Development Level

Tbio 43 | 11,445
Tchem 21 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
decreased circulating glucose ... 4 | 126
decreased vertical activity 4 | 208
abnormal embryo size 3 | 220
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
increased bone mineral content 3 | 108
increased circulating calcium ... 3 | 34
increased lean body mass 3 | 172
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
decreased circulating insulin ... 2 | 76
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal bone structure 1 | 187
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent seminal vesicle 1 | 4
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating glycerol... 1 | 16
decreased granulocyte number 1 | 6
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
female infertility 1 | 60
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased total retina thickne... 1 | 4
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
prolonged RR interval 1 | 8
small testis 1 | 58
small uterus 1 | 3
thick ventricular wall 1 | 7
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

Carcinoma 40 | 11,493
ovarian cancer 33 | 8,520
osteosarcoma 30 | 7,950
psoriasis 30 | 6,694
medulloblastoma, large-cell 28 | 6,241
diabetes mellitus 27 | 1,728
Cancer 26 | 2,499
glioblastoma 26 | 5,792
group 3 medulloblastoma 21 | 4,104
atypical teratoid / rhabdoid tumor 20 | 5,112
ependymoma 20 | 4,679
lung cancer 20 | 4,740
malignant mesothelioma 18 | 3,232
Breast cancer 17 | 3,578
Obesity 17 | 678
adult high grade glioma 17 | 3,801
lung carcinoma 17 | 2,843
Astrocytoma, Pilocytic 15 | 3,081
Autosomal recessive predisposition 15 | 1,442
invasive ductal carcinoma 15 | 2,951
pancreatic cancer 15 | 2,398
oligodendroglioma 14 | 2,850
pituitary cancer 14 | 1,972
Seizures 13 | 596
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
primitive neuroectodermal tumor 13 | 3,035
Liver Cirrhosis, Experimental 12 | 769
breast carcinoma 12 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
subependymal giant cell astrocytoma 12 | 2,287
Atopic dermatitis 11 | 952
Epilepsy 11 | 792
Hypertension 11 | 396
Schizophrenia 11 | 1,160
lung adenocarcinoma 11 | 2,716
Hyperglycemia 10 | 137
Kidney cancer 10 | 2,613
Prostatic Neoplasms 10 | 495
non-small cell lung cancer 10 | 2,890
Diabetes Mellitus, Non-Insulin-Dependent 9 | 145
Diabetes Mellitus, Type 2 9 | 142
Hypertensive disease 9 | 292
Kidney disease 9 | 430
Pick disease 9 | 1,894
Rheumatoid arthritis 9 | 1,191
Type 2 diabetes mellitus 9 | 272
astrocytic glioma 9 | 2,597
astrocytoma 9 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
dermatomyositis 9 | 966
ulcerative colitis 9 | 1,819
Atherosclerosis 8 | 291
Heart disease 8 | 306
Lung Neoplasms 8 | 232
Muscle hypotonia 8 | 571
Vascular disease 8 | 319
acute quadriplegic myopathy 8 | 1,158
adrenocortical carcinoma 8 | 1,428
ductal carcinoma in situ 8 | 1,745
gastric carcinoma 8 | 807
Adenoma 7 | 167
Big calvaria 7 | 147
Carcinoma, Hepatocellular 7 | 228
Diabetes Mellitus, Experimental 7 | 108
Down syndrome 7 | 499
Increased head circumference 7 | 147
Increased size of cranium 7 | 147
Increased size of skull 7 | 147
Lethargy 7 | 77
Liver carcinoma 7 | 240
Liver disease 7 | 237
interstitial cystitis 7 | 2,312
juvenile dermatomyositis 7 | 1,187
non primary Sjogren syndrome sicca 7 | 891
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primary pancreatic ductal adenocarcinoma 7 | 1,109
Bipolar Disorder 6 | 666
Coronary artery disease 6 | 268
Duchenne muscular dystrophy 6 | 601
Dysarthria 6 | 192
Hyperinsulinism 6 | 133
Lipid metabolism disorder 6 | 114
Muscle Spasticity 6 | 195
Myocardial Infarction 6 | 151
Optic Atrophy 6 | 242
Short stature 6 | 531
active ulcerative colitis 6 | 764
cystic fibrosis 6 | 1,696
nasopharyngeal carcinoma 6 | 1,058
tuberculosis 6 | 2,010
Becker muscular dystrophy 5 | 191
Hypoglycemia 5 | 152
Myopathy 5 | 185
Secondary physiologic amenorrhea 5 | 32
Unipolar Depression 5 | 250
colon cancer 5 | 1,478
fibroadenoma 5 | 559
medulloblastoma 5 | 720
spina bifida 5 | 1,074

Tissue

Digestive Tract 66 | 17,369
Endocrine System 66 | 18,159
Female tissues 64 | 17,400
Skin and soft tissues 64 | 17,230
Liver and Pancreas 63 | 16,750
Nervous System 62 | 16,725
Urinary Tract 62 | 16,678
Blood and immune system 61 | 16,909
Male tissues 61 | 17,142
Respiratory system 61 | 16,393
Cardiovascular System 57 | 15,192

Target Family

Non-IDG 32 | 12,091
Enzyme 11 | 4,145
Kinase 9 | 634
Transcription Factor 8 | 1,400
Nuclear Receptor 3 | 48
Transporter 2 | 473
GPCR 1 | 408

GO Process

response to glucose 66 | 66
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycerol-3-phosphate acyltransferase 1, mitochondrial GPAM Tbio Enzyme -1.93041 83.4 177
Translation initiation factor eIF-2B subunit delta EIF2B4 Tbio Non-IDG -1.06082 11.3 145
Zinc transporter 8 SLC30A8 Tbio Transporter -2.20313 168.0 122
Collagen alpha-2(VI) chain COL6A2 Tbio Non-IDG -1.80531 59.2 151
Sterile alpha and TIR motif-containing protein 1 SARM1 Tbio Non-IDG -2.22753 163.9 159
Pyruvate kinase PKLR PKLR Tbio Kinase -2.37549 231.1 391
SID1 transmembrane family member 2 SIDT2 Tbio Non-IDG -1.01249 13.0 81
Transcription factor MafA MAFA Tbio Transcription Factor -1.36099 23.0 195
Sestrin-2 SESN2 Tbio Non-IDG -1.88129 92.6 176
Thioredoxin reductase-like selenoprotein T SELENOT Tbio Non-IDG -1.36965 25.6 0