Development Level

Tbio 55 | 11,445
Tchem 26 | 1,598
Tclin 24 | 613

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 6 | 499
decreased vertical activity 3 | 208
abnormal epididymis morphology 2 | 42
decreased bone mineral content 2 | 151
increased startle reflex 2 | 112
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal lens morphology 1 | 81
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
absent testes 1 | 6
cataract 1 | 92
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased CD4-positive, alpha ... 1 | 4
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased heart left ventricle... 1 | 4
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
male infertility 1 | 123
prolonged RR interval 1 | 8

Disease

psoriasis 66 | 6,694
Carcinoma 63 | 11,493
Cancer 59 | 2,499
ovarian cancer 56 | 8,520
glioblastoma 51 | 5,792
osteosarcoma 45 | 7,950
lung cancer 42 | 4,740
atypical teratoid / rhabdoid tumor 41 | 5,112
Schizophrenia 40 | 1,160
ependymoma 40 | 4,679
medulloblastoma, large-cell 40 | 6,241
adult high grade glioma 37 | 3,801
Astrocytoma, Pilocytic 33 | 3,081
invasive ductal carcinoma 33 | 2,951
group 3 medulloblastoma 29 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
oligodendroglioma 29 | 2,850
Breast cancer 28 | 3,578
diabetes mellitus 28 | 1,728
Obesity 27 | 678
lung adenocarcinoma 27 | 2,716
primitive neuroectodermal tumor 26 | 3,035
Bipolar Disorder 25 | 666
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
Alcoholic Intoxication, Chronic 24 | 289
astrocytic glioma 24 | 2,597
ductal carcinoma in situ 23 | 1,745
non-small cell lung cancer 23 | 2,890
tuberculosis 23 | 2,010
Autosomal recessive predisposition 22 | 1,442
Depressive disorder 22 | 409
lung carcinoma 22 | 2,843
malignant mesothelioma 22 | 3,232
interstitial cystitis 21 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
Asthma 20 | 385
Hypertension 20 | 396
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
pituitary cancer 19 | 1,972
Mental Depression 18 | 333
breast carcinoma 18 | 1,638
Alzheimer's disease 17 | 658
Prostatic Neoplasms 17 | 495
subependymal giant cell astrocytoma 17 | 2,287
ulcerative colitis 17 | 1,819
Hypertensive disease 16 | 292
Kidney disease 16 | 430
Liver Cirrhosis, Experimental 16 | 769
Major Depressive Disorder 16 | 301
Pick disease 16 | 1,894
adrenocortical carcinoma 16 | 1,428
colon cancer 16 | 1,478
pancreatic cancer 16 | 2,398
Atopic dermatitis 15 | 952
Breast Neoplasms 15 | 445
Mammary Neoplasms 15 | 425
cystic fibrosis 15 | 1,696
group 4 medulloblastoma 15 | 1,855
Autistic Disorder 14 | 364
Endometriosis 14 | 540
Multiple myeloma 14 | 1,332
Parkinson's disease 14 | 392
Seizures 14 | 596
Toxic encephalopathy 14 | 141
nasopharyngeal carcinoma 14 | 1,058
Alcohol dependence 13 | 107
Atherosclerosis 13 | 291
Kidney cancer 13 | 2,613
Liver disease 13 | 237
Mood Disorders 12 | 184
Multiple Sclerosis 12 | 540
Rheumatoid arthritis 12 | 1,191
Stomach Neoplasms 12 | 300
Unipolar Depression 12 | 250
aldosterone-producing adenoma 12 | 665
astrocytoma 12 | 1,146
cutaneous lupus erythematosus 12 | 1,057
fibroadenoma 12 | 559
Cerebrovascular disease 11 | 238
Chemical and Drug Induced Liver Injury 11 | 195
Epilepsy 11 | 792
Hypersensitivity reaction type II disease 11 | 253
Melanoma 11 | 711
Vascular disease 11 | 319
Waldenstrons macroglobulinemia 11 | 765
Anemia 10 | 365
Arthritis 10 | 290
Diabetes Mellitus, Non-Insulin-Dependent 10 | 145
Heart disease 10 | 306
Heart failure 10 | 162
Hyperglycemia 10 | 137
Inflammation 10 | 120
Osteoporosis 10 | 363
Pain 10 | 103
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
esophageal adenocarcinoma 10 | 737
juvenile dermatomyositis 10 | 1,187
non primary Sjogren syndrome sicca 10 | 891
Attention deficit hyperactivity disorder 9 | 278
acute quadriplegic myopathy 9 | 1,158

Tissue

Digestive Tract 102 | 17,369
Endocrine System 102 | 18,159
Skin and soft tissues 102 | 17,230
Female tissues 100 | 17,400
Blood and immune system 99 | 16,909
Liver and Pancreas 97 | 16,750
Male tissues 97 | 17,142
Nervous System 97 | 16,725
Respiratory system 95 | 16,393
Urinary Tract 95 | 16,678
Cardiovascular System 85 | 15,192

Target Family

Non-IDG 47 | 12,091
Enzyme 31 | 4,145
Ion Channel 7 | 344
Kinase 7 | 634
GPCR 6 | 408
Transcription Factor 2 | 1,400
Transporter 2 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GO Process

response to ethanol 105 | 105
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alcohol dehydrogenase 6 ADH6 Tbio Enzyme -1.84121 71.7 117
Potassium voltage-gated channel subfamily C member 2 KCNC2 Tclin Ion Channel -1.45272 28.7 178
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.40865 2530.3 252
Methylated-DNA--protein-cysteine methyltransferase MGMT Tchem Enzyme -3.13356 1426.9 560
Neuronal acetylcholine receptor subunit beta-2 CHRNB2 Tclin Ion Channel -1.62448 37.6 174
Histone-lysine N-methyltransferase SETD7 SETD7 Tchem Epigenetic -2.13644 139.8 343
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
Acetoacetyl-CoA synthetase AACS Tbio Enzyme -2.09428 127.1 97
Alcohol dehydrogenase class 4 mu/sigma chain ADH7 Tchem Enzyme -2.18765 159.0 243