Development Level

Tbio 42 | 11,445
Tchem 27 | 1,598
Tclin 19 | 613
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal seminal vesicle morph... 3 | 114
abnormal embryo size 2 | 220
abnormal epididymis morphology 2 | 42
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating insulin ... 2 | 76
decreased hemoglobin content 2 | 68
enlarged epididymis 2 | 31
enlarged heart 2 | 210
hyperactivity 2 | 148
increased circulating HDL chol... 2 | 80
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent testes 1 | 6
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating triglyce... 1 | 79
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
increased IgA level 1 | 1
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased grip strength 1 | 41
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 64 | 11,493
ovarian cancer 48 | 8,520
lung cancer 46 | 4,740
psoriasis 42 | 6,694
osteosarcoma 41 | 7,950
medulloblastoma, large-cell 40 | 6,241
Cancer 37 | 2,499
malignant mesothelioma 36 | 3,232
glioblastoma 35 | 5,792
atypical teratoid / rhabdoid tumor 30 | 5,112
Breast cancer 29 | 3,578
group 3 medulloblastoma 28 | 4,104
lung carcinoma 27 | 2,843
non-small cell lung cancer 27 | 2,890
ependymoma 24 | 4,679
lung adenocarcinoma 24 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
invasive ductal carcinoma 22 | 2,951
Schizophrenia 21 | 1,160
adult high grade glioma 21 | 3,801
pancreatic cancer 21 | 2,398
primitive neuroectodermal tumor 21 | 3,035
colon cancer 20 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
Astrocytoma, Pilocytic 18 | 3,081
diabetes mellitus 18 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
interstitial cystitis 17 | 2,312
pituitary cancer 17 | 1,972
Obesity 16 | 678
Prostatic Neoplasms 16 | 495
cystic fibrosis 16 | 1,696
tuberculosis 16 | 2,010
Depressive disorder 15 | 409
Autosomal recessive predisposition 14 | 1,442
Breast Neoplasms 14 | 445
Mammary Neoplasms 14 | 425
adrenocortical carcinoma 14 | 1,428
breast carcinoma 14 | 1,638
Kidney cancer 13 | 2,613
Liver Cirrhosis, Experimental 13 | 769
Lung Neoplasms 13 | 232
Pick disease 13 | 1,894
ductal carcinoma in situ 13 | 1,745
oligodendroglioma 13 | 2,850
ulcerative colitis 13 | 1,819
Atherosclerosis 12 | 291
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
subependymal giant cell astrocytoma 12 | 2,287
Bipolar Disorder 11 | 666
Epilepsy 11 | 792
Intellectual disability 11 | 1,016
astrocytoma 11 | 1,146
cutaneous lupus erythematosus 11 | 1,057
nasopharyngeal carcinoma 11 | 1,058
Alcoholic Intoxication, Chronic 10 | 289
Endometriosis 10 | 540
Seizures 10 | 596
Alzheimer's disease 9 | 658
Hypertension 9 | 396
Kidney disease 9 | 430
Mental Depression 9 | 333
Multiple Sclerosis 9 | 540
Multiple myeloma 9 | 1,332
Nerve Degeneration 9 | 121
active Crohn's disease 9 | 922
active ulcerative colitis 9 | 764
juvenile dermatomyositis 9 | 1,187
Amyotrophic lateral sclerosis 8 | 451
Arthritis 8 | 290
Diarrhea 8 | 253
Dull intelligence 8 | 645
Low intelligence 8 | 645
Melanoma 8 | 711
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Parkinson's disease 8 | 392
Poor school performance 8 | 645
Rheumatoid arthritis 8 | 1,191
Stomach Neoplasms 8 | 300
Vascular disease 8 | 319
esophageal adenocarcinoma 8 | 737
progressive supranuclear palsy 8 | 676
Asthma 7 | 385
Cerebrovascular disease 7 | 238
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Hepatomegaly 7 | 285
Hypersensitivity reaction type II disease 7 | 253
Major Depressive Disorder 7 | 301
Mental and motor retardation 7 | 608
Short stature 7 | 531
Small head 7 | 374
Waldenstrons macroglobulinemia 7 | 765
acute quadriplegic myopathy 7 | 1,158
astrocytic glioma 7 | 2,597
gastric cancer 7 | 459
gastric carcinoma 7 | 807
primary Sjogren syndrome 7 | 735
primary pancreatic ductal adenocarcinoma 7 | 1,109

Tissue

Digestive Tract 88 | 17,369
Endocrine System 88 | 18,159
Female tissues 86 | 17,400
Liver and Pancreas 86 | 16,750
Male tissues 85 | 17,142
Nervous System 85 | 16,725
Respiratory system 85 | 16,393
Skin and soft tissues 85 | 17,230
Urinary Tract 85 | 16,678
Blood and immune system 83 | 16,909
Cardiovascular System 77 | 15,192

Target Family

Non-IDG 32 | 12,091
Enzyme 23 | 4,145
Kinase 12 | 634
Transporter 9 | 473
oGPCR 5 | 421
Epigenetic 3 | 242
Ion Channel 3 | 344
Transcription Factor 3 | 1,400
GPCR 2 | 408
TF/Epigenetic 1 | 38

GO Process

response to toxic substance 93 | 93
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cystatin-C CST3 Tbio Non-IDG -3.52815 3278.8 866
Aquaporin-10 AQP10 Tbio Non-IDG -1.23305 16.1 85
Methylated-DNA--protein-cysteine methyltransferase MGMT Tchem Enzyme -3.13356 1426.9 560
Lysine-specific demethylase 5C KDM5C Tchem TF/Epigenetic -1.94004 86.4 135
Solute carrier family 23 member 1 SLC23A1 Tchem Transporter -1.82531 64.0 71
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 DHX15 Tbio Enzyme -1.74929 55.5 106
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.50460 33.8 170
Na(+)/H(+) exchange regulatory cofactor NHE-RF4 PDZD3 Tbio Non-IDG -0.76581 6.17 121
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.40865 2530.3 252
Heat-stable enterotoxin receptor GUCY2C Tclin Kinase -2.33494 214.5 228