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Development Level

Tbio 44 | 10,625
Tchem 7 | 1,890
Tclin 6 | 602

IMPC Term

preweaning lethality, complete... 5 | 633
decreased body weight 3 | 174
abnormal whole-body plethysmog... 2 | 4
decreased body temperature 2 | 2
decreased circulating triglyce... 2 | 83
decreased lumbar vertebrae num... 2 | 62
hyperactivity 2 | 108
increased blood urea nitrogen ... 2 | 44
abnormal behavior 1 | 226
abnormal forced expiratory flo... 1 | 1
abnormal placenta size 1 | 10
abnormal skin coloration 1 | 18
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal vocalization 1 | 21
altered righting response 1 | 1
cataract 1 | 26
decreased body length 1 | 108
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating amylase ... 1 | 24
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased lean body mass 1 | 195
decreased prepulse inhibition 1 | 52
decreased tidal volume 1 | 1
edema 1 | 11
enlarged heart 1 | 111
enlarged uterus 1 | 3
hemorrhage 1 | 12
hydrometra 1 | 13
hypoactivity 1 | 89
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased NK T cell number 1 | 11
increased blood uric acid leve... 1 | 5
increased body weight 1 | 42
increased cellular hemoglobin ... 1 | 2
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating potassiu... 1 | 31
increased circulating total pr... 1 | 20
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
macrophthalmia 1 | 2
male infertility 1 | 62
mydriasis 1 | 9
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
small superior vagus ganglion 1 | 20
small testis 1 | 37
thrombocytopenia 1 | 46

Disease

medulloblastoma, large-cell 26 | 6,234
psoriasis 25 | 6,685
osteosarcoma 24 | 7,933
ovarian cancer 22 | 8,492
glioblastoma 19 | 5,572
Retinitis pigmentosa 16 | 156
group 3 medulloblastoma 16 | 2,254
lung cancer 13 | 4,473
oligodendroglioma 13 | 2,849
Carcinoma 12 | 2,147
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,289
primitive neuroectodermal tumor 12 | 3,031
Breast cancer 11 | 3,099
ependymoma 11 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
pediatric high grade glioma 11 | 2,712
pilocytic astrocytoma 11 | 3,086
Cancer 10 | 2,346
Fundus dystrophy 10 | 77
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
Pick disease 9 | 1,893
astrocytic glioma 9 | 2,241
astrocytoma 9 | 1,493
atypical teratoid / rhabdoid tumor 9 | 4,369
atypical teratoid/rhabdoid tumor 9 | 1,095
invasive ductal carcinoma 9 | 2,950
pancreatic cancer 9 | 2,300
posterior fossa group A ependymoma 9 | 1,511
posterior fossa group B ependymoma 9 | 1,530
Leber congenital amaurosis 8 | 72
group 4 medulloblastoma 8 | 1,875
malignant mesothelioma 8 | 3,163
pituitary cancer 8 | 1,972
sonic hedgehog group medulloblastoma 8 | 1,482
subependymal giant cell astrocytoma 8 | 2,287
adrenocortical carcinoma 7 | 1,427
diabetes mellitus 7 | 1,663
lung adenocarcinoma 7 | 2,714
tuberculosis 7 | 1,563
Cone dystrophy 6 | 59
Night Blindness 6 | 39
cone-rod dystrophy 6 | 60
juvenile dermatomyositis 6 | 1,189
lung carcinoma 6 | 2,844
non-small cell lung cancer 6 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
Alzheimer's disease 5 | 644
Blindness 5 | 84
Peripheral Neuropathy 5 | 303
Prostatic Neoplasms 5 | 471
breast carcinoma 5 | 1,614
cystic fibrosis 5 | 1,670
primary pancreatic ductal adenocarcinoma 5 | 1,271
ulcerative colitis 5 | 2,087
Congenital stationary night blindness 4 | 28
Craniofacial Abnormalities 4 | 147
Glaucoma 4 | 135
Nephronophthisis 4 | 74
Night blindness, congenital stationary 4 | 14
Retinal Degeneration 4 | 49
Rheumatoid Arthritis 4 | 1,171
acute quadriplegic myopathy 4 | 1,157
adult high grade glioma 4 | 2,148
colon cancer 4 | 1,475
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 832
nasopharyngeal carcinoma 4 | 1,056
non primary Sjogren syndrome sicca 4 | 840
Autistic Disorder 3 | 320
Coloboma 3 | 52
Duchenne muscular dystrophy 3 | 602
Endometriosis 3 | 535
Fundus Albipunctatus 3 | 8
Intellectual disability 3 | 573
Mammary Neoplasms 3 | 410
Microphthalmia 3 | 79
Myopia 3 | 99
Parkinson's disease 3 | 364
Renal Cell Carcinoma 3 | 199
Senior-Loken syndrome 3 | 22
Uveitis 3 | 103
active Crohn's disease 3 | 918
acute myeloid leukemia 3 | 785
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,056
dermatomyositis 3 | 967
ductal carcinoma in situ 3 | 1,745
head and neck cancer 3 | 270
interstitial cystitis 3 | 2,299
medulloblastoma 3 | 1,524
non-small cell lung carcinoma 3 | 413
Atopic dermatitis 2 | 944
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
Down syndrome 2 | 548
Hypersensitivity reaction type II disease 2 | 235
Waldenstrons macroglobulinemia 2 | 765
fibroadenoma 2 | 557
progressive supranuclear palsy 2 | 674
spina bifida 2 | 1,064

Tissue

Nervous System 56 | 18,561
Digestive Tract 55 | 18,473
Female tissues 55 | 18,647
Male tissues 55 | 17,969
Blood and immune system 54 | 17,995
Cardiovascular System 54 | 17,958
Endocrine System 54 | 18,512
Liver and Pancreas 54 | 18,136
Respiratory system 54 | 17,484
Urinary Tract 54 | 18,444
Skin and soft tissues 53 | 18,115

Target Family

Non-IDG 23 | 11,969
Transcription Factor 12 | 1,400
Enzyme 10 | 4,146
Kinase 4 | 634
Nuclear Receptor 3 | 48
GPCR 2 | 408
Epigenetic 1 | 242
Ion Channel 1 | 341
Transporter 1 | 473

GO Process

retina development in camera-t... 57 | 57
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
POU domain, class 4, transcription factor 2 POU4F2 Tbio Transcription Factor -1.92525 86.9 136
Membrane frizzled-related protein MFRP Tbio Non-IDG -2.03056 58.2 162
Photoreceptor-specific nuclear receptor NR2E3 Tchem Nuclear Receptor 0.00000 223
Laminin subunit gamma-3 LAMC3 Tbio Non-IDG -1.36132 20.6 68
Nuclear receptor subfamily 2 group E member 1 NR2E1 Tchem Nuclear Receptor -1.63099 44.2 203
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.14190 1375.5 488
Tyrosine-protein kinase Mer MERTK Tchem Kinase -2.22327 172.9 511
Tubulin polyglutamylase TTLL5 TTLL5 Tbio Enzyme -0.67048 4.98 20
Ventral anterior homeobox 2 VAX2 Tbio Transcription Factor -1.08177 13.4 81
Chloride channel protein 2 CLCN2 Tclin Ion Channel -2.01977 99.4 191