Development Level

Tbio 28 | 11,445
Tchem 12 | 1,598
Tclin 7 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal skin morphology 2 | 50
decreased body weight 2 | 161
decreased circulating alanine ... 2 | 47
decreased neutrophil cell numb... 2 | 42
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased mean corpuscular vol... 2 | 92
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal pericardium morpholog... 1 | 26
abnormal rib morphology 1 | 10
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
limb grasping 1 | 41
pale yolk sac 1 | 25
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 32 | 11,493
psoriasis 27 | 6,694
Cancer 26 | 2,499
ovarian cancer 24 | 8,520
glioblastoma 21 | 5,792
ependymoma 19 | 4,679
lung cancer 19 | 4,740
non-small cell lung cancer 19 | 2,890
Breast cancer 18 | 3,578
medulloblastoma, large-cell 18 | 6,241
atypical teratoid / rhabdoid tumor 16 | 5,112
lung adenocarcinoma 15 | 2,716
lung carcinoma 15 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
osteosarcoma 14 | 7,950
Autosomal recessive predisposition 13 | 1,442
diabetes mellitus 13 | 1,728
interstitial cystitis 13 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
adrenocortical carcinoma 12 | 1,428
group 4 medulloblastoma 12 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
invasive ductal carcinoma 12 | 2,951
adult high grade glioma 11 | 3,801
breast carcinoma 11 | 1,638
malignant mesothelioma 11 | 3,232
pituitary cancer 11 | 1,972
ulcerative colitis 11 | 1,819
Hypertension 10 | 396
Kidney cancer 10 | 2,613
Schizophrenia 10 | 1,160
astrocytoma 10 | 1,146
colon cancer 10 | 1,478
pancreatic cancer 10 | 2,398
Astrocytoma, Pilocytic 9 | 3,081
Obesity 9 | 678
oligodendroglioma 9 | 2,850
Hypertensive disease 8 | 292
Liver Cirrhosis, Experimental 8 | 769
Mental Depression 8 | 333
Rheumatoid arthritis 8 | 1,191
nasopharyngeal carcinoma 8 | 1,058
primitive neuroectodermal tumor 8 | 3,035
tuberculosis 8 | 2,010
urothelial carcinoma 8 | 318
Carcinoma, Hepatocellular 7 | 228
Kidney disease 7 | 430
Liver carcinoma 7 | 240
Multiple myeloma 7 | 1,332
Vascular disease 7 | 319
cystic fibrosis 7 | 1,696
ductal carcinoma in situ 7 | 1,745
gastric cancer 7 | 459
hepatocellular carcinoma 7 | 547
pterygium 7 | 76
Arthritis, Juvenile 6 | 126
Atherosclerosis 6 | 291
Breast Neoplasms 6 | 445
Depressive disorder 6 | 409
Juvenile arthritis 6 | 126
Lung Neoplasms 6 | 232
Mammary Neoplasms 6 | 425
Melanoma 6 | 711
Parkinson's disease 6 | 392
Short stature 6 | 531
active Crohn's disease 6 | 922
fibroadenoma 6 | 559
group 3 medulloblastoma 6 | 4,104
juvenile dermatomyositis 6 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Asthma 5 | 385
Liver Cirrhosis 5 | 181
Lung disease 5 | 142
Mood Disorders 5 | 184
Muscle hypotonia 5 | 571
Osteoporosis 5 | 363
Pick disease 5 | 1,894
Skin cancer 5 | 469
Status Epilepticus 5 | 98
acute myeloid leukemia 5 | 783
aldosterone-producing adenoma 5 | 665
astrocytic glioma 5 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
esophageal adenocarcinoma 5 | 737
gastric carcinoma 5 | 807
nephrosclerosis 5 | 333
pancreatic carcinoma 5 | 562
subependymal giant cell astrocytoma 5 | 2,287
Alzheimer's disease 4 | 658
Arthritis 4 | 290
Atopic dermatitis 4 | 952
Bipolar Disorder 4 | 666
Down syndrome 4 | 499
Endometriosis 4 | 540
Hypersensitivity reaction type II disease 4 | 253
Myocardial Ischemia 4 | 169
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
chronic lymphosyte leukemia 4 | 204
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Endocrine System 46 | 18,159
Female tissues 46 | 17,400
Digestive Tract 45 | 17,369
Skin and soft tissues 45 | 17,230
Liver and Pancreas 44 | 16,750
Urinary Tract 44 | 16,678
Blood and immune system 43 | 16,909
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Respiratory system 41 | 16,393
Cardiovascular System 39 | 15,192

Target Family

Enzyme 15 | 4,145
Non-IDG 12 | 12,091
Transcription Factor 10 | 1,400
Kinase 7 | 634
Epigenetic 1 | 242
Ion Channel 1 | 344
Transporter 1 | 473

GO Process

response to cAMP 47 | 47
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 Tclin Enzyme -2.97252 871.7 197
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -2.04034 130.8 476
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Sodium-dependent dopamine transporter SLC6A3 Tclin Transporter -3.59848 3752.4 324
Pyruvate kinase PKLR PKLR Tbio Kinase -2.37549 231.1 391
Tyrosinase TYR Tclin Enzyme -3.32888 2021.2 494
Calcium-dependent phospholipase A2 PLA2G5 Tchem Enzyme -1.38065 26.2 137
Diacylglycerol kinase theta DGKQ Tbio Kinase -1.58632 35.6 169
Fos-related antigen 1 FOSL1 Tbio Transcription Factor -2.39870 235.8 243