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Development Level

Tbio 30 | 11,445
Tchem 12 | 1,598
Tclin 8 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
abnormal behavior 2 | 298
abnormal humerus morphology 2 | 11
decreased body weight 2 | 161
decreased circulating iron lev... 2 | 32
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
enlarged lymph nodes 2 | 37
impaired righting response 2 | 26
increased bone mineral density 2 | 72
increased lymphocyte cell numb... 2 | 32
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal incisor color 1 | 3
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
absent vibrissae 1 | 12
cataract 1 | 92
decreased body length 1 | 101
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased neutrophil cell numb... 1 | 46
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small adrenal glands 1 | 16
small spleen 1 | 19
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Cancer 32 | 2,499
glioblastoma 31 | 5,792
osteosarcoma 29 | 7,950
ovarian cancer 29 | 8,520
psoriasis 29 | 6,694
Carcinoma 28 | 11,493
lung cancer 25 | 4,740
ependymoma 24 | 4,679
medulloblastoma, large-cell 22 | 6,241
Astrocytoma, Pilocytic 20 | 3,081
lung carcinoma 20 | 2,843
non-small cell lung cancer 20 | 2,890
atypical teratoid / rhabdoid tumor 18 | 5,112
Breast cancer 17 | 3,578
group 3 medulloblastoma 17 | 4,104
pituitary cancer 17 | 1,972
invasive ductal carcinoma 16 | 2,951
tuberculosis 16 | 2,010
Schizophrenia 15 | 1,160
adult high grade glioma 15 | 3,801
pancreatic cancer 15 | 2,398
ulcerative colitis 15 | 1,819
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
malignant mesothelioma 14 | 3,232
subependymal giant cell astrocytoma 14 | 2,287
colon cancer 13 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
oligodendroglioma 13 | 2,850
primitive neuroectodermal tumor 12 | 3,035
breast carcinoma 11 | 1,638
Multiple myeloma 10 | 1,332
diabetes mellitus 10 | 1,728
lung adenocarcinoma 10 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Arthritis 9 | 290
Asthma 9 | 385
Atopic dermatitis 9 | 952
Lung Neoplasms 9 | 232
Rheumatoid arthritis 9 | 1,191
ductal carcinoma in situ 9 | 1,745
gastric cancer 9 | 459
group 4 medulloblastoma 9 | 1,855
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Liver Cirrhosis, Experimental 8 | 769
Vascular disease 8 | 319
acute quadriplegic myopathy 8 | 1,158
juvenile dermatomyositis 8 | 1,187
Autosomal recessive predisposition 7 | 1,442
Carcinoma, Hepatocellular 7 | 228
Liver Cirrhosis 7 | 181
Liver carcinoma 7 | 240
Osteoporosis 7 | 363
Pick disease 7 | 1,894
active Crohn's disease 7 | 922
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
nasopharyngeal carcinoma 7 | 1,058
non primary Sjogren syndrome sicca 7 | 891
sarcoidosis 7 | 370
Hypertension 6 | 396
Kidney disease 6 | 430
Lung disease 6 | 142
Multiple Sclerosis 6 | 540
Prostatic Neoplasms 6 | 495
Short stature 6 | 531
adrenocortical carcinoma 6 | 1,428
cystic fibrosis 6 | 1,696
fibroadenoma 6 | 559
head and neck cancer 6 | 271
primary pancreatic ductal adenocarcinoma 6 | 1,109
Breast Neoplasms 5 | 445
COPD 5 | 118
Cholestasis, Extrahepatic 5 | 25
Cognitive delay 5 | 608
Colonic Neoplasms 5 | 142
Depressive disorder 5 | 409
Diabetes Mellitus, Experimental 5 | 108
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Global developmental delay 5 | 608
Heart disease 5 | 306
Hypertensive disease 5 | 292
Kidney cancer 5 | 2,613
Mammary Neoplasms 5 | 425
Mental and motor retardation 5 | 608
Polycystic ovary syndrome 5 | 360
active ulcerative colitis 5 | 764
acute myeloid leukemia 5 | 783
aldosterone-producing adenoma 5 | 665
gastric carcinoma 5 | 807
mucosa-associated lymphoid tissue lymphoma 5 | 484
pancreatic carcinoma 5 | 562
pediatric high grade glioma 5 | 1,064
periodontitis 5 | 293
primary Sjogren syndrome 5 | 735
progressive supranuclear palsy 5 | 676
pterygium 5 | 76
spina bifida 5 | 1,074
urothelial carcinoma 5 | 318

Tissue

Digestive Tract 51 | 17,369
Endocrine System 51 | 18,159
Liver and Pancreas 51 | 16,750
Blood and immune system 50 | 16,909
Female tissues 50 | 17,400
Male tissues 50 | 17,142
Respiratory system 50 | 16,393
Skin and soft tissues 50 | 17,230
Urinary Tract 50 | 16,678
Cardiovascular System 48 | 15,192
Nervous System 48 | 16,725

Target Family

Non-IDG 21 | 12,091
Enzyme 13 | 4,145
Transcription Factor 11 | 1,400
GPCR 2 | 408
Kinase 2 | 634
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GO Process

response to cytokine 51 | 51
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinal dehydrogenase 2 ALDH1A2 Tbio Enzyme -2.25078 175.3 229
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Geranylgeranyl transferase type-1 subunit beta PGGT1B Tchem Enzyme -1.51465 29.4 63
Leukemia inhibitory factor receptor LIFR Tbio Non-IDG -2.35146 221.3 249
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit DDOST Tchem Enzyme -1.60313 44.1 140
Transmembrane protein 102 TMEM102 Tbio Non-IDG -1.22014 17.5 71
Fos-related antigen 1 FOSL1 Tbio Transcription Factor -2.39870 235.8 243
Thymidylate synthase TYMS Tclin Enzyme -2.93426 732.0 733
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325