Development Level

Tbio 5 | 11,445

IMPC Phenotype

abnormal behavior 2 | 298
preweaning lethality, complete... 2 | 979
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased mean corpuscular hem... 1 | 50
decreased red blood cell distr... 1 | 41
increased body length 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112

Disease

osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Carcinoma 3 | 11,493
psoriasis 3 | 6,694
Cancer 2 | 2,499
Neurodegenerative disease 2 | 414
Schizophrenia 2 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
spina bifida 2 | 1,074
Abnormal lower motor neuron morphology 1 | 6
Age related macular degeneration 1 | 72
Alkaline phosphatase serum increased 1 | 29
Anxiety 1 | 136
Anxiety disease 1 | 113
Apathy 1 | 16
Behavioral variant of frontotemporal dementia 1 | 8
Bone pain 1 | 42
Bulbar palsy 1 | 19
Bulbar weakness 1 | 19
Collapse of vertebra 1 | 14
Compression fracture of vertebral column 1 | 14
Compulsive hoarding 1 | 7
Cortical white matter abnormalities seen on MRI 1 | 18
Cranial nerve palsies 1 | 11
Deglutition Disorders 1 | 132
Developmental arithmetic disorder 1 | 8
Dysgraphia 1 | 20
Dyslexia 1 | 43
Dysphasia 1 | 23
Dyspnea 1 | 76
EMG positive sharp waves 1 | 2
EMG: myopathic abnormalities 1 | 22
EMG: myotonic discharges 1 | 2
Early tooth exfoliation 1 | 17
Echolalia 1 | 12
Excess nuchal skin 1 | 30
Fatigue 1 | 182
Fatty replacement of skeletal muscle 1 | 3
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Forgetful 1 | 40
Frontotemporal cerebral atrophy 1 | 8
Frontotemporal dementia 1 | 51
Gait, Drop Foot 1 | 24
Hydroxyprolinuria 1 | 7
Hyperorality 1 | 7
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 1 | 13
Irritation - emotion 1 | 68
Language Disorders 1 | 13
Leri-Weill dyschondrosteosis 1 | 7
Leukoaraiosis 1 | 18
Lewy Body Disease 1 | 21
Limited shoulder movement 1 | 3
Limited wrist extension 1 | 2
Long bone fractures 1 | 2
Long tract signs 1 | 3
Loss of speech 1 | 16
Lytic lesion 1 | 32
Macular degeneration 1 | 65
Memory Loss 1 | 40
Memory impairment 1 | 40
Mildly increased creatine kinase 1 | 20
Mood swings 1 | 77
Muscle Cramp 1 | 55
Muscle fiber inclusion bodies 1 | 4
Muscular fasciculation 1 | 22
Mutism 1 | 17
Myocardial Infarction 1 | 151
NONAKA MYOPATHY 1 | 2
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Osteitis Deformans 1 | 11
Paget Disease of Bone 2, Early-Onset 1 | 2
Paget's disease of bone 1 | 36
Pain 1 | 103
Paralysed 1 | 42
Paraparesis 1 | 6
Poor speech 1 | 37
Posterior fossa compression syndrome 1 | 2
Premature tooth loss 1 | 17
Problems speaking 1 | 37
Quadriparesis 1 | 8
Reflex, Ankle, Absent 1 | 8
Respiratory Failure 1 | 104
Restlessness 1 | 14
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7
Rimmed vacuoles on biopsy 1 | 15
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Social disinhibition 1 | 14
Stereotyped Behavior 1 | 37
Stereotypic Movement Disorder 1 | 42
Variation in muscle fiber size 1 | 16
Vici syndrome 1 | 14
Weakness of hip flexors 1 | 2
Xerostomia 1 | 42

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 5 | 12,091

GO Process

response to mitochondrial depo... 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Activating molecule in BECN1-regulated autophagy protein 1 AMBRA1 Tbio Non-IDG -1.56899 41.8 254
Sequestosome-1 SQSTM1 Tbio Non-IDG -2.78728 635.1 766
Beclin 1-associated autophagy-related key regulator ATG14 Tbio Non-IDG -1.63390 38.6 127
Autophagy-related protein 13 ATG13 Tbio Non-IDG -1.54032 28.8 400
Beclin-1 BECN1 Tbio Non-IDG -3.24545 1556.0 1075