Development Level

Tbio 48 | 11,651
Tchem 30 | 1,388
Tclin 16 | 612

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

increased total body fat amoun... 5 | 134
preweaning lethality, incomple... 5 | 499
decreased bone mineral content 4 | 151
preweaning lethality, complete... 4 | 979
decreased lean body mass 3 | 135
decreased total body fat amoun... 3 | 207
increased bone mineral content 3 | 108
abnormal seminal vesicle morph... 2 | 114
decreased circulating glucose ... 2 | 126
decreased fasted circulating g... 2 | 65
enlarged heart 2 | 210
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal esophagus morphology 1 | 5
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal pancreas morphology 1 | 13
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin coloration 1 | 25
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
absent lymph nodes 1 | 3
absent testes 1 | 6
anophthalmia 1 | 33
athymia 1 | 2
cataract 1 | 92
corneal opacity 1 | 32
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased vertical activity 1 | 208
edema 1 | 59
enlarged spleen 1 | 41
female infertility 1 | 60
fused cornea and lens 1 | 5
fusion of vertebral arches 1 | 7
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased body weight 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
iris synechia 1 | 3
lordosis 1 | 1
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 67 | 11,493
ovarian cancer 62 | 8,520
Cancer 56 | 2,499
psoriasis 54 | 6,694
glioblastoma 45 | 5,792
lung cancer 45 | 4,740
medulloblastoma, large-cell 44 | 6,241
osteosarcoma 41 | 7,950
atypical teratoid / rhabdoid tumor 40 | 5,112
Breast cancer 38 | 3,578
invasive ductal carcinoma 35 | 2,951
malignant mesothelioma 33 | 3,232
ependymoma 32 | 4,679
breast carcinoma 31 | 1,638
lung adenocarcinoma 30 | 2,716
Schizophrenia 29 | 1,160
non-small cell lung cancer 29 | 2,890
Prostatic Neoplasms 28 | 495
adult high grade glioma 28 | 3,801
pancreatic cancer 28 | 2,398
lung carcinoma 27 | 2,843
primitive neuroectodermal tumor 27 | 3,035
Autosomal recessive predisposition 26 | 1,442
diabetes mellitus 25 | 1,728
group 3 medulloblastoma 25 | 4,104
oligodendroglioma 25 | 2,850
Astrocytoma, Pilocytic 24 | 3,081
ductal carcinoma in situ 24 | 1,745
interstitial cystitis 24 | 2,312
Breast Neoplasms 23 | 445
Mammary Neoplasms 23 | 425
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
cystic fibrosis 21 | 1,696
pituitary cancer 21 | 1,972
Hypertension 20 | 396
Kidney cancer 20 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
Depressive disorder 19 | 409
Liver Cirrhosis, Experimental 19 | 769
Obesity 19 | 678
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
ulcerative colitis 19 | 1,819
subependymal giant cell astrocytoma 18 | 2,287
tuberculosis 18 | 2,010
Endometriosis 17 | 540
astrocytoma 17 | 1,146
Lung Neoplasms 16 | 232
nasopharyngeal carcinoma 16 | 1,058
Asthma 15 | 385
Atopic dermatitis 15 | 952
Mental Depression 15 | 333
adrenocortical carcinoma 15 | 1,428
colon cancer 15 | 1,478
juvenile dermatomyositis 15 | 1,187
Bipolar Disorder 14 | 666
Hypertensive disease 14 | 292
Short stature 14 | 531
Vascular disease 14 | 319
group 4 medulloblastoma 14 | 1,855
Adenocarcinoma 13 | 122
Alcoholic Intoxication, Chronic 13 | 289
Atherosclerosis 13 | 291
Heart disease 13 | 306
Kidney disease 13 | 430
Liver disease 13 | 237
Seizures 13 | 596
acute quadriplegic myopathy 13 | 1,158
astrocytic glioma 13 | 2,597
Autistic Disorder 12 | 364
Carcinoma, Hepatocellular 12 | 228
Liver carcinoma 12 | 240
fibroadenoma 12 | 559
Duchenne muscular dystrophy 11 | 601
Intellectual disability 11 | 1,016
Mood Disorders 11 | 184
Osteoporosis 11 | 363
Stomach Neoplasms 11 | 300
esophageal adenocarcinoma 11 | 737
gastric carcinoma 11 | 807
Alzheimer's disease 10 | 658
Major Depressive Disorder 10 | 301
Myocardial Infarction 10 | 151
Neoplasm Metastasis 10 | 168
Rheumatoid arthritis 10 | 1,191
Squamous cell carcinoma 10 | 129
pediatric high grade glioma 10 | 1,064
Cerebrovascular disease 9 | 238
Cognitive delay 9 | 608
Coronary artery disease 9 | 268
Diabetes Mellitus, Non-Insulin-Dependent 9 | 145
Diabetes Mellitus, Type 2 9 | 142
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
Multiple myeloma 9 | 1,332
aldosterone-producing adenoma 9 | 665
medulloblastoma 9 | 720
primary Sjogren syndrome 9 | 735
primary pancreatic ductal adenocarcinoma 9 | 1,109
spina bifida 9 | 1,074

Tissue

Digestive Tract 92 | 17,369
Endocrine System 92 | 18,159
Female tissues 91 | 17,400
Urinary Tract 91 | 16,678
Male tissues 90 | 17,142
Nervous System 90 | 16,725
Skin and soft tissues 90 | 17,230
Liver and Pancreas 89 | 16,750
Blood and immune system 88 | 16,909
Respiratory system 88 | 16,393
Cardiovascular System 82 | 15,192

Target Family

Non-IDG 43 | 12,091
Enzyme 21 | 4,145
Transcription Factor 9 | 1,400
GPCR 8 | 408
Epigenetic 4 | 242
Nuclear Receptor 4 | 48
Transporter 3 | 473
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

response to estradiol 94 | 94
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610