Development Level

Tbio 25 | 11,651
Tchem 6 | 1,388
Tclin 5 | 612

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
preweaning lethality, complete... 3 | 979
abnormal heart morphology 2 | 162
decreased fasted circulating g... 2 | 65
edema 2 | 59
microphthalmia 2 | 26
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
anophthalmia 1 | 33
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating insulin ... 1 | 76
decreased large unstained cell... 1 | 11
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased caudal vertebrae num... 1 | 7
increased circulating bilirubi... 1 | 16
increased circulating total pr... 1 | 28
increased heart left ventricle... 1 | 4
increased lymphocyte cell numb... 1 | 32
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small adrenal glands 1 | 16
thrombocytopenia 1 | 56

Disease

Cancer 21 | 2,499
psoriasis 18 | 6,694
ovarian cancer 17 | 8,520
osteosarcoma 16 | 7,950
Carcinoma 15 | 11,493
glioblastoma 14 | 5,792
Breast cancer 13 | 3,578
medulloblastoma, large-cell 13 | 6,241
atypical teratoid / rhabdoid tumor 11 | 5,112
diabetes mellitus 11 | 1,728
lung cancer 11 | 4,740
adult high grade glioma 9 | 3,801
ependymoma 9 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
malignant mesothelioma 9 | 3,232
non-small cell lung cancer 9 | 2,890
Autosomal recessive predisposition 8 | 1,442
Hypertensive disease 8 | 292
Prostatic Neoplasms 7 | 495
astrocytoma 7 | 1,146
colon cancer 7 | 1,478
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung adenocarcinoma 7 | 2,716
pancreatic cancer 7 | 2,398
Astrocytoma, Pilocytic 6 | 3,081
Bipolar Disorder 6 | 666
Hypertension 6 | 396
Kidney disease 6 | 430
group 4 medulloblastoma 6 | 1,855
interstitial cystitis 6 | 2,312
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
Anemia 5 | 365
Cerebrovascular disease 5 | 238
Obesity 5 | 678
Pick disease 5 | 1,894
Weight decreased 5 | 103
acute quadriplegic myopathy 5 | 1,158
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
chronic rhinosinusitis 5 | 512
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pituitary cancer 5 | 1,972
spina bifida 5 | 1,074
ulcerative colitis 5 | 1,819
Asthma 4 | 385
Brain disease 4 | 96
Cardiomyopathies 4 | 110
Cognitive delay 4 | 608
Depressive disorder 4 | 409
Failure to gain weight 4 | 365
Fetal Growth Retardation 4 | 189
Global developmental delay 4 | 608
Infant, Small for Gestational Age 4 | 176
Intellectual disability 4 | 1,016
Intrauterine retardation 4 | 176
Melanoma 4 | 711
Mental and motor retardation 4 | 608
Neoplasm Invasiveness 4 | 161
Pediatric failure to thrive 4 | 365
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
Vascular disease 4 | 319
Waldenstrons macroglobulinemia 4 | 765
ductal carcinoma in situ 4 | 1,745
invasive ductal carcinoma 4 | 2,951
nasopharyngeal carcinoma 4 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
urothelial carcinoma 4 | 318
Atherosclerosis 3 | 291
Atopic dermatitis 3 | 952
Coronary artery disease 3 | 268
Cushing's syndrome 3 | 48
Diarrhea 3 | 253
Endometriosis 3 | 540
Epilepsy 3 | 792
Heart disease 3 | 306
Hypoglycemia 3 | 152
Hypothyroidism 3 | 122
Kidney cancer 3 | 2,613
Liver Cirrhosis 3 | 181
Long philtrum 3 | 137
Major Depressive Disorder 3 | 301
Multiple Sclerosis 3 | 540
Myocardial Ischemia 3 | 169
Seizures 3 | 596
Short nose 3 | 132
Small nose 3 | 132
Unipolar Depression 3 | 250
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cystic fibrosis 3 | 1,696
fibroadenoma 3 | 559
hepatocellular carcinoma 3 | 547
juvenile dermatomyositis 3 | 1,187
pancreatic carcinoma 3 | 562

Tissue

Endocrine System 35 | 18,159
Urinary Tract 35 | 16,678
Female tissues 34 | 17,400
Male tissues 34 | 17,142
Skin and soft tissues 34 | 17,230
Digestive Tract 33 | 17,369
Liver and Pancreas 33 | 16,750
Blood and immune system 32 | 16,909
Respiratory system 32 | 16,393
Nervous System 31 | 16,725
Cardiovascular System 26 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 8 | 4,145
Kinase 5 | 634
Transcription Factor 5 | 1,400
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

response to testosterone 36 | 36
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Calreticulin CALR Tbio Non-IDG -3.19563 1544.2 778
Vasopressin-neurophysin 2-copeptin AVP Tbio Non-IDG -3.92570 8381.2 203
Progonadoliberin-1 GNRH1 Tbio Non-IDG -3.58850 3826.5 295
Heat shock factor protein 1 HSF1 Tbio Transcription Factor -2.27852 217.0 1246
Erythropoietin EPO Tbio Non-IDG -3.92285 8985.5 837
Casein kinase II subunit beta CSNK2B Tbio Kinase -2.72925 527.4 422
CASP8 and FADD-like apoptosis regulator CFLAR Tbio Non-IDG -2.89793 871.7 683