Development Level

Tbio 23 | 11,445
Tchem 7 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

increased circulating total pr... 3 | 28
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
decreased circulating chloride... 1 | 30
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased large unstained cell... 1 | 11
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 29 | 11,493
ovarian cancer 19 | 8,520
osteosarcoma 15 | 7,950
atypical teratoid / rhabdoid tumor 14 | 5,112
psoriasis 14 | 6,694
medulloblastoma, large-cell 13 | 6,241
glioblastoma 12 | 5,792
adult high grade glioma 11 | 3,801
ependymoma 11 | 4,679
lung cancer 11 | 4,740
non-small cell lung cancer 10 | 2,890
primitive neuroectodermal tumor 10 | 3,035
Kidney disease 9 | 430
astrocytic glioma 9 | 2,597
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
Kidney cancer 8 | 2,613
group 3 medulloblastoma 8 | 4,104
pancreatic cancer 8 | 2,398
Breast cancer 7 | 3,578
Carney complex 7 | 25
Depressive disorder 7 | 409
Hypertension 7 | 396
diabetes mellitus 7 | 1,728
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung carcinoma 7 | 2,843
Cancer 6 | 2,499
Hypertensive disease 6 | 292
lung adenocarcinoma 6 | 2,716
oligodendroglioma 6 | 2,850
ulcerative colitis 6 | 1,819
Acquired metabolic disease 5 | 336
Bipolar Disorder 5 | 666
Cardiomyopathies 5 | 110
Cushing's syndrome 5 | 48
Epilepsy 5 | 792
Mental Depression 5 | 333
Mood Disorders 5 | 184
Obesity 5 | 678
Primary pigmented nodular adrenocortical disease 5 | 13
gastric carcinoma 5 | 807
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
pituitary cancer 5 | 1,972
Congestive heart failure 4 | 113
Diabetes insipidus 4 | 18
Dull intelligence 4 | 645
Feeding difficulties in infancy 4 | 175
Growth delay 4 | 114
Growth failure 4 | 114
Growth retardation 4 | 115
Heart failure 4 | 162
Inappropriate ADH syndrome 4 | 5
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Meniere's disease 4 | 24
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Neurohypophyseal diabetes insipidus 4 | 13
Polydipsia 4 | 15
Poor growth 4 | 114
Poor school performance 4 | 645
Schizophrenia 4 | 1,160
Short stature 4 | 531
Substance Withdrawal Syndrome 4 | 55
Very poor growth 4 | 114
Vomiting 4 | 116
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
cutaneous lupus erythematosus 4 | 1,057
ductal carcinoma in situ 4 | 1,745
medulloblastoma 4 | 720
subependymal giant cell astrocytoma 4 | 2,287
Adenoma 3 | 167
Cerebrovascular disease 3 | 238
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Failure to gain weight 3 | 365
Hypothyroidism 3 | 122
Major Depressive Disorder 3 | 301
Melanoma 3 | 711
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Pituitary adenoma 3 | 38
Psychotic Disorders 3 | 151
Seizures 3 | 596
Unipolar Depression 3 | 250
Waldenstrons macroglobulinemia 3 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
dermatomyositis 3 | 966
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 32 | 18,159
Male tissues 30 | 17,142
Urinary Tract 30 | 16,678
Digestive Tract 29 | 17,369
Skin and soft tissues 29 | 17,230
Blood and immune system 28 | 16,909
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Nervous System 28 | 16,725
Cardiovascular System 27 | 15,192
Respiratory system 27 | 16,393

Target Family

Enzyme 16 | 4,145
Non-IDG 12 | 12,091
Kinase 3 | 634
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Process

renal water homeostasis 33 | 33
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Adenylate cyclase type 6 ADCY6 Tchem Enzyme -2.05332 113.7 111
Cytochrome P450 4A11 CYP4A11 Tbio Non-IDG -1.97180 93.7 142
Wolframin WFS1 Tbio Non-IDG -2.40006 260.2 118
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.61657 45.3 134
Cytochrome P450 11B2, mitochondrial CYP11B2 Tchem Non-IDG -2.82678 695.9 162
Aquaporin-4 AQP4 Tbio Non-IDG -3.33435 2159.1 358
Aquaporin-3 AQP3 Tbio Non-IDG -2.61717 403.0 260