Development Level

Tbio 30 | 11,445
Tchem 12 | 1,598
Tclin 8 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
abnormal behavior 2 | 298
abnormal humerus morphology 2 | 11
decreased body weight 2 | 161
decreased circulating iron lev... 2 | 32
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
enlarged lymph nodes 2 | 37
impaired righting response 2 | 26
increased bone mineral density 2 | 72
increased lymphocyte cell numb... 2 | 32
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal incisor color 1 | 3
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
absent vibrissae 1 | 12
cataract 1 | 92
decreased body length 1 | 101
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased neutrophil cell numb... 1 | 46
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small adrenal glands 1 | 16
small spleen 1 | 19
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Cancer 32 | 2,499
glioblastoma 31 | 5,792
osteosarcoma 29 | 7,950
ovarian cancer 29 | 8,520
psoriasis 29 | 6,694
Carcinoma 28 | 11,493
lung cancer 25 | 4,740
ependymoma 24 | 4,679
medulloblastoma, large-cell 22 | 6,241
Astrocytoma, Pilocytic 20 | 3,081
lung carcinoma 20 | 2,843
non-small cell lung cancer 20 | 2,890
atypical teratoid / rhabdoid tumor 18 | 5,112
Breast cancer 17 | 3,578
group 3 medulloblastoma 17 | 4,104
pituitary cancer 17 | 1,972
invasive ductal carcinoma 16 | 2,951
tuberculosis 16 | 2,010
Schizophrenia 15 | 1,160
adult high grade glioma 15 | 3,801
pancreatic cancer 15 | 2,398
ulcerative colitis 15 | 1,819
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
malignant mesothelioma 14 | 3,232
subependymal giant cell astrocytoma 14 | 2,287
colon cancer 13 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
oligodendroglioma 13 | 2,850
primitive neuroectodermal tumor 12 | 3,035
breast carcinoma 11 | 1,638
Multiple myeloma 10 | 1,332
diabetes mellitus 10 | 1,728
lung adenocarcinoma 10 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Arthritis 9 | 290
Asthma 9 | 385
Atopic dermatitis 9 | 952
Lung Neoplasms 9 | 232
Rheumatoid arthritis 9 | 1,191
ductal carcinoma in situ 9 | 1,745
gastric cancer 9 | 459
group 4 medulloblastoma 9 | 1,855
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Liver Cirrhosis, Experimental 8 | 769
Vascular disease 8 | 319
acute quadriplegic myopathy 8 | 1,158
juvenile dermatomyositis 8 | 1,187
Autosomal recessive predisposition 7 | 1,442
Carcinoma, Hepatocellular 7 | 228
Liver Cirrhosis 7 | 181
Liver carcinoma 7 | 240
Osteoporosis 7 | 363
Pick disease 7 | 1,894
active Crohn's disease 7 | 922
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
nasopharyngeal carcinoma 7 | 1,058
non primary Sjogren syndrome sicca 7 | 891
sarcoidosis 7 | 370
Hypertension 6 | 396
Kidney disease 6 | 430
Lung disease 6 | 142
Multiple Sclerosis 6 | 540
Prostatic Neoplasms 6 | 495
Short stature 6 | 531
adrenocortical carcinoma 6 | 1,428
cystic fibrosis 6 | 1,696
fibroadenoma 6 | 559
head and neck cancer 6 | 271
primary pancreatic ductal adenocarcinoma 6 | 1,109
Breast Neoplasms 5 | 445
COPD 5 | 118
Cholestasis, Extrahepatic 5 | 25
Cognitive delay 5 | 608
Colonic Neoplasms 5 | 142
Depressive disorder 5 | 409
Diabetes Mellitus, Experimental 5 | 108
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Global developmental delay 5 | 608
Heart disease 5 | 306
Hypertensive disease 5 | 292
Kidney cancer 5 | 2,613
Mammary Neoplasms 5 | 425
Mental and motor retardation 5 | 608
Polycystic ovary syndrome 5 | 360
active ulcerative colitis 5 | 764
acute myeloid leukemia 5 | 783
aldosterone-producing adenoma 5 | 665
gastric carcinoma 5 | 807
mucosa-associated lymphoid tissue lymphoma 5 | 484
pancreatic carcinoma 5 | 562
pediatric high grade glioma 5 | 1,064
periodontitis 5 | 293
primary Sjogren syndrome 5 | 735
progressive supranuclear palsy 5 | 676
pterygium 5 | 76
spina bifida 5 | 1,074
urothelial carcinoma 5 | 318

Tissue

Digestive Tract 51 | 17,369
Endocrine System 51 | 18,159
Liver and Pancreas 51 | 16,750
Blood and immune system 50 | 16,909
Female tissues 50 | 17,400
Male tissues 50 | 17,142
Respiratory system 50 | 16,393
Skin and soft tissues 50 | 17,230
Urinary Tract 50 | 16,678
Cardiovascular System 48 | 15,192
Nervous System 48 | 16,725

Target Family

Non-IDG 21 | 12,091
Enzyme 13 | 4,145
Transcription Factor 11 | 1,400
GPCR 2 | 408
Kinase 2 | 634
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GO Process

response to cytokine 51 | 51
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Transmembrane protein 102 TMEM102 Tbio Non-IDG -1.22014 17.5 71
Leukemia inhibitory factor receptor LIFR Tbio Non-IDG -2.35146 221.3 249
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit DDOST Tchem Enzyme -1.60313 44.1 140
Thymidylate synthase TYMS Tclin Enzyme -2.93426 732.0 733
Geranylgeranyl transferase type-1 subunit beta PGGT1B Tchem Enzyme -1.51465 29.4 63
Retinal dehydrogenase 2 ALDH1A2 Tbio Enzyme -2.25078 175.3 229
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.36445 252.7 605
Calcium-dependent phospholipase A2 PLA2G5 Tchem Enzyme -1.38065 26.2 137