Development Level

Tbio 34 | 11,445
Tchem 25 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 5 | 499
abnormal bone structure 3 | 187
abnormal embryo size 2 | 220
decreased bone mineral density 2 | 126
decreased mean corpuscular vol... 2 | 79
increased mean corpuscular vol... 2 | 92
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal embryo turning 1 | 31
absent startle reflex 1 | 24
decreased bone mineral content 1 | 151
decreased circulating sodium l... 1 | 22
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased caudal vertebrae num... 1 | 7
increased mean corpuscular hem... 1 | 96
sclerocornea 1 | 2
tremors 1 | 39

Disease

Carcinoma 38 | 11,493
Cancer 37 | 2,499
glioblastoma 37 | 5,792
atypical teratoid / rhabdoid tumor 34 | 5,112
ovarian cancer 33 | 8,520
lung cancer 31 | 4,740
Astrocytoma, Pilocytic 29 | 3,081
ependymoma 29 | 4,679
osteosarcoma 29 | 7,950
medulloblastoma, large-cell 28 | 6,241
psoriasis 28 | 6,694
lung carcinoma 26 | 2,843
Breast cancer 24 | 3,578
adult high grade glioma 24 | 3,801
group 3 medulloblastoma 23 | 4,104
interstitial cystitis 22 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
oligodendroglioma 22 | 2,850
lung adenocarcinoma 21 | 2,716
malignant mesothelioma 21 | 3,232
non-small cell lung cancer 21 | 2,890
pancreatic cancer 21 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
invasive ductal carcinoma 20 | 2,951
Schizophrenia 18 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
astrocytic glioma 17 | 2,597
pituitary cancer 17 | 1,972
primitive neuroectodermal tumor 16 | 3,035
cystic fibrosis 15 | 1,696
diabetes mellitus 15 | 1,728
adrenocortical carcinoma 14 | 1,428
primary pancreatic ductal adenocarcinoma 14 | 1,109
Pick disease 13 | 1,894
subependymal giant cell astrocytoma 12 | 2,287
tuberculosis 12 | 2,010
Atherosclerosis 11 | 291
Cerebrovascular disease 11 | 238
Kidney cancer 11 | 2,613
Rheumatoid arthritis 11 | 1,191
breast carcinoma 11 | 1,638
ulcerative colitis 11 | 1,819
Alzheimer's disease 10 | 658
ductal carcinoma in situ 10 | 1,745
gastric carcinoma 10 | 807
group 4 medulloblastoma 10 | 1,855
Autosomal recessive predisposition 9 | 1,442
Bipolar Disorder 9 | 666
Epilepsy 9 | 792
Hypertension 9 | 396
Kidney disease 9 | 430
Liver Cirrhosis, Experimental 9 | 769
Prostatic Neoplasms 9 | 495
Toxic encephalopathy 9 | 141
cutaneous lupus erythematosus 9 | 1,057
juvenile dermatomyositis 9 | 1,187
nasopharyngeal carcinoma 9 | 1,058
pediatric high grade glioma 9 | 1,064
Coronary artery disease 8 | 268
Depressive disorder 8 | 409
Down syndrome 8 | 499
Hypertensive disease 8 | 292
Pulmonary Fibrosis 8 | 106
Seizures 8 | 596
colon cancer 8 | 1,478
Breast Neoplasms 7 | 445
Carcinoma, Hepatocellular 7 | 228
Endometriosis 7 | 540
Glaucoma 7 | 239
Liver carcinoma 7 | 240
Mammary Neoplasms 7 | 425
Melanoma 7 | 711
Multiple Sclerosis 7 | 540
Neurodegenerative disease 7 | 414
Obesity 7 | 678
Parkinson's disease 7 | 392
active ulcerative colitis 7 | 764
esophageal adenocarcinoma 7 | 737
Arthritis 6 | 290
Asthma 6 | 385
Atopic dermatitis 6 | 952
Cognitive delay 6 | 608
Dementia 6 | 175
Global developmental delay 6 | 608
Liver Cirrhosis 6 | 181
Liver disease 6 | 237
Mental and motor retardation 6 | 608
Multiple myeloma 6 | 1,332
Neoplasm Invasiveness 6 | 161
Pneumonia 6 | 174
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Duchenne muscular dystrophy 5 | 601
Mental Depression 5 | 333
fibroadenoma 5 | 559
hepatocellular carcinoma 5 | 547
nephrosclerosis 5 | 333
non diabetic and post-ischemic heart failure 5 | 200
primary Sjogren syndrome 5 | 735
spina bifida 5 | 1,074

Tissue

Digestive Tract 65 | 17,369
Endocrine System 65 | 18,159
Liver and Pancreas 65 | 16,750
Blood and immune system 63 | 16,909
Female tissues 63 | 17,400
Male tissues 63 | 17,142
Skin and soft tissues 63 | 17,230
Urinary Tract 63 | 16,678
Nervous System 62 | 16,725
Respiratory system 60 | 16,393
Cardiovascular System 56 | 15,192

Target Family

Non-IDG 30 | 12,091
Enzyme 10 | 4,145
Transcription Factor 8 | 1,400
GPCR 7 | 408
Kinase 4 | 634
Ion Channel 3 | 344
Transporter 2 | 473
Epigenetic 1 | 242

GO Process

response to wounding 65 | 65
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteinase-activated receptor 4 F2RL3 Tchem GPCR -1.50044 34.1 276
Plasmolipin PLLP Tbio Ion Channel -1.58286 39.3 74
Transmembrane domain-containing protein TMIGD3 TMIGD3 Tchem Non-IDG 0.00000 104
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Extracellular sulfatase Sulf-2 SULF2 Tbio Enzyme -1.74398 67.0 221
Nucleosome-remodeling factor subunit BPTF BPTF Tchem Epigenetic -1.77472 58.0 68
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
Neuromodulin GAP43 Tbio Non-IDG -2.93905 762.9 597
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
mRNA decay activator protein ZFP36L1 ZFP36L1 Tbio Non-IDG -1.51339 38.6 285