Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal locomotor behavior 1 | 24
hyperactivity 1 | 148
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Breast cancer 5 | 3,578
Carcinoma 5 | 11,493
ovarian cancer 5 | 8,520
pancreatic cancer 5 | 2,398
Cancer 4 | 2,499
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
Epilepsy 3 | 792
Kidney cancer 3 | 2,613
Seizures 3 | 596
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
subependymal giant cell astrocytoma 3 | 2,287
Adenoma 2 | 167
Anemia 2 | 365
Astrocytoma, Pilocytic 2 | 3,081
Cholecystitis 2 | 18
Endometrial cancer 2 | 311
Epistaxis 2 | 43
Hemangioma, Cavernous 2 | 20
Hematochezia 2 | 9
Hemoglobin low 2 | 124
Hereditary hemorrhagic telangiectasia 2 | 13
Hypertension, Portal 2 | 22
Intermittent migraine headaches 2 | 68
Iron-Refractory Iron Deficiency Anemia 2 | 15
Juvenile polyposis syndrome 2 | 7
Liver cancer 2 | 604
Migraine Disorders 2 | 76
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Skin cancer 2 | 469
Spontaneous haematoma 2 | 8
Stomach Neoplasms 2 | 300
Telangiectasia of the skin 2 | 39
Telangiectasis 2 | 36
Visceral angiomatosis 2 | 13
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group A ependymoma 2 | 468
psoriasis 2 | 6,694
ulcerative colitis 2 | 1,819
Angiofibroma 1 | 7
Bannayan-Riley-Ruvalcaba syndrome 1 | 8
Carcinoma of lung 1 | 3
Carcinoma of pancreas 1 | 5
Carcinoma, Ductal, Breast 1 | 11
Carney complex 1 | 25
Cone-shaped epiphyses 1 | 24
Decreased circulating ACTH level 1 | 12
Decreased fertility in females 1 | 20
Decreased male fertility 1 | 7
Diffusely thickened skin 1 | 20
Erectile dysfunction 1 | 32
Follicular adenoma 1 | 7
Galactorrhea 1 | 5
Growth hormone excess 1 | 14
Hyperinsulinaemic hypoglycaemia 1 | 16
Hyperinsulinemic hypoglycemia 1 | 17
Hyperphagia 1 | 23
Hyperphosphaturia 1 | 21
Hyperprolactinemia 1 | 27
Increased appetite (finding) 1 | 23
Increased serum parathyroid hormone 1 | 14
Insulinoma 1 | 24
Invasive Ductal Breast Carcinoma 1 | 9
Lipidoses 1 | 19
Lipoidosis 1 | 19
Multiple Endocrine Neoplasia Type 1 1 | 29
Multiple endocrine neoplasia type 2A 1 | 20
Multiple endocrine neoplasia type 2B 1 | 17
Pachyderma 1 | 20
Parathyroid Adenoma 1 | 19
Parathyroid carcinoma 1 | 7
Peptic Ulcer 1 | 27
Platyspondyly 1 | 56
Prolactinoma 1 | 11
Secondary hypothyroidism 1 | 15
Short tubular bones 1 | 22
Simple syndactyly of toes, first web space 1 | 23
Testicular hypogonadism 1 | 21
Thyroid Diseases 1 | 24
Thyroid Gland Follicular Adenoma 1 | 9
Tuberous sclerosis 1 | 19
Urine phosphorous concentration above normal 1 | 21
Zollinger-Ellison syndrome 1 | 18
menstrual periods stopped for over 6 months 1 | 13

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 5 | 12,091
Transcription Factor 3 | 1,400

GO Process

response to transforming growt... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Menin MEN1 Tchem Non-IDG -3.23460 1803.0 382
Matrix-remodeling-associated protein 5 MXRA5 Tdark Non-IDG -0.68586 5.20 48
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
Cbp/p300-interacting transactivator 1 CITED1 Tbio Non-IDG -1.74130 57.5 210
Runt-related transcription factor 3 RUNX3 Tbio Transcription Factor -2.71721 536.2 438
Fibronectin type III domain-containing protein 4 FNDC4 Tbio Non-IDG -0.20969 1.66 191
Zinc finger homeobox protein 3 ZFHX3 Tbio Transcription Factor -1.87242 83.8 71