Development Level

Tbio 26 | 11,445
Tchem 15 | 1,598
Tclin 8 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
decreased bone mineral content 2 | 151
decreased circulating alanine ... 2 | 47
decreased total body fat amoun... 2 | 207
increased total body fat amoun... 2 | 134
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 16
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased fasted circulating g... 1 | 65
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

ovarian cancer 38 | 8,520
Cancer 28 | 2,499
Carcinoma 28 | 11,493
psoriasis 28 | 6,694
lung cancer 21 | 4,740
osteosarcoma 21 | 7,950
medulloblastoma, large-cell 18 | 6,241
diabetes mellitus 17 | 1,728
ependymoma 16 | 4,679
glioblastoma 16 | 5,792
atypical teratoid / rhabdoid tumor 15 | 5,112
non-small cell lung cancer 15 | 2,890
Breast cancer 14 | 3,578
colon cancer 14 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
Hypertension 13 | 396
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
pancreatic cancer 13 | 2,398
pituitary cancer 13 | 1,972
tuberculosis 13 | 2,010
Autosomal recessive predisposition 12 | 1,442
lung adenocarcinoma 12 | 2,716
lung carcinoma 12 | 2,843
malignant mesothelioma 12 | 3,232
Vascular disease 11 | 319
invasive ductal carcinoma 11 | 2,951
Breast Neoplasms 10 | 445
Diabetes Mellitus, Non-Insulin-Dependent 10 | 145
Heart disease 10 | 306
Hypertensive disease 10 | 292
Mammary Neoplasms 10 | 425
Schizophrenia 10 | 1,160
Waldenstrons macroglobulinemia 10 | 765
adult high grade glioma 10 | 3,801
breast carcinoma 10 | 1,638
group 4 medulloblastoma 10 | 1,855
interstitial cystitis 10 | 2,312
Alzheimer's disease 9 | 658
Asthma 9 | 385
Depressive disorder 9 | 409
Multiple myeloma 9 | 1,332
Obesity 9 | 678
cystic fibrosis 9 | 1,696
ductal carcinoma in situ 9 | 1,745
group 3 medulloblastoma 9 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Brain Ischemia 8 | 110
Diabetes Mellitus, Type 2 8 | 142
Heart failure 8 | 162
Hyperglycemia 8 | 137
Kidney disease 8 | 430
Rheumatoid arthritis 8 | 1,191
oligodendroglioma 8 | 2,850
ulcerative colitis 8 | 1,819
Arthritis 7 | 290
Astrocytoma, Pilocytic 7 | 3,081
Diabetes Mellitus, Experimental 7 | 108
Myocardial Infarction 7 | 151
Reperfusion Injury 7 | 86
Status Epilepticus 7 | 98
Toxic encephalopathy 7 | 141
acute quadriplegic myopathy 7 | 1,158
aldosterone-producing adenoma 7 | 665
astrocytoma 7 | 1,146
fibroadenoma 7 | 559
Kidney cancer 6 | 2,613
Liver Cirrhosis, Experimental 6 | 769
Liver disease 6 | 237
Lung Neoplasms 6 | 232
Muscle Weakness 6 | 170
Neuropathy 6 | 261
Parkinson's disease 6 | 392
Prostatic Neoplasms 6 | 495
gastric cancer 6 | 459
primitive neuroectodermal tumor 6 | 3,035
Anemia 5 | 365
Atherosclerosis 5 | 291
Atopic dermatitis 5 | 952
Autistic Disorder 5 | 364
Colonic Neoplasms 5 | 142
Congestive heart failure 5 | 113
Down syndrome 5 | 499
Epilepsy 5 | 792
Fatigue 5 | 182
Hemangioma 5 | 69
Hepatomegaly 5 | 285
Mental Depression 5 | 333
Myocardial Ischemia 5 | 169
Myopathy 5 | 185
Nerve Degeneration 5 | 121
Osteoporosis 5 | 363
Seizures 5 | 596
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
adrenocortical carcinoma 5 | 1,428
gastric carcinoma 5 | 807
non primary Sjogren syndrome sicca 5 | 891
pancreatic carcinoma 5 | 562
urothelial carcinoma 5 | 318

Tissue

Blood and immune system 49 | 16,909
Digestive Tract 49 | 17,369
Endocrine System 49 | 18,159
Female tissues 49 | 17,400
Liver and Pancreas 49 | 16,750
Male tissues 49 | 17,142
Nervous System 49 | 16,725
Respiratory system 49 | 16,393
Skin and soft tissues 49 | 17,230
Urinary Tract 49 | 16,678
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 16 | 4,145
Kinase 6 | 634
Ion Channel 2 | 344
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

response to hydrogen peroxide 49 | 49
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase 24 STK24 Tchem Kinase -2.24110 132.9 243
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.08807 122.3 258
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Elongation factor 2 EEF2 Tchem Non-IDG -2.95619 938.4 363
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.84388 738.4 199
Fos-related antigen 1 FOSL1 Tbio Transcription Factor -2.39870 235.8 243
Transient receptor potential cation channel subfamily A member 1 TRPA1 Tclin Ion Channel -2.88003 848.3 185
Haptoglobin HP Tbio Non-IDG -3.65404 4337.6 791
Nuclear receptor subfamily 4 group A member 3 NR4A3 Tbio Nuclear Receptor -2.02752 112.7 289
Guanine nucleotide-binding protein G(o) subunit alpha GNAO1 Tbio Non-IDG -2.24331 158.7 195