Development Level

Tchem 2 | 1,598

Disease

Carcinoma 2 | 11,493
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
Abnormal development of end part of bone 1 | 14
Abnormality of the metaphyses 1 | 48
Amino Acid Metabolism, Inborn Errors 1 | 13
Barrel chest 1 | 12
Brachydactyly 1 | 156
Carpal bone hypoplasia 1 | 6
Central nervous system disease 1 | 10
Chronic Liver Failure 1 | 2
Concave bridge of nose 1 | 195
Cone-shaped epiphyses of phalanges 1 | 15
Congenital Heart Defects 1 | 58
Congenital heart disease 1 | 93
Coxa valga 1 | 22
Coxa valga deformity 1 | 22
Death in early childhood 1 | 82
Death in infancy 1 | 82
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Dehydration 1 | 40
Diabetes Mellitus, Insulin-Dependent 1 | 48
Disproportionately short middle phalanges 1 | 6
Elevated hepatic transaminases 1 | 81
Enlarged thorax 1 | 18
Epiphyseal dysplasia 1 | 14
Familial primary pulmonary hypertension 1 | 11
Flat epiphyses 1 | 7
Generalized osteopenia 1 | 99
Globe disease 1 | 67
Glycosuria 1 | 29
Hair Diseases 1 | 3
Hepatic enzyme increased 1 | 81
High forehead 1 | 102
Hyperglycemia 1 | 137
Hyperopia 1 | 70
Hypertension, Pulmonary 1 | 37
Hyperuricemia 1 | 49
Immune System Diseases 1 | 4
Infantile onset 1 | 238
Insulin resistant diabetes 1 | 13
Intracerebral periventricular calcifications 1 | 2
Irregular ankle bone maturation 1 | 1
Irregular carpal bones 1 | 2
Irregular tarsal ossification 1 | 1
Irregular vertebral endplates 1 | 16
Ivory epiphyses of the toes 1 | 1
Ketoacidosis 1 | 11
Kidney Failure 1 | 111
Knee joint valgus deformity 1 | 56
Liver Dysfunction 1 | 99
Liver Failure, Acute 1 | 29
Liver cancer 1 | 604
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Lordosis 1 | 54
Microdontia (disorder) 1 | 59
Motor delay 1 | 147
Multiple epiphyseal dysplasia 1 | 18
Muscle Hypertonia 1 | 88
Muscular Diseases 1 | 27
Myopathy 1 | 185
Narrow iliac wings 1 | 7
Neutrophil count decreased 1 | 47
No development of motor milestones 1 | 147
ODONTOID HYPOPLASIA 1 | 16
Osteopenia 1 | 99
Osteoporosis 1 | 363
Platyspondyly 1 | 56
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Primary pulmonary hypertension 1 | 14
Pulmonary Veno-Occlusive Disease (disorder) 1 | 2
Pulmonary Venoocclusive Disease 1, Autosomal Dominant 1 | 2
Pulmonary capillary hemangiomatosis 1 | 2
Pulmonary hypertension 1 | 85
Pulmonary venoocclusive disease 1 | 3
Reduced pancreatic beta cells 1 | 6
Renal Insufficiency 1 | 90
Renal failure in adulthood 1 | 76
Renal tubular disorder 1 | 12
Sclerotic ivory phalangeal epiphyses 1 | 3
Short thorax 1 | 21
Small epiphyses 1 | 9
Small wrist bones 1 | 6
Status Epilepticus 1 | 98
Steatorrhea 1 | 34
Subclinical abnormal liver function tests 1 | 81
Supranuclear Palsy, Progressive 1 | 6
Tall forehead 1 | 102
Transaminases increased 1 | 81
Transient neonatal diabetes mellitus 1 | 14
Triangular face 1 | 58
Weight decreased 1 | 103
Wolcott-Rallison dysplasia 1 | 1
Wolcott-Rallison syndrome 1 | 10
ileal Crohn's disease 1 | 9

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Kinase 2 | 634

GO Process

regulation of translational in... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eukaryotic translation initiation factor 2-alpha kinase 3 EIF2AK3 Tchem Kinase -3.05781 896.8 450
eIF-2-alpha kinase GCN2 EIF2AK4 Tchem Kinase -2.43702 276.5 301