Development Level

Tbio 10 | 11,445

IMPC Phenotype

decreased circulating glucose ... 2 | 126
increased circulating triglyce... 2 | 42
abnormal behavior 1 | 298
abnormal duodenum morphology 1 | 4
abnormal eye morphology 1 | 68
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal nail morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased heart rate variabili... 1 | 13
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
hyperactivity 1 | 148
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased mean corpuscular hem... 1 | 36
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
short tibia 1 | 97

Disease

Carcinoma 7 | 11,493
glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
group 3 medulloblastoma 5 | 4,104
osteosarcoma 5 | 7,950
Obesity 4 | 678
Schizophrenia 4 | 1,160
astrocytic glioma 4 | 2,597
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
ovarian cancer 4 | 8,520
Alcoholic Intoxication, Chronic 3 | 289
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Atherosclerosis 3 | 291
Depressive disorder 3 | 409
Hyperglycemia 3 | 137
Nerve Degeneration 3 | 121
Pick disease 3 | 1,894
adult high grade glioma 3 | 3,801
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
nephrosclerosis 3 | 333
oligodendroglioma 3 | 2,850
pituitary cancer 3 | 1,972
Alzheimer Disease 2 | 83
Atopic dermatitis 2 | 952
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Cancer 2 | 2,499
Cerebrovascular disease 2 | 238
Coronary artery disease 2 | 268
Diabetes Mellitus, Experimental 2 | 108
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Fatty liver disease 2 | 103
Gastric ulcer 2 | 33
Heart disease 2 | 306
Hypercholesterolemia 2 | 44
Hypertension 2 | 396
Hypertensive disease 2 | 292
Hypertriglyceridemia result 2 | 37
Kidney disease 2 | 430
Lipid metabolism disorder 2 | 114
Liver disease 2 | 237
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Myocardial Infarction 2 | 151
Parkinson's disease 2 | 392
Proteinuria 2 | 144
Seizures 2 | 596
Stomach Ulcer 2 | 18
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
hearing impairment 2 | 199
interstitial cystitis 2 | 2,312
interstitial lung disease 2 | 298
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group B ependymoma 2 | 416
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
Abnormally small eyeball on both sides 1 | 5
Alcohol withdrawal syndrome 1 | 20
Bilateral nanophthalmos 1 | 5
Branchiooculofacial syndrome 1 | 13
Carotid stenosis 1 | 5
Decreased T cell activation 1 | 4
Decreased testosterone in males 1 | 28
Delirium 1 | 10
Dyslipidemias 1 | 27
Facial asymmetry 1 | 32
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Hyperphagia 1 | 23
Hyperthyroidism 1 | 53
Increased appetite (finding) 1 | 23
Lipodystrophy 1 | 40
Long tract signs 1 | 3
Macular Degeneration, Age-Related, 1 1 | 9
Metabolic Syndrome 1 | 20
Microphthalmia, bilateral 1 | 5
Polydipsia 1 | 15
Secondary hypothyroidism 1 | 15
Splenic infarction 1 | 6
Xerostomia 1 | 42

Tissue

Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Male tissues 8 | 17,142

Target Family

Non-IDG 8 | 12,091
Kinase 1 | 634
Transporter 1 | 473

GO Process

response to dietary excess 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ProSAAS PCSK1N Tbio Non-IDG -2.28833 188.0 73
Neurosecretory protein VGF VGF Tbio Non-IDG -2.12346 150.7 212
SH3-containing GRB2-like protein 3-interacting protein 1 SGIP1 Tbio Non-IDG -0.69901 5.35 72
Calcium-binding mitochondrial carrier protein SCaMC-2 SLC25A25 Tbio Transporter -1.43480 24.1 99
F-box-like/WD repeat-containing protein TBL1XR1 TBL1XR1 Tbio Non-IDG -1.93544 82.3 232
Activin receptor type-1C ACVR1C Tbio Kinase -1.53432 40.5 303
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha PPARGC1A Tbio Non-IDG -2.86449 728.1 274
Growth/differentiation factor 3 GDF3 Tbio Non-IDG -1.94534 87.4 332
Leptin LEP Tbio Non-IDG -4.17777 16050.7 1012