Development Level

Tbio 71 | 11,651
Tchem 16 | 1,388
Tclin 13 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to t... 4 | 278
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
decreased circulating bilirubi... 2 | 19
decreased circulating choleste... 2 | 93
decreased mean platelet volume 2 | 25
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
hemorrhage 2 | 23
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal locomotor activation 1 | 16
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal spine curvature 1 | 9
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal vitreous body morphol... 1 | 10
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent testes 1 | 6
anophthalmia 1 | 33
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
edema 1 | 59
embryonic growth retardation 1 | 106
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
respiratory system phenotype 1 | 2
small testis 1 | 58

Disease

Carcinoma 62 | 11,493
ovarian cancer 59 | 8,520
osteosarcoma 54 | 7,950
psoriasis 41 | 6,694
lung cancer 39 | 4,740
Cancer 35 | 2,499
medulloblastoma, large-cell 35 | 6,241
glioblastoma 29 | 5,792
Autosomal recessive predisposition 26 | 1,442
atypical teratoid / rhabdoid tumor 25 | 5,112
ependymoma 25 | 4,679
group 3 medulloblastoma 25 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
tuberculosis 24 | 2,010
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
Breast cancer 22 | 3,578
adult high grade glioma 19 | 3,801
lung adenocarcinoma 19 | 2,716
malignant mesothelioma 19 | 3,232
pancreatic cancer 19 | 2,398
Schizophrenia 18 | 1,160
Seizures 18 | 596
Epilepsy 17 | 792
astrocytic glioma 17 | 2,597
non-small cell lung cancer 17 | 2,890
Kidney cancer 16 | 2,613
interstitial cystitis 16 | 2,312
lung carcinoma 16 | 2,843
oligodendroglioma 16 | 2,850
Intellectual disability 15 | 1,016
diabetes mellitus 15 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
invasive ductal carcinoma 15 | 2,951
Muscle hypotonia 14 | 571
Toxic encephalopathy 14 | 141
Alzheimer's disease 13 | 658
Dull intelligence 13 | 645
Liver Cirrhosis, Experimental 13 | 769
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Poor school performance 13 | 645
Cerebellar Ataxia 12 | 304
Depressive disorder 12 | 409
Multiple myeloma 12 | 1,332
group 4 medulloblastoma 12 | 1,855
pituitary cancer 12 | 1,972
subependymal giant cell astrocytoma 12 | 2,287
Down syndrome 11 | 499
Hypertension 11 | 396
Parkinson's disease 11 | 392
Prostatic Neoplasms 11 | 495
cystic fibrosis 11 | 1,696
ductal carcinoma in situ 11 | 1,745
primitive neuroectodermal tumor 11 | 3,035
ulcerative colitis 11 | 1,819
Astrocytoma, Pilocytic 10 | 3,081
Hypertensive disease 10 | 292
Kidney disease 10 | 430
Lung Neoplasms 10 | 232
Melanoma 10 | 711
Nerve Degeneration 10 | 121
Pick disease 10 | 1,894
adrenocortical carcinoma 10 | 1,428
breast carcinoma 10 | 1,638
nasopharyngeal carcinoma 10 | 1,058
Breast Neoplasms 9 | 445
Failure to gain weight 9 | 365
Mammary Neoplasms 9 | 425
Pediatric failure to thrive 9 | 365
Sensorineural Hearing Loss (disorder) 9 | 284
Short stature 9 | 531
active ulcerative colitis 9 | 764
colon cancer 9 | 1,478
primary pancreatic ductal adenocarcinoma 9 | 1,109
Arthritis 8 | 290
Asthma 8 | 385
Cataract 8 | 297
Cockayne syndrome 8 | 60
Cognitive delay 8 | 608
Dementia 8 | 175
Dystonia 8 | 164
Fatigue 8 | 182
Global developmental delay 8 | 608
Heart failure 8 | 162
Hypogonadism 8 | 173
Lens Opacities 8 | 231
Mental and motor retardation 8 | 608
Muscle Spasticity 8 | 195
Neurodegenerative disease 8 | 414
Obesity 8 | 678
Optic Atrophy 8 | 242
Peripheral Neuropathy 8 | 134
Rheumatoid arthritis 8 | 1,191
Strabismus 8 | 270
Vascular disease 8 | 319
esophageal adenocarcinoma 8 | 737
gastric carcinoma 8 | 807
non primary Sjogren syndrome sicca 8 | 891

Tissue

Endocrine System 100 | 18,159
Liver and Pancreas 99 | 16,750
Male tissues 98 | 17,142
Blood and immune system 97 | 16,909
Female tissues 97 | 17,400
Urinary Tract 97 | 16,678
Digestive Tract 96 | 17,369
Nervous System 96 | 16,725
Respiratory system 96 | 16,393
Skin and soft tissues 96 | 17,230
Cardiovascular System 91 | 15,192

Target Family

Enzyme 53 | 4,145
Non-IDG 34 | 12,091
Kinase 7 | 634
Transporter 3 | 473
Epigenetic 2 | 242
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

GO Process

response to oxidative stress 101 | 101
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Oxidation resistance protein 1 OXR1 Tbio Non-IDG -1.67505 49.4 144
Dual oxidase 2 DUOX2 Tbio Enzyme -2.45061 251.8 126
Dual oxidase 1 DUOX1 Tbio Enzyme -2.50131 279.5 85
Alsin ALS2 Tbio Non-IDG -2.20492 161.9 180
Interactor protein for cytohesin exchange factors 1 IPCEF1 Tbio Non-IDG -0.36270 2.87 93
Bifunctional polynucleotide phosphatase/kinase PNKP Tbio Enzyme -1.79273 59.8 231
RNA-binding protein with multiple splicing RBPMS Tbio Non-IDG -2.12771 131.9 266
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546