Development Level

Tbio 18 | 10,625
Tchem 8 | 1,890
Tclin 5 | 602

IMPC Phenotype

abnormal embryo size 3 | 112
abnormal eye morphology 2 | 38
decreased fasted circulating g... 2 | 49
hydrops fetalis 2 | 22
immune system phenotype 2 | 17
microphthalmia 2 | 15
preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
abnormal eye size 1 | 11
abnormal heart morphology 1 | 51
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal retinal pigmentation 1 | 61
abnormal skin appearance 1 | 8
abnormal sleep behavior 1 | 63
anophthalmia 1 | 20
craniofacial phenotype 1 | 9
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating insulin ... 1 | 75
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
female infertility 1 | 34
herniated abdominal wall 1 | 4
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased bone mineral content 1 | 92
increased circulating bilirubi... 1 | 16
increased circulating triglyce... 1 | 24
increased heart rate variabili... 1 | 4
increased rib number 1 | 41
male infertility 1 | 62
pale yolk sac 1 | 12
prenatal lethality prior to he... 1 | 64
small adrenal glands 1 | 15
thrombocytopenia 1 | 46

Disease

Cancer 18 | 2,346
psoriasis 18 | 6,685
ovarian cancer 15 | 8,491
glioblastoma 12 | 5,572
diabetes mellitus 11 | 1,663
medulloblastoma, large-cell 11 | 6,234
osteosarcoma 11 | 7,933
Breast cancer 10 | 3,098
atypical teratoid / rhabdoid tumor 10 | 4,369
malignant mesothelioma 10 | 3,163
lung cancer 9 | 4,473
Prostatic Neoplasms 8 | 471
non-small cell lung cancer 8 | 2,798
astrocytoma 7 | 1,493
pancreatic cancer 7 | 2,300
Hypertensive disease 6 | 193
Kidney disease 6 | 397
colon cancer 6 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
lung adenocarcinoma 6 | 2,714
pediatric high grade glioma 6 | 2,712
Cerebrovascular disease 5 | 231
Obesity 5 | 616
adrenocortical carcinoma 5 | 1,427
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
lung carcinoma 5 | 2,844
oligodendroglioma 5 | 2,849
pilocytic astrocytoma 5 | 3,086
primitive neuroectodermal tumor 5 | 3,031
Asthma 4 | 349
Hypertension 4 | 293
Neoplasm Invasiveness 4 | 127
Vascular disease 4 | 281
Waldenstrons macroglobulinemia 4 | 764
adult high grade glioma 4 | 2,148
breast carcinoma 4 | 1,614
chronic rhinosinusitis 4 | 512
group 3 medulloblastoma 4 | 2,254
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
nasopharyngeal carcinoma 4 | 1,056
pituitary cancer 4 | 1,972
Acute kidney injury 3 | 65
Anemia 3 | 252
Atherosclerosis 3 | 275
Atopic dermatitis 3 | 944
Bradycardia 3 | 24
Carcinoma 3 | 2,147
Cardiomyopathies 3 | 90
Congestive heart failure 3 | 36
Coronary artery disease 3 | 240
Cushing's syndrome 3 | 47
Diabetic Retinopathy 3 | 53
Endometriosis 3 | 535
Heart failure 3 | 80
Hyperinsulinism 3 | 63
Hypoglycemia 3 | 81
Hypothyroidism 3 | 89
Liver Cirrhosis 3 | 101
Mammary Neoplasms 3 | 410
Melanoma 3 | 261
Multiple Sclerosis 3 | 498
Myocardial Ischemia 3 | 169
Peripheral Neuropathy 3 | 303
Pick disease 3 | 1,893
Portal hypertension 3 | 21
Pulmonary hypertension 3 | 52
Schizophrenia 3 | 503
active Crohn's disease 3 | 918
acute quadriplegic myopathy 3 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
cystic fibrosis 3 | 1,670
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 2,514
group 4 medulloblastoma 3 | 1,875
hepatocellular carcinoma 3 | 550
invasive ductal carcinoma 3 | 2,950
pancreatic carcinoma 3 | 567
posterior fossa group A ependymoma 3 | 1,511
posterior fossa group B ependymoma 3 | 1,530
sonic hedgehog group medulloblastoma 3 | 1,482
tuberculosis 3 | 1,563
ulcerative colitis 3 | 2,087
urothelial carcinoma 3 | 318
Alzheimer's disease 2 | 644
Arthritis 2 | 248
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
Heart disease 2 | 279
Lung disease 2 | 136
Metabolic syndrome X 2 | 155
Pituitary adenoma 2 | 35
Polycystic Ovary Syndrome 2 | 334
Prostate cancer 2 | 172
Reperfusion Injury 2 | 84
Type 2 diabetes mellitus 2 | 192
adrenocortical adenoma 2 | 134
fibroadenoma 2 | 557
inflammatory breast cancer 2 | 404
medulloblastoma 2 | 1,524
progressive supranuclear palsy 2 | 674

Tissue

Liver and Pancreas 31 | 18,135
Blood and immune system 30 | 17,994
Cardiovascular System 30 | 17,957
Digestive Tract 30 | 18,472
Endocrine System 30 | 18,511
Female tissues 30 | 18,646
Male tissues 30 | 17,968
Nervous System 30 | 18,560
Urinary Tract 30 | 18,443
Respiratory system 29 | 17,483
Skin and soft tissues 29 | 18,114

Target Family

Non-IDG 16 | 11,969
Enzyme 7 | 4,146
Kinase 3 | 634
Transcription Factor 3 | 1,400
GPCR 1 | 408
Ion Channel 1 | 341

GO Process

response to testosterone 31 | 31
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.86495 767.9 361
Progonadoliberin-1 GNRH1 Tbio Non-IDG -3.57398 3724.8 253
Calreticulin CALR Tbio Non-IDG -3.16449 1423.9 650
Vasopressin-neurophysin 2-copeptin AVP Tbio Non-IDG -3.91847 8071.2 168
CAD protein CAD Tchem Non-IDG -2.23424 164.6 201
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.97569 843.2 611
Heat shock factor protein 1 HSF1 Tbio Transcription Factor -2.26734 207.5 1100
Urotensin-2 UTS2 Tbio Non-IDG -2.53120 395.9 163
Endothelin-1 EDN1 Tbio Non-IDG -4.06586 12467.9 527
Thrombospondin-1 THBS1 Tbio Non-IDG -3.04674 1192.7 409