Development Level

Tbio 39 | 11,445
Tchem 15 | 1,598
Tclin 9 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal behavior 3 | 298
decreased bone mineral content 3 | 151
abnormal bone structure 2 | 187
abnormal pericardium morpholog... 2 | 26
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 50
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased circulating bilirubi... 2 | 16
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal clavicle morphology 1 | 6
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal fibula morphology 1 | 2
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 10
abnormal scapula morphology 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
absent mammary gland 1 | 1
absent pinna reflex 1 | 23
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased skeletal muscle mass 1 | 1
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
fusion of vertebral arches 1 | 7
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28
increased kidney weight 1 | 6
increased leukocyte cell numbe... 1 | 47
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small heart 1 | 10
small kidney 1 | 16
small ovary 1 | 1
small spleen 1 | 19
small uterus 1 | 3
thin skin 1 | 2
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 37 | 11,493
Cancer 36 | 2,499
ovarian cancer 31 | 8,520
psoriasis 31 | 6,694
glioblastoma 29 | 5,792
osteosarcoma 27 | 7,950
lung cancer 23 | 4,740
medulloblastoma, large-cell 23 | 6,241
ependymoma 22 | 4,679
malignant mesothelioma 22 | 3,232
Breast cancer 21 | 3,578
atypical teratoid / rhabdoid tumor 21 | 5,112
diabetes mellitus 21 | 1,728
Autosomal recessive predisposition 20 | 1,442
lung carcinoma 20 | 2,843
non-small cell lung cancer 20 | 2,890
Astrocytoma, Pilocytic 19 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
adult high grade glioma 17 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
lung adenocarcinoma 16 | 2,716
pancreatic cancer 16 | 2,398
Schizophrenia 15 | 1,160
group 3 medulloblastoma 14 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
invasive ductal carcinoma 14 | 2,951
oligodendroglioma 13 | 2,850
Bipolar Disorder 12 | 666
Kidney cancer 12 | 2,613
Obesity 12 | 678
cystic fibrosis 12 | 1,696
ductal carcinoma in situ 12 | 1,745
interstitial cystitis 12 | 2,312
Coronary artery disease 11 | 268
Depressive disorder 11 | 409
Liver Cirrhosis, Experimental 11 | 769
Short stature 11 | 531
primitive neuroectodermal tumor 11 | 3,035
ulcerative colitis 11 | 1,819
Epilepsy 10 | 792
Hypertension 10 | 396
Hypertensive disease 10 | 292
Seizures 10 | 596
astrocytic glioma 10 | 2,597
pituitary cancer 10 | 1,972
Atherosclerosis 9 | 291
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
Prostatic Neoplasms 9 | 495
Stomach Neoplasms 9 | 300
Vascular disease 9 | 319
Arthritis 8 | 290
Hepatomegaly 8 | 285
Liver disease 8 | 237
Lung Neoplasms 8 | 232
Mental Depression 8 | 333
Osteoporosis 8 | 363
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
group 4 medulloblastoma 8 | 1,855
pediatric high grade glioma 8 | 1,064
Adenocarcinoma 7 | 122
Adenoma 7 | 167
Anemia 7 | 365
Dull intelligence 7 | 645
Fetal Growth Retardation 7 | 189
Heart disease 7 | 306
Infant, Small for Gestational Age 7 | 176
Inflammation 7 | 120
Intellectual disability 7 | 1,016
Intrauterine retardation 7 | 176
Kidney disease 7 | 430
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Mood Disorders 7 | 184
Polycystic ovary syndrome 7 | 360
Poor school performance 7 | 645
astrocytoma 7 | 1,146
juvenile dermatomyositis 7 | 1,187
Alzheimer's disease 6 | 658
Asthma 6 | 385
Atopic dermatitis 6 | 952
Byzanthine arch palate 6 | 194
Cognitive delay 6 | 608
Failure to gain weight 6 | 365
Glaucoma 6 | 239
Global developmental delay 6 | 608
Major Depressive Disorder 6 | 301
Mental and motor retardation 6 | 608
Muscle hypotonia 6 | 571
Neoplasm Invasiveness 6 | 161
Pediatric failure to thrive 6 | 365
Pick disease 6 | 1,894
Ventricular Septal Defects 6 | 119
esophageal adenocarcinoma 6 | 737
fibroadenoma 6 | 559
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primary pancreatic ductal adenocarcinoma 6 | 1,109
subependymal giant cell astrocytoma 6 | 2,287

Tissue

Endocrine System 61 | 18,159
Female tissues 59 | 17,400
Liver and Pancreas 59 | 16,750
Skin and soft tissues 59 | 17,230
Digestive Tract 58 | 17,369
Nervous System 58 | 16,725
Urinary Tract 58 | 16,678
Blood and immune system 57 | 16,909
Male tissues 57 | 17,142
Respiratory system 57 | 16,393
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 31 | 12,091
Enzyme 14 | 4,145
Kinase 5 | 634
Transcription Factor 5 | 1,400
Epigenetic 2 | 242
GPCR 2 | 408
Nuclear Receptor 2 | 48
Transporter 2 | 473

GO Process

response to estrogen 63 | 63
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
Signal transducer CD24 CD24 Tbio Non-IDG 0.00000 0
Arylsulfatase B ARSB Tbio Enzyme -2.51626 314.5 216
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.84388 738.4 199
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Keratin, type I cytoskeletal 19 KRT19 Tbio Non-IDG -3.23530 1627.1 1789
Insulin-like growth factor-binding protein 2 IGFBP2 Tchem Non-IDG -2.93237 835.0 335
Retinoblastoma-binding protein 5 RBBP5 Tbio Non-IDG -1.40059 20.2 180
Set1/Ash2 histone methyltransferase complex subunit ASH2 ASH2L Tbio Enzyme -1.56543 33.7 261