Development Level

Tbio 4 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal clavicle morphology 1 | 6
abnormal seminal vesicle morph... 1 | 114
cataract 1 | 92
decreased circulating alkaline... 1 | 46
decreased circulating glycerol... 1 | 16
decreased circulating total pr... 1 | 49
decreased heart weight 1 | 27
enlarged heart 1 | 210
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92

Disease

Cancer 7 | 2,499
Carcinoma 6 | 11,493
Depressive disorder 5 | 409
Epilepsy 5 | 792
ovarian cancer 4 | 8,520
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Breast cancer 3 | 3,578
Disease Models, Animal 3 | 155
Downward slant of palpebral fissure 3 | 158
Fetal Growth Retardation 3 | 189
Heart disease 3 | 306
Heart failure 3 | 162
Hypoplastic mandible condyle 3 | 275
Kidney disease 3 | 430
Liver Cirrhosis, Experimental 3 | 769
Lung Neoplasms 3 | 232
Lung disease 3 | 142
Major Depressive Disorder 3 | 301
Mammary Neoplasms 3 | 425
Mandibular hypoplasia 3 | 275
Mental Depression 3 | 333
Micrognathism 3 | 275
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
Seizures 3 | 596
Skin Neoplasms 3 | 69
Thin lips 3 | 49
Vascular disease 3 | 319
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
ulcerative colitis 3 | 1,819
Abnormal skeletal development 2 | 60
Abnormality of the metaphyses 2 | 48
Adenoma 2 | 167
Adult onset 2 | 82
Anemia 2 | 365
Big calvaria 2 | 147
Bilateral fifth finger clinodactyly 2 | 110
Blepharoptosis 2 | 231
Brachydactyly 2 | 156
Brain disease 2 | 96
Broad flat nasal bridge 2 | 236
Cardiomegaly 2 | 116
Cardiovascular Diseases 2 | 59
Cerebrovascular disease 2 | 238
Colorectal Neoplasms 2 | 243
Concave bridge of nose 2 | 195
Curvature of little finger 2 | 110
Depressed nasal root/bridge 2 | 195
Dysarthria 2 | 192
Exophthalmos 2 | 112
Hyperinsulinism 2 | 133
Hyperreflexia 2 | 209
Hypertension 2 | 396
Hypoplasia of the maxilla 2 | 66
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Infantile onset 2 | 238
Inflammation 2 | 120
Inflammatory bowel disease 2 | 151
Late tooth eruption 2 | 61
Lipid metabolism disorder 2 | 114
Long narrow head 2 | 75
Maxillary retrognathia 2 | 66
Melanoma 2 | 711
Microstomia 2 | 78
Mood Disorders 2 | 184
Multiple Sclerosis 2 | 540
Muscle Weakness 2 | 170
Muscular atrophy 2 | 71
Myocardial Infarction 2 | 151
Myopia 2 | 176
Narrow cranium shape 2 | 75
Narrow head shape 2 | 75
Narrow skull shape 2 | 75
Nasal bridge wide 2 | 236
Osteochondrodysplasias 2 | 72
Progressive disorder 2 | 142
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Right atrial isomerism 2 | 29
Sparse hair 2 | 59
Stomach Neoplasms 2 | 300
Thin, sparse hair 2 | 59
Thrombocytopenia 2 | 197
Turridolichocephaly 2 | 75
atypical teratoid/rhabdoid tumor 2 | 357

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192
Nervous System 8 | 16,725

Target Family

Non-IDG 4 | 12,091
Ion Channel 2 | 344
Kinase 2 | 634
Enzyme 1 | 4,145

GO Process

response to fluid shear stress 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polycystin-1 PKD1 Tbio Non-IDG -2.60276 379.9 123
Nitric oxide synthase, endothelial NOS3 Tchem Enzyme -3.96497 9525.3 1195
Granulocyte-macrophage colony-stimulating factor CSF2 Tbio Non-IDG -3.91682 8450.3 1272
P2X purinoceptor 7 P2RX7 Tchem Ion Channel -2.96940 962.2 272
Cbp/p300-interacting transactivator 2 CITED2 Tbio Non-IDG -2.07760 134.8 167
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.36734 20160.1 3565
P2X purinoceptor 4 P2RX4 Tchem Ion Channel -2.49038 314.8 181
Platelet-derived growth factor receptor beta PDGFRB Tclin Kinase -2.89315 712.3 1390
Gap junction alpha-1 protein GJA1 Tbio Non-IDG -3.59195 4122.5 889