Development Level

Tclin 17 | 613
Tbio 11 | 11,445
Tchem 9 | 1,598

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
decreased vertical activity 2 | 208
abnormal epididymis morphology 1 | 42
abnormal joint morphology 1 | 23
abnormal optic disc morphology 1 | 10
abnormal vitreous body morphol... 1 | 10
absent testes 1 | 6
brachydactyly 1 | 19
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased fasted circulating g... 1 | 65
decreased large unstained cell... 1 | 11
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
syndactyly 1 | 23

Disease

Carcinoma 24 | 11,493
glioblastoma 17 | 5,792
psoriasis 16 | 6,694
Schizophrenia 15 | 1,160
osteosarcoma 15 | 7,950
Cancer 14 | 2,499
medulloblastoma, large-cell 14 | 6,241
ovarian cancer 14 | 8,520
Bipolar Disorder 13 | 666
Depressive disorder 13 | 409
Nicotine dependence 12 | 54
lung cancer 12 | 4,740
Mental Depression 11 | 333
adult high grade glioma 11 | 3,801
diabetes mellitus 11 | 1,728
Alcoholic Intoxication, Chronic 10 | 289
Autosomal recessive predisposition 10 | 1,442
Breast cancer 10 | 3,578
atypical teratoid / rhabdoid tumor 10 | 5,112
ependymoma 10 | 4,679
group 3 medulloblastoma 10 | 4,104
Attention deficit hyperactivity disorder 9 | 278
Epilepsy 9 | 792
Hypertension 9 | 396
Hypertensive disease 9 | 292
Parkinson's disease 9 | 392
Seizures 9 | 596
Substance Withdrawal Syndrome 9 | 55
malignant mesothelioma 9 | 3,232
Alcohol dependence 8 | 107
Cocaine Dependence 8 | 51
Diabetes Mellitus, Non-Insulin-Dependent 8 | 145
Neuropathy 8 | 261
Obesity 8 | 678
invasive ductal carcinoma 8 | 2,951
primitive neuroectodermal tumor 8 | 3,035
Alzheimer's disease 7 | 658
Asthma 7 | 385
Astrocytoma, Pilocytic 7 | 3,081
Autistic Disorder 7 | 364
Blepharoptosis 7 | 231
Hyperglycemia 7 | 137
Smoking cessation assistance 7 | 8
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung adenocarcinoma 7 | 2,716
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
pituitary cancer 7 | 1,972
ulcerative colitis 7 | 1,819
Attention Deficit Disorder with Hyperactivity 6 | 21
Cerebrovascular disease 6 | 238
Diabetes Mellitus, Experimental 6 | 108
Diabetes Mellitus, Type 2 6 | 142
Lung disease 6 | 142
Major Depressive Disorder 6 | 301
Mood Disorders 6 | 184
Nerve Degeneration 6 | 121
Toxic encephalopathy 6 | 141
colon cancer 6 | 1,478
cystic fibrosis 6 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
oligodendroglioma 6 | 2,850
Brain disease 5 | 96
Cocaine-Related Disorders 5 | 92
Dementia 5 | 175
Dystonia 5 | 164
Fetal Growth Retardation 5 | 189
General anesthesia 5 | 53
Heart disease 5 | 306
Huntington's disease 5 | 76
Hyperalgesia 5 | 83
Infant, Small for Gestational Age 5 | 176
Inflammation 5 | 120
Intrauterine retardation 5 | 176
Kidney disease 5 | 430
Muscle relaxation, function 5 | 8
Niacin deficiency 5 | 5
Nicotine Withdrawal Symptoms 5 | 5
Pain 5 | 103
Pancreatitis 5 | 123
Pellagra 5 | 26
Unipolar Depression 5 | 250
juvenile dermatomyositis 5 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
subependymal giant cell astrocytoma 5 | 2,287
Allergic rhinitis 4 | 94
Arthritis 4 | 290
Brain Ischemia 4 | 110
Byzanthine arch palate 4 | 194
Infantile onset 4 | 238
Inflammatory bowel disease 4 | 151
Liver Cirrhosis 4 | 181
Lung Neoplasms 4 | 232
Multiple Sclerosis 4 | 540
Pick disease 4 | 1,894
Reperfusion Injury 4 | 86
acute quadriplegic myopathy 4 | 1,158
breast carcinoma 4 | 1,638

Tissue

Endocrine System 36 | 18,159
Digestive Tract 32 | 17,369
Liver and Pancreas 31 | 16,750
Nervous System 31 | 16,725
Blood and immune system 30 | 16,909
Female tissues 30 | 17,400
Male tissues 30 | 17,142
Skin and soft tissues 30 | 17,230
Urinary Tract 28 | 16,678
Respiratory system 27 | 16,393
Cardiovascular System 21 | 15,192

Target Family

Ion Channel 12 | 344
Non-IDG 9 | 12,091
Enzyme 5 | 4,145
GPCR 3 | 408
Transcription Factor 3 | 1,400
Transporter 3 | 473
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

response to nicotine 37 | 37
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuronal acetylcholine receptor subunit beta-2 CHRNB2 Tclin Ion Channel -1.62448 37.6 174
Acetylcholine receptor subunit alpha CHRNA1 Tclin Ion Channel -1.66400 41.7 307
Guanine nucleotide-binding protein G(t) subunit alpha-3 GNAT3 Tbio Non-IDG -2.28370 189.3 111
Sodium-dependent dopamine transporter SLC6A3 Tclin Transporter -3.59848 3752.4 324
Neuronal acetylcholine receptor subunit alpha-7 CHRFAM7A Tchem Ion Channel -1.81173 87.7 226
NADH-ubiquinone oxidoreductase chain 4 MT-ND4 Tclin Enzyme -3.03991 1074.3 9
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.36445 252.7 605
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.84388 738.4 199
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.12480 136.2 116
Cannabinoid receptor 1 CNR1 Tclin GPCR -3.71368 5235.6 431