Development Level

Tbio 35 | 11,445
Tchem 18 | 1,598
Tclin 8 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
decreased bone mineral density 3 | 126
preweaning lethality, complete... 3 | 979
abnormal bone structure 2 | 187
abnormal sleep behavior 2 | 70
cataract 2 | 92
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 31
decreased vertical activity 2 | 208
impaired glucose tolerance 2 | 75
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal lens morphology 1 | 81
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased circulating alanine ... 1 | 47
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
increased circulating magnesiu... 1 | 10
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

psoriasis 34 | 6,694
Carcinoma 33 | 11,493
medulloblastoma, large-cell 29 | 6,241
Cancer 27 | 2,499
ovarian cancer 26 | 8,520
glioblastoma 24 | 5,792
lung cancer 24 | 4,740
atypical teratoid / rhabdoid tumor 22 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
lung adenocarcinoma 21 | 2,716
interstitial cystitis 20 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
malignant mesothelioma 20 | 3,232
non-small cell lung cancer 20 | 2,890
invasive ductal carcinoma 19 | 2,951
Breast cancer 18 | 3,578
diabetes mellitus 18 | 1,728
Astrocytoma, Pilocytic 17 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
osteosarcoma 17 | 7,950
Rheumatoid arthritis 16 | 1,191
ependymoma 16 | 4,679
lung carcinoma 16 | 2,843
cystic fibrosis 15 | 1,696
pancreatic cancer 15 | 2,398
ulcerative colitis 15 | 1,819
Asthma 14 | 385
Autosomal recessive predisposition 14 | 1,442
Obesity 14 | 678
Schizophrenia 14 | 1,160
tuberculosis 14 | 2,010
adult high grade glioma 13 | 3,801
breast carcinoma 13 | 1,638
Liver Cirrhosis, Experimental 12 | 769
Prostatic Neoplasms 12 | 495
group 3 medulloblastoma 12 | 4,104
pituitary cancer 12 | 1,972
primitive neuroectodermal tumor 12 | 3,035
Alzheimer's disease 11 | 658
Hypertension 11 | 396
Kidney disease 11 | 430
Multiple Sclerosis 11 | 540
Myocardial Infarction 11 | 151
adrenocortical carcinoma 11 | 1,428
ductal carcinoma in situ 11 | 1,745
nasopharyngeal carcinoma 11 | 1,058
Arthritis 10 | 290
Bipolar Disorder 10 | 666
Depressive disorder 10 | 409
Diarrhea 10 | 253
Fever 10 | 138
Hypersensitivity reaction type II disease 10 | 253
Inflammation 10 | 120
Kidney cancer 10 | 2,613
colon cancer 10 | 1,478
oligodendroglioma 10 | 2,850
Atherosclerosis 9 | 291
Brain disease 9 | 96
Breast Neoplasms 9 | 445
Diabetes Mellitus, Non-Insulin-Dependent 9 | 145
Endometriosis 9 | 540
Hyperalgesia 9 | 83
Hyperglycemia 9 | 137
Hypertensive disease 9 | 292
Mammary Neoplasms 9 | 425
Mental Depression 9 | 333
Seizures 9 | 596
fibroadenoma 9 | 559
group 4 medulloblastoma 9 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Anemia 8 | 365
Arthritis, Rheumatoid 8 | 174
Atopic dermatitis 8 | 952
Autistic Disorder 8 | 364
Cerebrovascular disease 8 | 238
Colonic Neoplasms 8 | 142
Diabetes Mellitus, Type 2 8 | 142
Disease Models, Animal 8 | 155
Liver disease 8 | 237
Parkinson's disease 8 | 392
Toxic encephalopathy 8 | 141
subependymal giant cell astrocytoma 8 | 2,287
Colorectal Neoplasms 7 | 243
Coronary artery disease 7 | 268
Heart disease 7 | 306
Liver Cirrhosis 7 | 181
Major Depressive Disorder 7 | 301
Multiple myeloma 7 | 1,332
Myocardial Ischemia 7 | 169
Neuropathy 7 | 261
Osteoporosis 7 | 363
Short stature 7 | 531
Stomach Neoplasms 7 | 300
Unipolar Depression 7 | 250
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
gastric cancer 7 | 459
pediatric high grade glioma 7 | 1,064
primary pancreatic ductal adenocarcinoma 7 | 1,109

Tissue

Endocrine System 60 | 18,159
Liver and Pancreas 59 | 16,750
Digestive Tract 58 | 17,369
Urinary Tract 58 | 16,678
Blood and immune system 56 | 16,909
Female tissues 56 | 17,400
Nervous System 56 | 16,725
Skin and soft tissues 56 | 17,230
Respiratory system 55 | 16,393
Male tissues 54 | 17,142
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 31 | 12,091
Enzyme 23 | 4,145
GPCR 3 | 408
Transcription Factor 2 | 1,400
Kinase 1 | 634
Transporter 1 | 473

GO Process

response to glucocorticoid 61 | 61
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histamine N-methyltransferase HNMT Tchem Enzyme -2.88300 757.5 234
Mitochondrial uncoupling protein 3 UCP3 Tbio Non-IDG -2.74050 585.4 181
ATP-binding cassette sub-family A member 3 ABCA3 Tbio Transporter -2.25972 187.7 32
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.08807 122.3 258
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Probable G-protein coupled receptor 83 GPR83 Tchem GPCR -2.39015 221.5 272
Thymidylate synthase TYMS Tclin Enzyme -2.93426 732.0 733
ADM ADM Tbio Non-IDG -3.27504 1889.0 381
Delta-aminolevulinic acid dehydratase ALAD Tbio Enzyme -3.02024 1068.6 166