Development Level

Tbio 27 | 10,625
Tchem 14 | 1,890
Tclin 8 | 602

IMPC Term

decreased bone mineral content 4 | 157
preweaning lethality, complete... 3 | 633
abnormal humerus morphology 2 | 11
decreased lean body mass 2 | 195
enlarged lymph nodes 2 | 27
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal brain morphology 1 | 6
abnormal coat/hair pigmentatio... 1 | 54
abnormal coping response 1 | 12
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal incisor color 1 | 2
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal optic disc morphology 1 | 10
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
absent vibrissae 1 | 14
cataract 1 | 26
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 33
decreased circulating iron lev... 1 | 25
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased respiratory quotient 1 | 12
decreased startle reflex 1 | 48
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
impaired righting response 1 | 19
increased blood urea nitrogen ... 1 | 44
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 107
short tibia 1 | 82
shortened QT interval 1 | 4
small adrenal glands 1 | 15
small spleen 1 | 11
tremors 1 | 34

Disease

glioblastoma 30 | 5,572
Cancer 29 | 2,346
psoriasis 29 | 6,685
osteosarcoma 28 | 7,933
ovarian cancer 28 | 8,492
lung cancer 25 | 4,473
medulloblastoma, large-cell 22 | 6,234
pilocytic astrocytoma 21 | 3,086
lung carcinoma 20 | 2,844
non-small cell lung cancer 20 | 2,798
pituitary cancer 17 | 1,972
ulcerative colitis 17 | 2,087
invasive ductal carcinoma 16 | 2,950
atypical teratoid / rhabdoid tumor 15 | 4,369
pancreatic cancer 15 | 2,300
posterior fossa group A ependymoma 15 | 1,511
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
pediatric high grade glioma 14 | 2,712
subependymal giant cell astrocytoma 14 | 2,287
tuberculosis 14 | 1,563
Breast cancer 13 | 3,099
colon cancer 13 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,956
oligodendroglioma 13 | 2,849
malignant mesothelioma 12 | 3,163
primitive neuroectodermal tumor 12 | 3,031
astrocytoma 11 | 1,493
breast carcinoma 11 | 1,614
group 4 medulloblastoma 11 | 1,875
Multiple myeloma 10 | 1,328
diabetes mellitus 10 | 1,663
ependymoma 10 | 2,514
group 3 medulloblastoma 10 | 2,254
lung adenocarcinoma 10 | 2,714
Arthritis 9 | 248
Atopic dermatitis 9 | 944
ductal carcinoma in situ 9 | 1,745
interstitial cystitis 9 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
primary pancreatic ductal adenocarcinoma 9 | 1,271
Rheumatoid Arthritis 8 | 1,171
acute quadriplegic myopathy 8 | 1,157
gastric carcinoma 8 | 832
juvenile dermatomyositis 8 | 1,189
Liver Cirrhosis 7 | 101
Liver carcinoma 7 | 217
Pick disease 7 | 1,893
Vascular disease 7 | 281
active Crohn's disease 7 | 918
nasopharyngeal carcinoma 7 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
primary Sjogren syndrome 7 | 789
Asthma 6 | 349
IGA Glomerulonephritis 6 | 454
Kidney disease 6 | 397
Lung Neoplasms 6 | 171
Lung disease 6 | 136
Schizophrenia 6 | 503
adrenocortical carcinoma 6 | 1,427
adult high grade glioma 6 | 2,148
cystic fibrosis 6 | 1,670
fibroadenoma 6 | 557
gastric cancer 6 | 436
head and neck cancer 6 | 270
inflammatory breast cancer 6 | 404
medulloblastoma 6 | 1,524
sarcoidosis 6 | 368
COPD 5 | 116
Carcinoma 5 | 2,147
Diabetes Mellitus, Experimental 5 | 106
Down syndrome 5 | 548
Duchenne muscular dystrophy 5 | 602
Heart disease 5 | 279
Heat Stroke 5 | 12
Mammary Neoplasms 5 | 410
Multiple Sclerosis 5 | 498
Osteoporosis 5 | 259
Polycystic Ovary Syndrome 5 | 335
Prostatic Neoplasms 5 | 471
acute myeloid leukemia 5 | 785
aldosterone-producing adenoma 5 | 664
atypical teratoid/rhabdoid tumor 5 | 1,095
mucosa-associated lymphoid tissue lymphoma 5 | 480
non primary Sjogren syndrome sicca 5 | 840
pancreatic carcinoma 5 | 567
progressive supranuclear palsy 5 | 674
pterygium 5 | 74
sonic hedgehog group medulloblastoma 5 | 1,482
spina bifida 5 | 1,064
urothelial carcinoma 5 | 318
Becker muscular dystrophy 4 | 187
Waldenstrons macroglobulinemia 4 | 765
chronic lymphosyte leukemia 4 | 232
chronic rhinosinusitis 4 | 512
cutaneous lupus erythematosus 4 | 1,056
dermatomyositis 4 | 967
esophageal adenocarcinoma 4 | 737
nephrosclerosis 4 | 329
non diabetic and post-ischemic heart failure 4 | 200
periodontitis 4 | 269

Tissue

Blood and immune system 49 | 17,995
Digestive Tract 49 | 18,473
Endocrine System 49 | 18,512
Female tissues 49 | 18,647
Liver and Pancreas 49 | 18,136
Male tissues 49 | 17,969
Nervous System 49 | 18,561
Skin and soft tissues 49 | 18,115
Cardiovascular System 48 | 17,958
Respiratory system 48 | 17,484
Urinary Tract 48 | 18,444

Target Family

Non-IDG 20 | 11,969
Enzyme 12 | 4,146
Transcription Factor 11 | 1,400
GPCR 2 | 408
Kinase 2 | 634
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GO Process

response to cytokine 49 | 49
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leukemia inhibitory factor receptor LIFR Tchem Non-IDG -2.33661 212.2 213
Oncostatin-M-specific receptor subunit beta OSMR Tbio Non-IDG -2.24105 170.5 217
Metalloproteinase inhibitor 4 TIMP4 Tbio Enzyme -1.99351 100.3 348
Transmembrane protein 102 TMEM102 Tbio Non-IDG -1.22014 17.5 61
MAP kinase-activated protein kinase 2 MAPKAPK2 Tchem Kinase -2.14428 135.6 649
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.12726 13094.7 961
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.23151 1549.9 406
Interleukin-6 receptor subunit beta IL6ST Tclin Non-IDG -1.68650 50.5 476
Geranylgeranyl transferase type-1 subunit beta PGGT1B Tchem Enzyme -1.51052 29.4 60
Cbp/p300-interacting transactivator 1 CITED1 Tbio Non-IDG -1.71994 54.2 197