Development Level

Tbio 86 | 10,625
Tchem 50 | 1,890
Tclin 25 | 602

IMPC Phenotype

preweaning lethality, incomple... 6 | 260
abnormal bone structure 4 | 131
decreased bone mineral content 4 | 157
decreased heart weight 4 | 44
decreased lean body mass 4 | 195
preweaning lethality, complete... 4 | 633
abnormal behavior 3 | 226
decreased body weight 3 | 174
decreased bone mineral density 3 | 126
decreased monocyte cell number 3 | 28
increased circulating HDL chol... 3 | 63
increased circulating alkaline... 3 | 119
short tibia 3 | 82
abnormal bone mineralization 2 | 55
abnormal humerus morphology 2 | 11
abnormal joint morphology 2 | 14
abnormal seminal vesicle morph... 2 | 47
abnormal tibia morphology 2 | 14
decreased KLRG1+ CD8 alpha bet... 2 | 8
decreased body length 2 | 108
decreased circulating alkaline... 2 | 41
decreased circulating choleste... 2 | 85
decreased circulating free fat... 2 | 39
decreased circulating insulin ... 2 | 75
decreased circulating serum al... 2 | 79
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
decreased spleen weight 2 | 13
decreased total body fat amoun... 2 | 186
enlarged heart 2 | 111
increased NK cell number 2 | 19
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
abnormal QRS complex 1 | 25
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal optic disc morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 11
abnormal rib morphology 1 | 28
abnormal spleen morphology 1 | 36
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 14
abnormal vocalization 1 | 21
cataract 1 | 26
convulsive seizures 1 | 11
corneal opacity 1 | 25
decreased CD5-positive Ly6C-po... 1 | 4
decreased Ly6C low monocyte nu... 1 | 23
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating iron lev... 1 | 25
decreased hemoglobin content 1 | 53
decreased kidney weight 1 | 7
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased pulmonary respirator... 1 | 4
decreased threshold for audito... 1 | 32
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
hypoactivity 1 | 89
increased B cell number 1 | 23
increased T cell number 1 | 15
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating triglyce... 1 | 24
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mature B cell number 1 | 12
increased respiratory quotient 1 | 12
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
narrow eye opening 1 | 15
small heart 1 | 8
small kidney 1 | 10
small spleen 1 | 11
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34
vertebral fusion 1 | 23

