Development Level

Tbio 19 | 11,445
Tchem 12 | 1,598
Tclin 6 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal seminal vesicle morph... 2 | 114
decreased circulating glucose ... 2 | 126
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
enlarged heart 2 | 210
abnormal adrenal gland morphol... 1 | 1
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal skin morphology 1 | 50
abnormal thymus morphology 1 | 7
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small thymus 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 26 | 11,493
Cancer 24 | 2,499
psoriasis 23 | 6,694
ovarian cancer 21 | 8,520
osteosarcoma 16 | 7,950
glioblastoma 15 | 5,792
lung cancer 15 | 4,740
malignant mesothelioma 15 | 3,232
medulloblastoma, large-cell 15 | 6,241
invasive ductal carcinoma 14 | 2,951
Breast cancer 13 | 3,578
lung carcinoma 13 | 2,843
pancreatic cancer 12 | 2,398
adult high grade glioma 11 | 3,801
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
interstitial cystitis 11 | 2,312
non-small cell lung cancer 11 | 2,890
pituitary cancer 11 | 1,972
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
ulcerative colitis 10 | 1,819
cystic fibrosis 9 | 1,696
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
lung adenocarcinoma 9 | 2,716
tuberculosis 9 | 2,010
Astrocytoma, Pilocytic 8 | 3,081
Liver Cirrhosis, Experimental 8 | 769
astrocytic glioma 8 | 2,597
breast carcinoma 8 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
primitive neuroectodermal tumor 8 | 3,035
acute quadriplegic myopathy 7 | 1,158
diabetes mellitus 7 | 1,728
esophageal adenocarcinoma 7 | 737
Autosomal recessive predisposition 6 | 1,442
Multiple myeloma 6 | 1,332
Obesity 6 | 678
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
astrocytoma 6 | 1,146
juvenile dermatomyositis 6 | 1,187
oligodendroglioma 6 | 2,850
primary pancreatic ductal adenocarcinoma 6 | 1,109
subependymal giant cell astrocytoma 6 | 2,287
Cleft Palate 5 | 271
Endometriosis 5 | 540
Hypertension 5 | 396
Kidney cancer 5 | 2,613
Pick disease 5 | 1,894
Seizures 5 | 596
Skin Neoplasms 5 | 69
cutaneous lupus erythematosus 5 | 1,057
ductal carcinoma in situ 5 | 1,745
fibroadenoma 5 | 559
gastric carcinoma 5 | 807
Arthritis 4 | 290
Breast Neoplasms 4 | 445
Carcinoma, Hepatocellular 4 | 228
Cleft Lip 4 | 141
Downward slant of palpebral fissure 4 | 158
Dull intelligence 4 | 645
Epilepsy 4 | 792
Hyperkeratosis 4 | 50
Intellectual disability 4 | 1,016
Liver carcinoma 4 | 240
Low intelligence 4 | 645
Mammary Neoplasms 4 | 425
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Prostatic Neoplasms 4 | 495
Stomach Neoplasms 4 | 300
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
group 4 medulloblastoma 4 | 1,855
mucosa-associated lymphoid tissue lymphoma 4 | 484
urothelial carcinoma 4 | 318
Adenoma 3 | 167
Alzheimer's disease 3 | 658
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Broad flat nasal bridge 3 | 236
Cerebrovascular disease 3 | 238
Depressive disorder 3 | 409
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Kidney disease 3 | 430
Lipid metabolism disorder 3 | 114
Nasal bridge wide 3 | 236
Vascular disease 3 | 319
chronic rhinosinusitis 3 | 512
dermatomyositis 3 | 966
medulloblastoma 3 | 720
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary Sjogren syndrome 3 | 735
spina bifida 3 | 1,074

Tissue

Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Nervous System 40 | 16,725
Blood and immune system 39 | 16,909
Digestive Tract 39 | 17,369
Male tissues 39 | 17,142
Skin and soft tissues 39 | 17,230
Urinary Tract 39 | 16,678
Respiratory system 38 | 16,393
Liver and Pancreas 37 | 16,750
Cardiovascular System 36 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 8 | 4,145
Nuclear Receptor 4 | 48
Kinase 3 | 634
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
TF/Epigenetic 1 | 38
Transporter 1 | 473

GO Process

response to retinoic acid 41 | 41
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ganglioside-induced differentiation-associated protein 2 GDAP2 Tbio Non-IDG -1.68199 45.5 78
Transmembrane protein 161A TMEM161A Tdark Non-IDG 0.22 0.80 102
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Pro-cathepsin H CTSH Tchem Enzyme -2.36930 222.0 253
Insulin-like growth factor-binding protein 2 IGFBP2 Tchem Non-IDG -2.93237 835.0 335
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Prostaglandin E synthase PTGES Tchem Enzyme -3.05403 1164.2 151