Development Level

Tbio 4 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

increased circulating sodium l... 1 | 71
preweaning lethality, incomple... 1 | 499

Disease

Cancer 4 | 2,499
Carcinoma 4 | 11,493
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Breast cancer 3 | 3,578
Kidney cancer 3 | 2,613
Short stature 3 | 531
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
Adenocarcinoma of lung 2 | 142
Adenocarcinoma of lung (disorder) 2 | 60
Aplasia/Hypoplasia of the skin 2 | 16
Autosomal recessive predisposition 2 | 1,442
Blepharophimosis 2 | 70
Broad flat nasal bridge 2 | 236
Cataract 2 | 297
Cockayne syndrome 2 | 60
Colorectal Neoplasms 2 | 243
Hyperkeratosis 2 | 50
Hypogonadism 2 | 173
Hypoplastic mandible condyle 2 | 275
Lens Opacities 2 | 231
Lung Neoplasms 2 | 232
Mandibular hypoplasia 2 | 275
Melanoma 2 | 711
Meningioma 2 | 41
Micrognathism 2 | 275
Nasal bridge wide 2 | 236
Neoplasm Metastasis 2 | 168
Neoplasms, Squamous Cell 2 | 3
Nijmegen breakage syndrome 2 | 24
Pancreatic Neoplasm 2 | 85
Photosensitive trichothiodystrophy 2 | 30
Photosensitivity of skin 2 | 51
Prostate cancer 2 | 175
Skin Ulcer 2 | 48
Sparse scalp hair 2 | 42
Squamous Cell Neoplasms 2 | 3
Stomach Neoplasms 2 | 300
Vertical Talus 2 | 25
XFE progeroid syndrome 2 | 3
Xeroderma pigmentosum 2 | 43
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
psoriasis 2 | 6,694
Abnormal hair whorls 1 | 5
Abnormal lactate dehydrogenase activity 1 | 2
Abnormality of the clitoris 1 | 3
Abnormality of the nasopharynx 1 | 9
Abnormality of the thorax 1 | 19
Absence of Stensen duct 1 | 4
Absent scalp hair 1 | 5
Agenesis of parotid duct 1 | 4
Agenesis of punctum lacrimale 1 | 4
Aplasia/Hypoplasia involving the metacarpal bones 1 | 5
Breast Neoplasms, Male 1 | 4
CAMFAK syndrome 1 | 4
COFS syndrome 1 | 5
Cerebrooculofacioskeletal Syndrome 1 1 | 4
Congenital Foot Deformity 1 | 4
Congenital Hand Deformities 1 | 8
Congenital neurologic anomalies 1 | 20
Duplicated collecting system 1 | 7
Dystrophic toenail changes 1 | 12
Fingernail dysplasia 1 | 6
Fingerprints, Absence of 1 | 4
Foot Deformities, Congenital 1 | 4
Gastrointestinal system cancer 1 | 3
Genetic Predisposition to Disease 1 | 27
Hand Deformities, Congenital 1 | 8
Hyperconvex fingernails 1 | 7
Lacrimal Puncta, Absence of 1 | 4
Lacrimation abnormality 1 | 4
Lipoatrophy 1 | 19
Loss of scalp hair 1 | 5
Malignant neoplasm of breast 1 | 15
Oligodactyly 1 | 6
Oval face 1 | 5
Patchy alopecia 1 | 5
Pena Shokeir syndrome Type 2 1 | 4
Pili Torti 1 | 6
Pili canaliculi 1 | 4
Premature arteriosclerosis 1 | 5
Premature hardening of arteries 1 | 5
Progeria 1 | 25
Prostate cancer, familial 1 | 13
Split hand-foot malformation 1 | 18
Subcutaneous calcification 1 | 2
Thyroid Hormone Metabolism, Abnormal 1 | 2
Toe contractures 1 | 5
Urethral atresia 1 | 4
Velopharyngeal Insufficiency 1 | 8
Velopharyngeal dysfunction 1 | 8
Warsaw breakage syndrome 1 | 11
White forelock 1 | 12
Wizened face 1 | 9

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 2 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

replicative cell aging 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor protein 63 TP63 Tbio Transcription Factor -3.07398 1154.1 448
DNA excision repair protein ERCC-1 ERCC1 Tbio Non-IDG -3.02686 1089.9 878
Serine/threonine-protein kinase Chk2 CHEK2 Tchem Kinase -3.00304 978.7 1374
Werner syndrome ATP-dependent helicase WRN Tbio Enzyme -2.73759 569.7 210
Reactive oxygen species modulator 1 ROMO1 Tbio Non-IDG -1.59157 39.5 80