Disease

psoriasis 94 | 6,685
Cancer 93 | 2,346
ovarian cancer 87 | 8,491
osteosarcoma 81 | 7,933
lung cancer 71 | 4,473
glioblastoma 65 | 5,572
medulloblastoma, large-cell 57 | 6,234
ulcerative colitis 56 | 2,087
interstitial cystitis 54 | 2,299
lung carcinoma 50 | 2,844
invasive ductal carcinoma 49 | 2,950
non-small cell lung cancer 45 | 2,798
malignant mesothelioma 44 | 3,163
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,956
pilocytic astrocytoma 39 | 3,086
diabetes mellitus 38 | 1,663
lung adenocarcinoma 38 | 2,714
Breast cancer 37 | 3,098
Rheumatoid Arthritis 37 | 1,170
intraductal papillary-mucinous neoplasm (IPMN) 36 | 3,289
pancreatic cancer 36 | 2,300
tuberculosis 36 | 1,563
cutaneous lupus erythematosus 35 | 1,056
atypical teratoid / rhabdoid tumor 33 | 4,369
cystic fibrosis 32 | 1,670
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,988
Hypersensitivity reaction type II disease 29 | 235
Multiple Sclerosis 29 | 498
pituitary cancer 29 | 1,972
posterior fossa group A ependymoma 29 | 1,511
Arthritis 28 | 248
subependymal giant cell astrocytoma 28 | 2,287
breast carcinoma 27 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,795
pediatric high grade glioma 27 | 2,712
Kidney disease 25 | 397
Atherosclerosis 23 | 275
Lung disease 23 | 136
adrenocortical carcinoma 23 | 1,427
colon cancer 23 | 1,475
group 4 medulloblastoma 23 | 1,875
Coronary artery disease 22 | 240
Obesity 22 | 616
adult high grade glioma 22 | 2,148
primary Sjogren syndrome 22 | 788
primitive neuroectodermal tumor 22 | 3,031
Cerebrovascular disease 21 | 231
Hypertension 21 | 293
Asthma 20 | 349
ductal carcinoma in situ 20 | 1,745
gastric carcinoma 20 | 832
juvenile dermatomyositis 20 | 1,189
oligodendroglioma 20 | 2,849
Liver disease 19 | 219
acute myeloid leukemia 19 | 785
astrocytoma 19 | 1,493
Atopic dermatitis 18 | 944
Inflammatory bowel disease 18 | 142
Heart disease 17 | 279
Inflammation 17 | 109
Prostatic Neoplasms 17 | 471
Vascular disease 17 | 281
active Crohn's disease 17 | 918
aldosterone-producing adenoma 17 | 664
ependymoma 17 | 2,514
Alzheimer's disease 16 | 644
Endometriosis 16 | 535
Carcinoma 15 | 2,147
pancreatic carcinoma 15 | 567
periodontitis 15 | 269
primary pancreatic ductal adenocarcinoma 15 | 1,271
sonic hedgehog group medulloblastoma 15 | 1,482
Hypertensive disease 14 | 193
Mammary Neoplasms 14 | 410
Reperfusion Injury 14 | 84
Waldenstrons macroglobulinemia 14 | 764
mucosa-associated lymphoid tissue lymphoma 14 | 480
nasopharyngeal carcinoma 14 | 1,056
sarcoidosis 14 | 368
Crohn's disease 13 | 304
Multiple myeloma 13 | 1,327
Parkinson's disease 13 | 364
atypical teratoid/rhabdoid tumor 13 | 1,095
chronic lymphocytic leukemia 13 | 244
group 3 medulloblastoma 13 | 2,254
hepatocellular carcinoma 13 | 550
posterior fossa group B ependymoma 13 | 1,530
Liver carcinoma 12 | 217
Peripheral Neuropathy 12 | 303
Pick disease 12 | 1,893
Status Epilepticus 12 | 85
Toxic encephalopathy 12 | 131
acute quadriplegic myopathy 12 | 1,157
chronic rhinosinusitis 12 | 512
dermatomyositis 12 | 966
nephrosclerosis 12 | 329
Myocardial Ischemia 11 | 169
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 499
esophageal adenocarcinoma 11 | 737
inflammatory breast cancer 11 | 404

Tissue

Digestive Tract 161 | 18,472
Female tissues 160 | 18,646
Liver and Pancreas 160 | 18,135
Male tissues 160 | 17,968
Skin and soft tissues 160 | 18,114
Urinary Tract 160 | 18,443
Endocrine System 159 | 18,511
Nervous System 159 | 18,560
Blood and immune system 158 | 17,994
Cardiovascular System 158 | 17,957
Respiratory system 158 | 17,483

Target Family

Non-IDG 85 | 11,969
Enzyme 37 | 4,146
GPCR 12 | 408
Kinase 12 | 634
Transcription Factor 8 | 1,400
Transporter 3 | 473
Epigenetic 2 | 242
Ion Channel 2 | 341

GO Process

response to lipopolysaccharide 161 | 161
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paralemmin-3 PALM3 Tbio Non-IDG -0.47712 3.44 66
T-cell surface protein tactile CD96 Tbio Non-IDG -2.03517 108.7 142
E-selectin SELE Tchem Non-IDG -3.43650 2598.8 820
Tyrosine-protein kinase Fer FER Tchem Kinase -1.84299 53.1 358
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.78255 613.4 202
Cytochrome P450 1A1 CYP1A1 Tchem Non-IDG -3.53853 3553.5 340
Lymphocyte antigen 96 LY96 Tbio Non-IDG -2.73333 490.7 314
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.39396 233.2 634
Erbin ERBIN Tbio Non-IDG -1.68182 53.5 111
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.12726 13094.7 961