Development Level

Tbio 50 | 11,445
Tclin 5 | 613
Tdark 4 | 6,588
Tchem 1 | 1,598

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal coat-hair pigmentatio... 2 | 64
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
convulsive seizures 2 | 13
decreased fasted circulating g... 2 | 65
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
shortened RR interval 2 | 17
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal iris transilluminatio... 1 | 2
abnormal pelvic girdle bone mo... 1 | 12
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
embryonic lethality prior to o... 1 | 239
enlarged thymus 1 | 5
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased urine magnesium leve... 1 | 2
short tibia 1 | 97
shortened PR interval 1 | 6
thrombocytopenia 1 | 56

Disease

Carcinoma 40 | 11,493
Retinitis Pigmentosa 22 | 226
Autosomal recessive predisposition 18 | 1,442
psoriasis 18 | 6,694
osteosarcoma 17 | 7,950
Blindness 16 | 88
Fundus dystrophy 16 | 83
ovarian cancer 16 | 8,520
medulloblastoma, large-cell 14 | 6,241
Cataract 13 | 297
Nystagmus 13 | 317
group 3 medulloblastoma 13 | 4,104
Intellectual disability 12 | 1,016
Low Vision 12 | 174
Retinal Degeneration 12 | 106
Visual Impairment 12 | 174
Cone dystrophy 11 | 71
Glaucoma 11 | 239
Night Blindness 11 | 101
Obesity 11 | 678
Photodysphoria 11 | 121
Photophobia 11 | 121
cone-rod dystrophy 11 | 59
ependymoma 11 | 4,679
Difficulties with night vision 10 | 87
Electroretinogram abnormal 10 | 95
Lens Opacities 10 | 231
Breast cancer 9 | 3,578
Dull intelligence 9 | 645
Keratoconus 9 | 113
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Myopia 9 | 176
Optic Atrophy 9 | 242
Poor school performance 9 | 645
glioblastoma 9 | 5,792
pituitary cancer 9 | 1,972
Abnormality of retinal pigmentation 8 | 111
Congenital hypoplasia of penis 8 | 176
Hypogonadism 8 | 173
Kidney cancer 8 | 2,613
Retinal pigment epithelial abnormality 8 | 111
adult high grade glioma 8 | 3,801
atypical teratoid / rhabdoid tumor 8 | 5,112
Anteverted nostril 7 | 191
Blind Vision 7 | 111
Blindness, Legal 7 | 110
Broad flat nasal bridge 7 | 236
Leber congenital amaurosis 7 | 69
Nasal bridge wide 7 | 236
Sensorineural Hearing Loss (disorder) 7 | 284
lung carcinoma 7 | 2,843
Abnormality of the retinal vasculature 6 | 59
Atypical scarring of skin 6 | 62
Ciliopathy 6 | 71
Color vision defect 6 | 33
Conductive hearing loss 6 | 123
Congenital anomaly of testis 6 | 52
Hyperinsulinism 6 | 133
Night blindness, progressive 6 | 51
Ophthalmoplegia 6 | 106
astrocytic glioma 6 | 2,597
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
lung adenocarcinoma 6 | 2,716
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
Abnormal color vision 5 | 31
Age related macular degeneration 5 | 72
Color vision defect, severe 5 | 31
Cone/cone-rod dystrophy 5 | 20
Hypertensive disease 5 | 292
Reduced visual acuity 5 | 63
Usher syndrome 5 | 32
invasive ductal carcinoma 5 | 2,951
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
tuberculosis 5 | 2,010
Achromatopsia 4 | 16
Bardet-Biedl syndrome 4 | 51
Bardet-Biedl syndrome 1 4 | 22
Extinguished electroretinogram 4 | 15
Hyperopia 4 | 70
Increase in blood pressure 4 | 119
Liddle syndrome 4 | 14
Polydactyly 4 | 107
Recurrent respiratory infections 4 | 141
Retinal Dystrophies 4 | 33
Scotoma 4 | 22
Strabismus 4 | 270
gastric carcinoma 4 | 807
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
Failure to gain weight 3 | 365
Hypertension 3 | 396
Kidney disease 3 | 430
Pediatric failure to thrive 3 | 365
chronic rhinosinusitis 3 | 512

Tissue

Endocrine System 58 | 18,159
Digestive Tract 53 | 17,369
Female tissues 51 | 17,400
Male tissues 49 | 17,142
Skin and soft tissues 49 | 17,230
Liver and Pancreas 48 | 16,750
Nervous System 48 | 16,725
Urinary Tract 48 | 16,678
Blood and immune system 46 | 16,909
Respiratory system 42 | 16,393
Cardiovascular System 33 | 15,192

Target Family

Non-IDG 32 | 12,091
Enzyme 8 | 4,145
Transcription Factor 7 | 1,400
Ion Channel 6 | 344
Transporter 5 | 473
Kinase 2 | 634

GO Process

response to stimulus 60 | 60
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neural retina-specific leucine zipper protein NRL Tbio Transcription Factor -2.46080 279.4 74
Cone-rod homeobox protein CRX Tbio Transcription Factor -2.44826 272.0 185
Myosin-IIIb MYO3B Tbio Kinase -0.73450 5.14 127
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.39605 25.7 32
Retinaldehyde-binding protein 1 RLBP1 Tbio Non-IDG -2.14964 143.4 108
Metal transporter CNNM4 CNNM4 Tbio Non-IDG -1.18531 16.5 123
Uncharacterized protein C2orf71 C2orf71 Tbio Non-IDG -0.91200 8.96 29
Retinol dehydrogenase 8 RDH8 Tbio Enzyme -1.04003 12.6 0
Hemicentin-1 HMCN1 Tbio Non-IDG -1.25421 18.0 12
Protein FAM161A FAM161A Tbio Non-IDG -1.10138 14.2 50