Development Level

Tbio 26 | 11,445
Tchem 11 | 1,598
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hyperactivity 1 | 148
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased heart left ventricle... 1 | 4
increased lean body mass 1 | 172
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 25 | 11,493
Cancer 24 | 2,499
ovarian cancer 22 | 8,520
psoriasis 20 | 6,694
osteosarcoma 18 | 7,950
glioblastoma 17 | 5,792
Autosomal recessive predisposition 16 | 1,442
medulloblastoma, large-cell 16 | 6,241
Obesity 15 | 678
diabetes mellitus 15 | 1,728
invasive ductal carcinoma 14 | 2,951
lung cancer 14 | 4,740
ependymoma 13 | 4,679
Schizophrenia 12 | 1,160
lung adenocarcinoma 12 | 2,716
Hyperglycemia 11 | 137
Hypertension 11 | 396
group 3 medulloblastoma 11 | 4,104
non-small cell lung cancer 11 | 2,890
Hypertensive disease 10 | 292
Major Depressive Disorder 10 | 301
atypical teratoid / rhabdoid tumor 10 | 5,112
breast carcinoma 10 | 1,638
interstitial cystitis 10 | 2,312
malignant mesothelioma 10 | 3,232
Liver Cirrhosis, Experimental 9 | 769
Unipolar Depression 9 | 250
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
ulcerative colitis 9 | 1,819
Breast cancer 8 | 3,578
Kidney disease 8 | 430
Prostatic Neoplasms 8 | 495
adrenocortical carcinoma 8 | 1,428
ductal carcinoma in situ 8 | 1,745
lung carcinoma 8 | 2,843
nasopharyngeal carcinoma 8 | 1,058
tuberculosis 8 | 2,010
Asthma 7 | 385
Astrocytoma, Pilocytic 7 | 3,081
Atherosclerosis 7 | 291
Depressive disorder 7 | 409
Kidney cancer 7 | 2,613
Mental Depression 7 | 333
Toxic encephalopathy 7 | 141
adult high grade glioma 7 | 3,801
colon cancer 7 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
primitive neuroectodermal tumor 7 | 3,035
Alcoholic Intoxication, Chronic 6 | 289
Alzheimer's disease 6 | 658
Atopic dermatitis 6 | 952
Autistic Disorder 6 | 364
Bipolar Disorder 6 | 666
Diabetes Mellitus, Experimental 6 | 108
Diabetes Mellitus, Non-Insulin-Dependent 6 | 145
Diabetes Mellitus, Type 2 6 | 142
Inflammation 6 | 120
Intellectual disability 6 | 1,016
Liver disease 6 | 237
Mood Disorders 6 | 184
Multiple myeloma 6 | 1,332
Seizures 6 | 596
acute quadriplegic myopathy 6 | 1,158
oligodendroglioma 6 | 2,850
Anemia 5 | 365
Arthritis 5 | 290
Cerebrovascular disease 5 | 238
Chemical and Drug Induced Liver Injury 5 | 195
Cognitive delay 5 | 608
Coronary artery disease 5 | 268
Endometriosis 5 | 540
Fatty Liver 5 | 70
Fatty liver disease 5 | 103
Global developmental delay 5 | 608
Heart disease 5 | 306
Hypoglycemia 5 | 152
Lipid metabolism disorder 5 | 114
Melanoma 5 | 711
Mental and motor retardation 5 | 608
Myocardial Infarction 5 | 151
Myocardial Reperfusion Injury 5 | 37
Osteoporosis 5 | 363
Reperfusion Injury 5 | 86
Rheumatoid arthritis 5 | 1,191
aldosterone-producing adenoma 5 | 665
astrocytoma 5 | 1,146
cutaneous lupus erythematosus 5 | 1,057
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
juvenile dermatomyositis 5 | 1,187
pancreatic cancer 5 | 2,398
Anorexia nervosa 4 | 80
Arthritis, Rheumatoid 4 | 174
Myocardial Ischemia 4 | 169
Waldenstrons macroglobulinemia 4 | 765
astrocytic glioma 4 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
fibroadenoma 4 | 559
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
periodontitis 4 | 293
pituitary cancer 4 | 1,972

Tissue

Endocrine System 40 | 18,159
Nervous System 38 | 16,725
Skin and soft tissues 38 | 17,230
Blood and immune system 37 | 16,909
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Digestive Tract 36 | 17,369
Female tissues 36 | 17,400
Urinary Tract 36 | 16,678
Respiratory system 34 | 16,393
Cardiovascular System 33 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 11 | 4,145
Kinase 5 | 634
Epigenetic 3 | 242
Transcription Factor 2 | 1,400
GPCR 1 | 408
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

response to activity 40 | 40
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Cytochrome b-c1 complex subunit 1, mitochondrial UQCRC1 Tbio Enzyme -1.46124 30.0 217
Mitochondrial uncoupling protein 3 UCP3 Tbio Non-IDG -2.74050 585.4 181
Lysine-specific demethylase 6B KDM6B Tchem Epigenetic -2.22888 174.2 272
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.84388 738.4 199
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH Tbio Enzyme -2.48697 296.4 389