Development Level

Tbio 17 | 11,445
Tchem 4 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to t... 5 | 278
abnormal embryo size 4 | 220
embryonic lethality prior to o... 4 | 239
embryonic growth retardation 3 | 106
abnormal heart morphology 2 | 162
abnormal placenta size 2 | 20
anophthalmia 2 | 33
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain morphology 1 | 10
abnormal head shape 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta morphology 1 | 5
abnormal skin coloration 1 | 25
brachydactyly 1 | 19
decreased circulating alanine ... 1 | 47
decreased circulating glucose ... 1 | 126
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
edema 1 | 59
enlarged heart 1 | 210
increased circulating alanine ... 1 | 13
increased circulating glucose ... 1 | 24
increased hematocrit 1 | 46
increased mean corpuscular vol... 1 | 92
microphthalmia 1 | 26
pallor 1 | 34
prenatal lethality 1 | 28
syndactyly 1 | 23
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 14 | 8,520
Carcinoma 12 | 11,493
glioblastoma 11 | 5,792
osteosarcoma 11 | 7,950
psoriasis 11 | 6,694
medulloblastoma, large-cell 10 | 6,241
atypical teratoid / rhabdoid tumor 9 | 5,112
adrenocortical carcinoma 8 | 1,428
lung cancer 8 | 4,740
Breast cancer 7 | 3,578
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
Cancer 6 | 2,499
adult high grade glioma 6 | 3,801
colon cancer 6 | 1,478
ependymoma 6 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung adenocarcinoma 6 | 2,716
primitive neuroectodermal tumor 6 | 3,035
Atopic dermatitis 5 | 952
Endometriosis 5 | 540
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
esophageal adenocarcinoma 3 | 737
nasopharyngeal carcinoma 3 | 1,058
non primary Sjogren syndrome sicca 3 | 891
primary Sjogren syndrome 3 | 735
ulcerative colitis 3 | 1,819
Astrocytoma, Pilocytic 2 | 3,081
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
medulloblastoma 2 | 720
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group A ependymoma 2 | 468
Acquired metabolic disease 1 | 336
Alcoholic Intoxication, Chronic 1 | 289
Alopecia areata 1 | 41
Amyotrophic lateral sclerosis 1 | 451
Arsenic Poisoning 1 | 62
Arthritis, Juvenile 1 | 126
Asthma 1 | 385
Breast Neoplasms 1 | 445
Cardiac arrest 1 | 36
Chronic obstructive pulmonary disease 1 | 184
DOID:9917 1 | 31
Dermatologic disorders 1 | 93
Diffuse large B-cell lymphoma 1 | 39
Duchenne muscular dystrophy 1 | 601
Exophthalmos 1 | 112
Gaucher disease type 1 1 | 180
Glioma 1 | 74
Juvenile arthritis 1 | 126
Leukemia 1 | 104
Liver Cirrhosis, Experimental 1 | 769
Lymphoma, Large B-Cell, Diffuse 1 | 34
Mammary Neoplasms 1 | 425
Melanoma 1 | 711
Multiple myeloma 1 | 1,332
Neuronal ceroid lipofuscinosis 1 | 28
Neuronal ceroid lipofuscinosis 2 1 | 17
Neutropenia 1 | 72
Osteoporosis 1 | 363
Polycystic ovary syndrome 1 | 360
Polyploidy 1 | 4
Reactive arthritis 1 | 7
Skin Diseases 1 | 71
Spinocerebellar ataxia type 1 1 | 16
Syringomyelia 1 | 15
Toxoplasmosis 1 | 17
Type 2 diabetes mellitus 1 | 272
Varicocele 1 | 26
aldosterone-producing adenoma 1 | 665
cutaneous lupus erythematosus 1 | 1,057
dermatomyositis 1 | 966
interstitial lung disease 1 | 298
juvenile dermatomyositis 1 | 1,187
limb girdle muscular dystrophy 2B 1 | 40
lung carcinoma 1 | 2,843
mucosa-associated lymphoid tissue lymphoma 1 | 484
non diabetic and post-ischemic heart failure 1 | 200
non-small cell lung carcinoma 1 | 317
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
sarcoidosis 1 | 370
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis 1 | 2,010

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678

Target Family

Enzyme 10 | 4,145
Non-IDG 10 | 12,091
Kinase 3 | 634

GO Process

regulation of ubiquitin-protei... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anaphase-promoting complex subunit 10 ANAPC10 Tbio Enzyme -1.23751 18.1 156
Anaphase-promoting complex subunit 11 ANAPC11 Tbio Enzyme -1.27406 17.9 239
Anaphase-promoting complex subunit 2 ANAPC2 Tbio Enzyme -0.45557 2.44 166
Anaphase-promoting complex subunit 4 ANAPC4 Tbio Enzyme 0.43 0.13 156
Anaphase-promoting complex subunit 7 ANAPC7 Tbio Enzyme -0.17118 1.40 73
Cell division cycle protein 23 homolog CDC23 Tbio Non-IDG -1.50528 30.4 191
Anaphase-promoting complex subunit 15 ANAPC15 Tdark Enzyme -0.41378 2.22 27
Ubiquitin-conjugating enzyme E2 C UBE2C Tbio Non-IDG -1.93680 92.1 352
Anaphase-promoting complex subunit 1 ANAPC1 Tbio Enzyme -1.60064 37.3 408
Cell division cycle protein 20 homolog CDC20 Tbio Non-IDG -2.60409 401.5 393