Development Level

Tbio 37 | 11,445
Tchem 8 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
abnormal bone mineralization 2 | 38
decreased bone mineral density 2 | 126
decreased lean body mass 2 | 135
increased bone mineral density 2 | 72
increased total body fat amoun... 2 | 134
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal limb morphology 1 | 13
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased eosinophil cell numb... 1 | 24
decreased lumbar vertebrae num... 1 | 2
decreased red blood cell distr... 1 | 41
decreased sacral vertebrae num... 1 | 1
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased lumbar vertebrae num... 1 | 1
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased sacral vertebrae num... 1 | 1
prenatal lethality prior to he... 1 | 87
thrombocytopenia 1 | 56
thrombocytosis 1 | 27

Disease

Carcinoma 36 | 11,493
ovarian cancer 29 | 8,520
osteosarcoma 24 | 7,950
Breast cancer 19 | 3,578
group 3 medulloblastoma 17 | 4,104
malignant mesothelioma 17 | 3,232
medulloblastoma, large-cell 17 | 6,241
Cancer 16 | 2,499
lung cancer 14 | 4,740
psoriasis 14 | 6,694
Breast Neoplasms 11 | 445
Mammary Neoplasms 11 | 425
ependymoma 11 | 4,679
non-small cell lung cancer 11 | 2,890
glioblastoma 10 | 5,792
atypical teratoid / rhabdoid tumor 9 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Fanconi anemia 8 | 56
diabetes mellitus 8 | 1,728
breast carcinoma 7 | 1,638
lung adenocarcinoma 7 | 2,716
primitive neuroectodermal tumor 7 | 3,035
Ataxia telangiectasia 6 | 34
Autosomal recessive predisposition 6 | 1,442
Chromosome Breakage 6 | 36
Kidney cancer 6 | 2,613
Prostatic Neoplasms 6 | 495
astrocytic glioma 6 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
oligodendroglioma 6 | 2,850
Intellectual disability 5 | 1,016
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
Short stature 5 | 531
adrenocortical carcinoma 5 | 1,428
cutaneous lupus erythematosus 5 | 1,057
gastric carcinoma 5 | 807
nasopharyngeal carcinoma 5 | 1,058
non primary Sjogren syndrome sicca 5 | 891
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Anemia 4 | 365
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 4 | 9
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Hypertension 4 | 396
Hypertensive disease 4 | 292
Increased chromosomal breakage 4 | 27
Liver cancer 4 | 604
Low intelligence 4 | 645
Malignant neoplasm of breast 4 | 15
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Nijmegen breakage syndrome 4 | 24
Ovarian Neoplasms 4 | 102
Poor school performance 4 | 645
Xeroderma pigmentosum 4 | 43
adult high grade glioma 4 | 3,801
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
ovarian neoplasm 4 | 99
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
Abdominal Pain 3 | 98
Alzheimer's disease 3 | 658
Atherosclerosis 3 | 291
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 3 | 13
Breast Cancer, Familial 3 | 8
Bronchiectasis 3 | 64
Carcinoma, Squamous Cell 3 | 110
Cholestasis 3 | 155
Coronary artery disease 3 | 268
Cowden disease 3 | 18
Craniofacial Abnormalities 3 | 151
Crohn's disease 3 | 321
Dermatitis 3 | 157
Endometriosis 3 | 540
Hereditary Breast and Ovarian Cancer Syndrome 3 | 14
Microcephaly 3 | 166
Multiple Sclerosis 3 | 540
Obesity 3 | 678
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Squamous cell carcinoma 3 | 129
Stomach Neoplasms 3 | 300
Werner syndrome 3 | 29
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
atypical teratoid/rhabdoid tumor 3 | 357
cystic fibrosis 3 | 1,696
hepatocellular carcinoma 3 | 547
hypopigmented skin patch 3 | 59
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
sonic hedgehog group medulloblastoma 3 | 467
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis and treatment for 6 months 3 | 409

Tissue

Digestive Tract 48 | 17,369
Endocrine System 48 | 18,159
Female tissues 48 | 17,400
Male tissues 48 | 17,142
Nervous System 48 | 16,725
Blood and immune system 47 | 16,909
Liver and Pancreas 47 | 16,750
Respiratory system 47 | 16,393
Skin and soft tissues 47 | 17,230
Urinary Tract 47 | 16,678
Cardiovascular System 44 | 15,192

Target Family

Non-IDG 30 | 12,091
Enzyme 10 | 4,145
Epigenetic 3 | 242
Kinase 3 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

response to ionizing radiation 48 | 48
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase RNF8 RNF8 Tbio Enzyme -1.80196 70.0 250
DNA repair protein XRCC3 XRCC3 Tbio Non-IDG -2.50791 314.0 414
MRN complex-interacting protein MRNIP Tbio Non-IDG 0.30 0.80 82
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.84388 738.4 199
Keratin, type I cytoskeletal 14 KRT14 Tbio Non-IDG -2.90790 721.6 780
DNA repair and recombination protein RAD54-like RAD54L Tbio Non-IDG -1.28409 19.0 161
Vitamin D 25-hydroxylase CYP2R1 Tbio Enzyme -1.96830 95.4 152
DNA topoisomerase 2-binding protein 1 TOPBP1 Tbio Enzyme -2.04312 118.0 230
ATP-binding cassette sub-family G member 5 ABCG5 Tbio Transporter -2.29380 189.0 123
Treslin TICRR Tbio Non-IDG -1.28917 24.4 28