Development Level

Tbio 16 | 11,445
Tchem 12 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
decreased circulating glucose ... 1 | 126
increased cardiac muscle contr... 1 | 8
increased grip strength 1 | 41
increased heart left ventricle... 1 | 4
male infertility 1 | 123
small testis 1 | 58

Disease

Carcinoma 23 | 11,493
Cancer 22 | 2,499
ovarian cancer 22 | 8,520
lung cancer 19 | 4,740
osteosarcoma 16 | 7,950
psoriasis 16 | 6,694
glioblastoma 15 | 5,792
medulloblastoma, large-cell 12 | 6,241
atypical teratoid / rhabdoid tumor 11 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
ulcerative colitis 11 | 1,819
Rheumatoid arthritis 10 | 1,191
ependymoma 10 | 4,679
lung adenocarcinoma 10 | 2,716
lung carcinoma 10 | 2,843
non-small cell lung cancer 10 | 2,890
Hypertension 9 | 396
malignant mesothelioma 9 | 3,232
pancreatic cancer 9 | 2,398
Autosomal recessive predisposition 8 | 1,442
Brain Ischemia 8 | 110
Diabetes Mellitus, Experimental 8 | 108
Hypertensive disease 8 | 292
Schizophrenia 8 | 1,160
adult high grade glioma 8 | 3,801
diabetes mellitus 8 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
subependymal giant cell astrocytoma 8 | 2,287
tuberculosis 8 | 2,010
Astrocytoma, Pilocytic 7 | 3,081
Toxic encephalopathy 7 | 141
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
invasive ductal carcinoma 7 | 2,951
primary Sjogren syndrome 7 | 735
Anemia 6 | 365
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
Multiple myeloma 6 | 1,332
Obesity 6 | 678
Prostatic Neoplasms 6 | 495
Reperfusion Injury 6 | 86
Vascular disease 6 | 319
interstitial cystitis 6 | 2,312
pituitary cancer 6 | 1,972
Alzheimer's disease 5 | 658
Atherosclerosis 5 | 291
Bipolar Disorder 5 | 666
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Kidney cancer 5 | 2,613
Myocardial Infarction 5 | 151
Myocardial Ischemia 5 | 169
Neurodegenerative disease 5 | 414
Parkinson's disease 5 | 392
Thrombocytopenia 5 | 197
ductal carcinoma in situ 5 | 1,745
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
Amyotrophic lateral sclerosis 4 | 451
Arthritis 4 | 290
Asthma 4 | 385
Breast cancer 4 | 3,578
Calcinosis 4 | 70
Carcinoma, Hepatocellular 4 | 228
Cell Transformation, Neoplastic 4 | 97
Contact Dermatitis 4 | 81
Dermatitis, Contact 4 | 71
Diabetes Mellitus, Type 2 4 | 142
Diabetic retinopathy 4 | 56
Edema 4 | 81
Endometriosis 4 | 540
Immune system cancer 4 | 140
Infertility, Male 4 | 46
Inflammation 4 | 120
Kidney disease 4 | 430
Liver carcinoma 4 | 240
Liver disease 4 | 237
Major Depressive Disorder 4 | 301
Melanoma 4 | 711
Myocardial Reperfusion Injury 4 | 37
Neoplastic Cell Transformation 4 | 89
Pancreatitis 4 | 123
Pulmonary Fibrosis 4 | 106
Seizures 4 | 596
Short stature 4 | 531
Skin Neoplasms 4 | 69
Somatic mutation 4 | 61
Splenomegaly 4 | 190
Squamous cell carcinoma 4 | 129
Unipolar Depression 4 | 250
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
gastric cancer 4 | 459
group 3 medulloblastoma 4 | 4,104
group 4 medulloblastoma 4 | 1,855
hepatocellular carcinoma 4 | 547
juvenile dermatomyositis 4 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Down syndrome 3 | 499

Tissue

Blood and immune system 34 | 16,909
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Nervous System 34 | 16,725
Respiratory system 34 | 16,393
Skin and soft tissues 34 | 17,230
Urinary Tract 34 | 16,678
Cardiovascular System 32 | 15,192

Target Family

Enzyme 16 | 4,145
Non-IDG 10 | 12,091
Transcription Factor 3 | 1,400
GPCR 2 | 408
Kinase 2 | 634
Transporter 1 | 473

GO Process

response to antibiotic 34 | 34
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Beta-3 adrenergic receptor ADRB3 Tclin GPCR -2.73090 568.4 254
MHC class II transactivator CIITA Tbio Non-IDG -2.63957 506.8 146
Cytochrome b-c1 complex subunit Rieske, mitochondrial UQCRFS1 Tbio Non-IDG -2.12377 231.9 211
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Endonuclease G, mitochondrial ENDOG Tbio Enzyme -2.22791 175.9 334
Cytochrome b5 reductase 4 CYB5R4 Tbio Enzyme -1.15554 17.5 107
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Protein C-ets-1 ETS1 Tbio Transcription Factor -2.89500 760.0 463
Amiloride-sensitive amine oxidase [copper-containing] AOC1 Tchem Enzyme -2.77629 590.0 271