Development Level

Tbio 62 | 10,625
Tchem 24 | 1,890
Tclin 14 | 602
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal coping response 2 | 12
abnormal retina morphology 2 | 100
decreased rib number 2 | 59
embryonic lethality prior to t... 2 | 187
hemorrhage 2 | 12
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal craniofacial morpholo... 1 | 12
abnormal embryo size 1 | 112
abnormal forebrain morphology 1 | 4
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal locomotor activation 1 | 26
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal snout morphology 1 | 18
abnormal tail morphology 1 | 17
abnormal tooth morphology 1 | 24
abnormal vitreous body morphol... 1 | 7
anophthalmia 1 | 20
cyanosis 1 | 6
decreased basophil cell number 1 | 11
decreased body weight 1 | 174
decreased circulating alanine ... 1 | 53
decreased circulating bilirubi... 1 | 14
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased total body fat amoun... 1 | 186
edema 1 | 11
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
hydrops fetalis 1 | 22
increased blood urea nitrogen ... 1 | 44
increased circulating bilirubi... 1 | 16
increased circulating potassiu... 1 | 31
increased heart weight 1 | 37
increased kidney weight 1 | 4
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
irregularly shaped pupil 1 | 7
microphthalmia 1 | 15
narrow eye opening 1 | 15
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
respiratory system phenotype 1 | 2

Disease

ovarian cancer 59 | 8,484
osteosarcoma 55 | 7,933
psoriasis 40 | 6,685
Cancer 38 | 2,346
lung cancer 35 | 4,466
medulloblastoma, large-cell 35 | 6,234
glioblastoma 31 | 5,572
atypical teratoid / rhabdoid tumor 23 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,289
lung adenocarcinoma 22 | 2,713
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
tuberculosis 21 | 1,557
Breast cancer 19 | 3,094
malignant mesothelioma 19 | 3,162
non-small cell lung cancer 19 | 2,798
pancreatic cancer 19 | 2,300
oligodendroglioma 18 | 2,849
Carcinoma 17 | 2,147
lung carcinoma 17 | 2,844
interstitial cystitis 16 | 2,299
invasive ductal carcinoma 16 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
ulcerative colitis 15 | 2,087
diabetes mellitus 14 | 1,663
ependymoma 14 | 2,514
Alzheimer's disease 13 | 644
astrocytic glioma 13 | 2,241
pediatric high grade glioma 13 | 2,712
pilocytic astrocytoma 13 | 3,086
pituitary cancer 13 | 1,972
primitive neuroectodermal tumor 13 | 3,031
Multiple myeloma 12 | 1,327
Pick disease 12 | 1,893
adult high grade glioma 12 | 2,148
ductal carcinoma in situ 12 | 1,745
group 3 medulloblastoma 12 | 2,254
posterior fossa group A ependymoma 12 | 1,511
subependymal giant cell astrocytoma 12 | 2,287
Prostatic Neoplasms 11 | 471
Toxic encephalopathy 11 | 131
adrenocortical carcinoma 11 | 1,427
cystic fibrosis 11 | 1,665
group 4 medulloblastoma 11 | 1,875
primary pancreatic ductal adenocarcinoma 11 | 1,271
sonic hedgehog group medulloblastoma 11 | 1,482
Down syndrome 10 | 548
Lung Neoplasms 10 | 171
Mammary Neoplasms 10 | 410
Parkinson's disease 10 | 364
Peripheral Neuropathy 10 | 303
Rheumatoid Arthritis 10 | 1,160
astrocytoma 10 | 1,493
colon cancer 10 | 1,475
medulloblastoma 10 | 1,524
nasopharyngeal carcinoma 10 | 1,056
Kidney disease 9 | 396
breast carcinoma 9 | 1,614
Arthritis 8 | 248
Asthma 8 | 349
Cockayne syndrome 8 | 54
Neurodegenerative disease 8 | 383
Obesity 8 | 616
Vascular disease 8 | 281
esophageal adenocarcinoma 8 | 737
non primary Sjogren syndrome sicca 8 | 840
Colorectal Neoplasms 7 | 217
Endometriosis 7 | 535
Hypertensive disease 7 | 193
Waldenstrons macroglobulinemia 7 | 765
aldosterone-producing adenoma 7 | 664
atypical teratoid/rhabdoid tumor 7 | 1,095
cutaneous lupus erythematosus 7 | 1,056
gastric carcinoma 7 | 832
pancreatic carcinoma 7 | 567
progressive supranuclear palsy 7 | 674
Atherosclerosis 6 | 275
Atopic dermatitis 6 | 944
Dementia 6 | 129
Diabetes mellitus type 2 6 | 69
Esophageal Neoplasms 6 | 67
Mammary Neoplasms, Experimental 6 | 150
Nerve Degeneration 6 | 73
Photosensitive trichothiodystrophy 6 | 24
Stomach Neoplasms 6 | 282
Treatment Refractory Type 2 Diabetes Mellitus 6 | 53
Xeroderma pigmentosum 6 | 41
active Crohn's disease 6 | 918
acute myeloid leukemia 6 | 780
acute quadriplegic myopathy 6 | 1,157
chronic rhinosinusitis 6 | 512
dermatomyositis 6 | 933
hepatocellular carcinoma 6 | 532
inflammatory breast cancer 6 | 404
spina bifida 6 | 1,064
Contact Dermatitis 5 | 80
Coronary artery disease 5 | 240
IGA Glomerulonephritis 5 | 454
Schizophrenia 5 | 501
juvenile dermatomyositis 5 | 1,189

Tissue

Blood and immune system 102 | 17,995
Cardiovascular System 102 | 17,958
Liver and Pancreas 102 | 18,136
Endocrine System 101 | 18,512
Female tissues 101 | 18,647
Nervous System 101 | 18,561
Respiratory system 101 | 17,484
Digestive Tract 100 | 18,473
Male tissues 100 | 17,969
Skin and soft tissues 100 | 18,115
Urinary Tract 100 | 18,444

Target Family

Enzyme 51 | 4,146
Non-IDG 35 | 11,971
Kinase 8 | 634
Transporter 3 | 473
Epigenetic 2 | 242
Ion Channel 2 | 341
Transcription Factor 1 | 1,400

GO Process

response to oxidative stress 102 | 102
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Angiopoietin-related protein 7 ANGPTL7 Tbio Non-IDG -1.31141 23.5 273
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.20847 1594.9 391
N-glycosylase/DNA lyase OGG1 Tbio Enzyme -3.23405 1747.3 234
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.16121 152.6 207
Glutathione synthetase GSS Tbio Enzyme -2.75264 568.9 200
Nicotinate phosphoribosyltransferase NAPRT Tbio Enzyme -1.20896 15.7 91
Lactoperoxidase LPO Tbio Enzyme -2.69742 442.5 160
Selenoprotein P SELENOP Tbio Non-IDG -2.42408 315.2 94
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648
7,8-dihydro-8-oxoguanine triphosphatase NUDT1 Tchem Enzyme -2.22783 223.6 143