Development Level

Tbio 59 | 10,625
Tdark 11 | 7,003
Tchem 8 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 12 | 633
embryonic lethality prior to t... 6 | 187
embryonic lethality prior to o... 3 | 148
abnormal embryo size 2 | 112
decreased circulating glucose ... 2 | 121
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal testis morphology 1 | 30
absent pinna reflex 1 | 21
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased red blood cell distr... 1 | 11
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
embryonic growth retardation 1 | 28
hydrops fetalis 1 | 22
hyperactivity 1 | 108
immune system phenotype 1 | 17
impaired glucose tolerance 1 | 52
increased bone mineral content 1 | 92
increased circulating bilirubi... 1 | 16
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
increased vertical activity 1 | 18
prenatal lethality prior to he... 1 | 64
small testis 1 | 37
straub tail 1 | 26
thrombocytosis 1 | 23

Disease

ovarian cancer 48 | 8,484
osteosarcoma 38 | 7,933
glioblastoma 37 | 5,572
medulloblastoma, large-cell 29 | 6,234
psoriasis 26 | 6,685
atypical teratoid / rhabdoid tumor 25 | 4,369
lung cancer 24 | 4,466
pediatric high grade glioma 23 | 2,712
lung adenocarcinoma 17 | 2,713
primitive neuroectodermal tumor 17 | 3,031
malignant mesothelioma 16 | 3,162
non-small cell lung cancer 16 | 2,798
Breast cancer 15 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
invasive ductal carcinoma 15 | 2,950
Multiple myeloma 14 | 1,327
oligodendroglioma 14 | 2,849
pilocytic astrocytoma 13 | 3,086
adrenocortical carcinoma 12 | 1,427
dermatomyositis 12 | 933
ependymoma 12 | 2,514
Atopic dermatitis 11 | 944
breast carcinoma 11 | 1,614
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
group 3 medulloblastoma 10 | 2,254
lung carcinoma 10 | 2,844
non primary Sjogren syndrome sicca 10 | 840
pituitary cancer 10 | 1,972
posterior fossa group B ependymoma 10 | 1,530
sonic hedgehog group medulloblastoma 10 | 1,482
Carcinoma 9 | 2,147
IGA Glomerulonephritis 9 | 454
astrocytoma 9 | 1,493
colon cancer 9 | 1,475
diabetes mellitus 9 | 1,663
ductal carcinoma in situ 9 | 1,745
juvenile dermatomyositis 9 | 1,189
pancreatic cancer 9 | 2,300
Pick disease 8 | 1,893
adult high grade glioma 8 | 2,148
tuberculosis and treatment for 6 months 8 | 686
Endometriosis 7 | 535
acute quadriplegic myopathy 7 | 1,157
Cancer 6 | 2,346
active Crohn's disease 6 | 918
astrocytic glioma 6 | 2,241
group 4 medulloblastoma 6 | 1,875
medulloblastoma 6 | 1,524
nasopharyngeal carcinoma 6 | 1,056
posterior fossa group A ependymoma 6 | 1,511
Neurodegenerative disease 5 | 383
pancreatic carcinoma 5 | 567
subependymal giant cell astrocytoma 5 | 2,287
Duchenne muscular dystrophy 4 | 602
Menkes disease 4 | 20
Rheumatoid Arthritis 4 | 1,160
cystic fibrosis 4 | 1,665
esophageal adenocarcinoma 4 | 737
inflammatory breast cancer 4 | 404
interstitial cystitis 4 | 2,299
primary Sjogren syndrome 4 | 789
spina bifida 4 | 1,064
Alzheimer's disease 3 | 644
Legionnaires' disease 3 | 20
Microcephaly 3 | 149
Oculocerebrorenal syndrome 3 | 23
Parkinson's disease 3 | 364
active ulcerative colitis 3 | 477
acute myeloid leukemia 3 | 780
atypical teratoid/rhabdoid tumor 3 | 1,095
hereditary spastic paraplegia 3 | 313
Amyotrophic Lateral Sclerosis 2 | 431
Barrett's esophagus 2 | 183
Benign glioma 2 | 2
COPD 2 | 113
Congenital disorder of glycosylation 2 | 53
Disease Progression 2 | 125
Malaria 2 | 140
Myocardial Ischemia 2 | 169
Neuropathy 2 | 210
Paraplegia 2 | 71
Polycystic Ovary Syndrome 2 | 332
Polycystic kidney disease 2 | 54
Prostatic Neoplasms 2 | 471
Schizophrenia 2 | 501
Seckel syndrome 2 | 34
Stomach Neoplasms 2 | 282
Tetanus 2 | 66
Wilson disease 2 | 16
aldosterone-producing adenoma 2 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,056
cystic fibrosis and chronic rhinosinusitis 2 | 213
gastric cancer 2 | 430
hepatocellular carcinoma 2 | 532
primary pancreatic ductal adenocarcinoma 2 | 1,271
tuberculosis 2 | 1,557

Tissue

Blood and immune system 78 | 17,995
Cardiovascular System 78 | 17,958
Digestive Tract 78 | 18,473
Endocrine System 78 | 18,512
Female tissues 78 | 18,647
Liver and Pancreas 78 | 18,136
Male tissues 78 | 17,969
Nervous System 78 | 18,561
Urinary Tract 78 | 18,444
Respiratory system 77 | 17,484
Skin and soft tissues 77 | 18,115

Target Family

Non-IDG 61 | 11,971
Enzyme 14 | 4,146
Transporter 2 | 473
Kinase 1 | 634

GO Process

retrograde vesicle-mediated tr... 78 | 78
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable phospholipid-transporting ATPase IIB ATP9B Tdark Transporter -0.57248 3.74 5
Kinesin-like protein KIF1C KIF1C Tbio Non-IDG -1.21884 20.0 95
Vesicular integral-membrane protein VIP36 LMAN2 Tbio Non-IDG -1.35463 24.9 101
Transmembrane emp24 domain-containing protein 9 TMED9 Tdark Non-IDG -0.05436 0.58 101
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.33400 20.0 84
Tapasin TAPBP Tbio Non-IDG -2.50535 373.6 134
ER lumen protein-retaining receptor 1 KDELR1 Tbio Non-IDG -2.24993 170.8 122
Protein RER1 RER1 Tbio Non-IDG -1.53342 36.4 50
Surfeit locus protein 4 SURF4 Tbio Non-IDG -1.19013 16.6 84
Ras-related protein Rab-1B RAB1B Tbio Enzyme 36.3 104