Development Level

Tbio 79 | 11,651
Tchem 15 | 1,388
Tclin 9 | 612
Tdark 4 | 6,593

IMPC Phenotype

preweaning lethality, incomple... 7 | 499
embryonic lethality prior to o... 6 | 239
preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 4 | 278
abnormal behavior 3 | 298
abnormal heart morphology 2 | 162
increased lean body mass 2 | 172
increased neutrophil cell numb... 2 | 46
short tibia 2 | 97
small superior vagus ganglion 2 | 74
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating glucose ... 1 | 126
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
hemorrhage 1 | 23
hydrometra 1 | 53
increased aggression 1 | 4
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
pale yolk sac 1 | 25
pallor 1 | 34
shortened RR interval 1 | 17
small adrenal glands 1 | 16
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 66 | 11,493
psoriasis 64 | 6,694
ovarian cancer 63 | 8,520
lung cancer 57 | 4,740
Cancer 54 | 2,499
glioblastoma 47 | 5,792
pancreatic cancer 41 | 2,398
medulloblastoma, large-cell 40 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
osteosarcoma 38 | 7,950
cutaneous lupus erythematosus 37 | 1,057
Breast cancer 35 | 3,578
malignant mesothelioma 35 | 3,232
juvenile dermatomyositis 34 | 1,187
lung carcinoma 34 | 2,843
cystic fibrosis 33 | 1,696
Multiple Sclerosis 32 | 540
interstitial cystitis 32 | 2,312
ependymoma 31 | 4,679
invasive ductal carcinoma 29 | 2,951
tuberculosis 29 | 2,010
Influenza 27 | 142
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
Astrocytoma, Pilocytic 26 | 3,081
atypical teratoid / rhabdoid tumor 26 | 5,112
dermatomyositis 25 | 966
lung adenocarcinoma 25 | 2,716
primary Sjogren syndrome 24 | 735
adult high grade glioma 22 | 3,801
ulcerative colitis 22 | 1,819
diabetes mellitus 21 | 1,728
nasopharyngeal carcinoma 20 | 1,058
pituitary cancer 20 | 1,972
subependymal giant cell astrocytoma 20 | 2,287
Influenza, Human 19 | 51
Systemic lupus erythematosus 19 | 194
non-small cell lung cancer 19 | 2,890
Kidney cancer 18 | 2,613
Multiple myeloma 18 | 1,332
group 3 medulloblastoma 18 | 4,104
active Crohn's disease 17 | 922
Autosomal recessive predisposition 16 | 1,442
breast carcinoma 16 | 1,638
Atopic dermatitis 15 | 952
Breast Neoplasms 15 | 445
Microphthalmia with limb anomalies 15 | 40
Rheumatoid arthritis 15 | 1,191
astrocytoma 15 | 1,146
colon cancer 15 | 1,478
group 4 medulloblastoma 15 | 1,855
Asthma 14 | 385
Mammary Neoplasms 14 | 425
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
ductal carcinoma in situ 13 | 1,745
primary pancreatic ductal adenocarcinoma 13 | 1,109
Arthritis 12 | 290
Atherosclerosis 12 | 291
Hypersensitivity reaction type II disease 12 | 253
esophageal adenocarcinoma 12 | 737
Duchenne muscular dystrophy 11 | 601
Schizophrenia 11 | 1,160
acute quadriplegic myopathy 11 | 1,158
hepatocellular carcinoma 11 | 547
oligodendroglioma 11 | 2,850
primitive neuroectodermal tumor 11 | 3,035
Allergic hypersensitivity disease 10 | 126
Hepatitis C 10 | 94
Liver Cirrhosis, Experimental 10 | 769
Melanoma 10 | 711
Pick disease 10 | 1,894
active ulcerative colitis 10 | 764
pancreatic carcinoma 10 | 562
Arthritis, Rheumatoid 9 | 174
Dermatitis 9 | 157
Down syndrome 9 | 499
Hepatitis B 9 | 108
Intellectual disability 9 | 1,016
Kidney disease 9 | 430
pediatric high grade glioma 9 | 1,064
Allergic rhinitis 8 | 95
Bipolar Disorder 8 | 666
Hypereosinophilic syndrome 8 | 71
Inflammation 8 | 120
Neoplasm Invasiveness 8 | 161
Pneumonia 8 | 174
acute myeloid leukemia 8 | 783
adrenocortical carcinoma 8 | 1,428
mucosa-associated lymphoid tissue lymphoma 8 | 484
Alzheimer's disease 7 | 658
Dull intelligence 7 | 645
Endometriosis 7 | 540
Low intelligence 7 | 645
Malaria 7 | 160
Mental deficiency 7 | 645
Poor school performance 7 | 645
Prostatic Neoplasms 7 | 495
Type 2 diabetes mellitus 7 | 272
Waldenstrons macroglobulinemia 7 | 765
astrocytic glioma 7 | 2,597

Tissue

Blood and immune system 103 | 16,909
Skin and soft tissues 103 | 17,230
Endocrine System 102 | 18,159
Digestive Tract 101 | 17,369
Female tissues 101 | 17,400
Male tissues 101 | 17,142
Urinary Tract 101 | 16,678
Liver and Pancreas 100 | 16,750
Respiratory system 99 | 16,393
Nervous System 98 | 16,725
Cardiovascular System 97 | 15,192

Target Family

Non-IDG 59 | 12,091
Enzyme 24 | 4,145
Kinase 13 | 634
Transcription Factor 9 | 1,400
GPCR 2 | 408

GO Process

response to virus 107 | 107
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual oxidase 2 DUOX2 Tbio Enzyme -2.45061 251.8 126
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Interferon gamma receptor 1 IFNGR1 Tbio Non-IDG -2.23009 172.7 518
Radical S-adenosyl methionine domain-containing protein 2 RSAD2 Tbio Non-IDG -1.99883 103.3 117
Interleukin-1 receptor-associated kinase 3 IRAK3 Tchem Kinase -1.86631 84.0 427
C-C motif chemokine 19 CCL19 Tbio Non-IDG -2.45693 253.7 310
Interferon-induced transmembrane protein 1 IFITM1 Tbio Non-IDG -2.17051 130.0 283
Cytochrome P450 1A1 CYP1A1 Tchem Non-IDG -3.54987 3641.5 384
Cyclin-dependent kinase 6 CDK6 Tclin Kinase -2.71197 390.1 730
Hyaluronidase-1 HYAL1 Tbio Enzyme -1.88328 77.3 220