Development Level

Tbio 92 | 11,445
Tchem 43 | 1,598
Tclin 25 | 613

IMPC Phenotype

decreased vertical activity 7 | 208
preweaning lethality, incomple... 7 | 499
abnormal bone structure 5 | 187
preweaning lethality, complete... 5 | 979
abnormal behavior 3 | 298
cataract 3 | 92
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
hyperactivity 3 | 148
increased lymphocyte cell numb... 3 | 32
increased neutrophil cell numb... 3 | 46
abnormal clavicle morphology 2 | 6
abnormal digit morphology 2 | 10
abnormal humerus morphology 2 | 11
abnormal joint morphology 2 | 23
abnormal lens morphology 2 | 81
abnormal optic disc morphology 2 | 10
abnormal seminal vesicle morph... 2 | 114
abnormal tibia morphology 2 | 14
abnormal vertebrae morphology 2 | 18
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased heart weight 2 | 27
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
enlarged heart 2 | 210
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased eosinophil cell numb... 2 | 11
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal facial morphology 1 | 17
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal pelvic girdle bone mo... 1 | 12
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased pulmonary respirator... 1 | 5
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged spleen 1 | 41
enlarged uterus 1 | 11
fused cornea and lens 1 | 5
impaired pupillary reflex 1 | 26
increased T cell number 1 | 6
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
iris synechia 1 | 3
limb grasping 1 | 41
microphthalmia 1 | 26
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
small heart 1 | 10
small kidney 1 | 16
small spleen 1 | 19
small superior vagus ganglion 1 | 74
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Cancer 94 | 2,499
psoriasis 92 | 6,694
ovarian cancer 88 | 8,520
Carcinoma 82 | 11,493
osteosarcoma 80 | 7,950
lung cancer 73 | 4,740
glioblastoma 67 | 5,792
medulloblastoma, large-cell 58 | 6,241
interstitial cystitis 55 | 2,312
lung carcinoma 54 | 2,843
invasive ductal carcinoma 49 | 2,951
Breast cancer 48 | 3,578
non-small cell lung cancer 48 | 2,890
ulcerative colitis 48 | 1,819
malignant mesothelioma 46 | 3,232
ependymoma 44 | 4,679
tuberculosis 42 | 2,010
pancreatic cancer 41 | 2,398
atypical teratoid / rhabdoid tumor 40 | 5,112
lung adenocarcinoma 40 | 2,716
Rheumatoid arthritis 39 | 1,191
diabetes mellitus 39 | 1,728
Astrocytoma, Pilocytic 37 | 3,081
Autosomal recessive predisposition 37 | 1,442
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,291
adult high grade glioma 34 | 3,801
cutaneous lupus erythematosus 34 | 1,057
cystic fibrosis 34 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
pituitary cancer 31 | 1,972
Arthritis 30 | 290
Hypertension 30 | 396
Liver Cirrhosis, Experimental 30 | 769
Multiple Sclerosis 30 | 540
breast carcinoma 30 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,962
Schizophrenia 29 | 1,160
Hypersensitivity reaction type II disease 28 | 253
group 3 medulloblastoma 28 | 4,104
colon cancer 25 | 1,478
subependymal giant cell astrocytoma 25 | 2,287
Cerebrovascular disease 24 | 238
Lung disease 24 | 142
adrenocortical carcinoma 24 | 1,428
primitive neuroectodermal tumor 24 | 3,035
Asthma 23 | 385
Kidney disease 23 | 430
Atherosclerosis 22 | 291
Coronary artery disease 22 | 268
Hypertensive disease 22 | 292
Obesity 22 | 678
ductal carcinoma in situ 22 | 1,745
Heart disease 21 | 306
aldosterone-producing adenoma 21 | 665
oligodendroglioma 21 | 2,850
Atopic dermatitis 20 | 952
Depressive disorder 20 | 409
group 4 medulloblastoma 20 | 1,855
Liver disease 19 | 237
Prostatic Neoplasms 19 | 495
acute myeloid leukemia 19 | 783
juvenile dermatomyositis 19 | 1,187
primary Sjogren syndrome 19 | 735
Inflammation 18 | 120
Inflammatory bowel disease 18 | 151
gastric carcinoma 18 | 807
Bipolar Disorder 17 | 666
Kidney cancer 17 | 2,613
Mental Depression 17 | 333
Vascular disease 17 | 319
active Crohn's disease 17 | 922
pediatric high grade glioma 17 | 1,064
Alzheimer's disease 16 | 658
Breast Neoplasms 16 | 445
Mammary Neoplasms 16 | 425
Seizures 16 | 596
periodontitis 16 | 293
Endometriosis 15 | 540
Fever 15 | 138
Liver Cirrhosis 15 | 181
Major Depressive Disorder 15 | 301
nasopharyngeal carcinoma 15 | 1,058
pancreatic carcinoma 15 | 562
primary pancreatic ductal adenocarcinoma 15 | 1,109
Epilepsy 14 | 792
Hyperalgesia 14 | 83
Liver carcinoma 14 | 240
Reperfusion Injury 14 | 86
active ulcerative colitis 14 | 764
astrocytoma 14 | 1,146
mucosa-associated lymphoid tissue lymphoma 14 | 484
Carcinoma, Hepatocellular 13 | 228
Lung Neoplasms 13 | 232
Parkinson's disease 13 | 392
Short stature 13 | 531
Unipolar Depression 13 | 250
chronic rhinosinusitis 13 | 512
hepatocellular carcinoma 13 | 547
nephrosclerosis 13 | 333

Tissue

Blood and immune system 160 | 16,909
Digestive Tract 160 | 17,369
Endocrine System 159 | 18,159
Male tissues 159 | 17,142
Urinary Tract 159 | 16,678
Female tissues 158 | 17,400
Liver and Pancreas 157 | 16,750
Skin and soft tissues 157 | 17,230
Respiratory system 155 | 16,393
Nervous System 152 | 16,725
Cardiovascular System 140 | 15,192

Target Family

Non-IDG 86 | 12,091
Enzyme 36 | 4,145
Kinase 13 | 634
GPCR 12 | 408
Transcription Factor 7 | 1,400
Transporter 3 | 473
Ion Channel 2 | 344
Epigenetic 1 | 242

GO Process

response to lipopolysaccharide 160 | 160
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-18-binding protein IL18BP Tbio Non-IDG -2.00596 101.6 307
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.40865 2530.3 252
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.80099 639.3 247
Protein S100-A14 S100A14 Tbio Non-IDG -1.26543 22.8 50
Paralemmin-3 PALM3 Tbio Non-IDG -0.66901 5.71 76
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
Proteinase-activated receptor 1 F2R Tclin GPCR -2.78393 551.0 453
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.41628 245.1 733