Development Level

Tbio 30 | 11,445
Tchem 7 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
decreased circulating triglyce... 1 | 79
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
polycystic kidney 1 | 15
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 26 | 11,493
ovarian cancer 24 | 8,520
glioblastoma 20 | 5,792
Cancer 18 | 2,499
psoriasis 18 | 6,694
atypical teratoid / rhabdoid tumor 17 | 5,112
ependymoma 17 | 4,679
lung cancer 17 | 4,740
osteosarcoma 17 | 7,950
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
adult high grade glioma 13 | 3,801
invasive ductal carcinoma 13 | 2,951
subependymal giant cell astrocytoma 13 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
lung carcinoma 12 | 2,843
malignant mesothelioma 12 | 3,232
medulloblastoma, large-cell 12 | 6,241
Astrocytoma, Pilocytic 11 | 3,081
interstitial cystitis 11 | 2,312
Breast cancer 10 | 3,578
lung adenocarcinoma 10 | 2,716
oligodendroglioma 10 | 2,850
pituitary cancer 10 | 1,972
Autosomal recessive predisposition 9 | 1,442
diabetes mellitus 9 | 1,728
non-small cell lung cancer 9 | 2,890
pancreatic cancer 9 | 2,398
astrocytic glioma 8 | 2,597
colon cancer 8 | 1,478
gastric carcinoma 8 | 807
group 3 medulloblastoma 8 | 4,104
Pick disease 7 | 1,894
adrenocortical carcinoma 7 | 1,428
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
primitive neuroectodermal tumor 7 | 3,035
Schizophrenia 6 | 1,160
Vascular disease 6 | 319
cystic fibrosis 6 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
ulcerative colitis 6 | 1,819
Atopic dermatitis 5 | 952
Heart disease 5 | 306
Hypertension 5 | 396
Liver Cirrhosis, Experimental 5 | 769
Lung disease 5 | 142
Multiple myeloma 5 | 1,332
Obesity 5 | 678
active ulcerative colitis 5 | 764
astrocytoma 5 | 1,146
cutaneous lupus erythematosus 5 | 1,057
fibroadenoma 5 | 559
sonic hedgehog group medulloblastoma 5 | 467
Anemia 4 | 365
Arthritis 4 | 290
Cataract 4 | 297
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Endometriosis 4 | 540
Glaucoma 4 | 239
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
group 4 medulloblastoma 4 | 1,855
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
nephrosclerosis 4 | 333
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
Alcoholic Intoxication, Chronic 3 | 289
Anteverted nostril 3 | 191
Asthma 3 | 385
Depressive disorder 3 | 409
Diabetes Mellitus, Experimental 3 | 108
Kidney cancer 3 | 2,613
Lens Opacities 3 | 231
Myocardial Infarction 3 | 151
Osteoporosis 3 | 363
Prader-Willi syndrome 3 | 48
Seizures 3 | 596
Vomiting 3 | 116
Waldenstrons macroglobulinemia 3 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
facioscapulohumeral dystrophy 3 | 288
limb girdle muscular dystrophy 2A 3 | 213
non diabetic and post-ischemic heart failure 3 | 200
non primary Sjogren syndrome sicca 3 | 891
periodontitis 3 | 293
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Broad flat nasal bridge 2 | 236
Curvature of spine 2 | 282
Delayed bone age 2 | 136
Nasal bridge wide 2 | 236
Short nose 2 | 132
Small nose 2 | 132
Strabismus 2 | 270
Ventricular Septal Defects 2 | 119
tuberculosis and treatment for 3 months 2 | 179

Tissue

Digestive Tract 40 | 17,369
Endocrine System 39 | 18,159
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Blood and immune system 37 | 16,909
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Respiratory system 37 | 16,393
Cardiovascular System 36 | 15,192
Female tissues 36 | 17,400
Nervous System 36 | 16,725

Target Family

Non-IDG 16 | 12,091
Enzyme 14 | 4,145
Transcription Factor 6 | 1,400
GPCR 2 | 408
Kinase 2 | 634

GO Process

response to hormone 40 | 40
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein C2 FOXC2 Tbio Transcription Factor -2.23435 187.0 419
RNA-binding protein 14 RBM14 Tbio Non-IDG -2.10043 124.7 168
Sorbitol dehydrogenase SORD Tchem Enzyme -2.18880 132.4 347
NADP-dependent malic enzyme ME1 Tchem Non-IDG -1.98857 92.8 234
E3 SUMO-protein ligase PIAS3 PIAS3 Tbio Transcription Factor -1.74449 53.4 174
Alpha-1A adrenergic receptor ADRA1A Tclin GPCR -2.18682 155.5 236
Metalloreductase STEAP2 STEAP2 Tbio Enzyme -1.78852 56.5 154
Cytochrome b-c1 complex subunit Rieske, mitochondrial UQCRFS1 Tbio Non-IDG -2.12377 231.9 211
Four and a half LIM domains protein 2 FHL2 Tbio Non-IDG -2.60042 385.8 253
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631