocytic glioma 8 | 2,530
pediatric high grade glioma 8 | 1,035
Cancer 7 | 2,388
Endometriosis 7 | 521
acute quadriplegic myopathy 7 | 1,133
Neurodegenerative disease 6 | 402
active Crohn's disease 6 | 882
nasopharyngeal carcinoma 6 | 1,024
pancreatic carcinoma 6 | 555
spina bifida 6 | 1,053
Autosomal recessive predisposition 5 | 1,407
Epilepsy 5 | 775
esophageal adenocarcinoma 5 | 696
group 4 medulloblastoma 5 | 1,806
subependymal giant cell astrocytoma 5 | 2,230
tuberculosis and treatment for 6 months 5 | 399
Alzheimer's disease 4 | 640
Duchenne muscular dystrophy 4 | 587
Intellectual disability 4 | 998
Liver cancer 4 | 589
Menkes disease 4 | 19
Rheumatoid arthritis 4 | 1,156
Schizophrenia 4 | 1,136
Seizures 4 | 584
acute myeloid leukemia 4 | 760
cystic fibrosis 4 | 1,629
interstitial cystitis 4 | 2,237
primary Sjogren syndrome 4 | 710
Amyotrophic lateral sclerosis 3 | 437
Endometrial cancer 3 | 301
Hyperreflexia 3 | 208
Legionnaires' disease 3 | 20
Microcephaly 3 | 166
Paraplegia 3 | 72
Parkinson's disease 3 | 378
Short stature 3 | 514
Small head 3 | 366
active ulcerative colitis 3 | 736
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 492
gastric cancer 3 | 445
hepatocellular carcinoma 3 | 536
hereditary spastic paraplegia 3 | 313
tuberculosis 3 | 1,963
tuberculosis and treatment for 3 months 3 | 175
Acquired scoliosis 2 | 274
Anteverted nostril 2 | 186
Bipolar Disorder 2 | 646
Congenital Epicanthus 2 | 175
Curvature of spine 2 | 275
Cutis Laxa 2 | 39
Depressed nasal bridge 2 | 191
Long philtrum 2 | 137
Micromelia 2 | 58
Myocardial Ischemia 2 | 162
Polycystic ovary syndrome 2 | 348
Prostatic Neoplasms 2 | 472
Waldenstrons macroglobulinemia 2 | 742
aldosterone-producing adenoma 2 | 646
chronic rhinosinusitis 2 | 505
primary pancreatic ductal adenocarcinoma 2 | 1,071
sonic hedgehog group medulloblastoma 2 | 459

Tissue

Endocrine System 81 | 18,159
Blood and immune system 79 | 16,909
Digestive Tract 79 | 17,369
Female tissues 79 | 17,400
Male tissues 79 | 17,142
Nervous System 79 | 16,725
Skin and soft tissues 79 | 17,230
Urinary Tract 79 | 16,678
Liver and Pancreas 78 | 16,750
Respiratory system 78 | 16,393
Cardiovascular System 77 | 15,192

Target Family

Non-IDG 64 | 12,091
Enzyme 14 | 4,145
Transporter 2 | 473
Kinase 1 | 634

GO Process

retrograde vesicle-mediated tr... 81 | 81
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-6A RAB6A Tbio Enzyme -2.09488 134.5 207
ADP-ribosylation factor 4 ARF4 Tbio Enzyme -1.67012 46.6 163
Neuroblastoma-amplified sequence NBAS Tbio Non-IDG -2.10077 121.7 37
Chromosome-associated kinesin KIF4A KIF4A Tchem Non-IDG -1.91717 78.0 157
ADP-ribosylation factor GTPase-activating protein 3 ARFGAP3 Tbio Enzyme -1.32293 23.8 204
Centromere-associated protein E CENPE Tchem Non-IDG -2.14817 140.2 166
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91664 86.4 148
Kinesin-like protein KIF15 KIF15 Tbio Non-IDG -1.54905 30.3 145
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.50460 33.8 170