Development Level

Tbio 29 | 10,625
Tchem 9 | 1,890
Tdark 9 | 7,003
Tclin 1 | 602

Collection

Kinase: IDG Consortium (Complete/Control) 1 | 37
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 3 | 260
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 37
decreased circulating choleste... 2 | 85
decreased grip strength 2 | 123
increased mean corpuscular vol... 2 | 91
increased startle reflex 2 | 38
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal coat-hair pigmentatio... 1 | 54
abnormal coping response 1 | 12
abnormal gait 1 | 51
abnormal glucose homeostasis 1 | 5
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal sleep behavior 1 | 63
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased lactate dehydrogenas... 1 | 14
decreased lean body mass 1 | 195
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased effector memory CD8-... 1 | 14
increased mean corpuscular hem... 1 | 93
premature death 1 | 5
prolonged QRS complex duration 1 | 2
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

ovarian cancer 30 | 8,491
osteosarcoma 24 | 7,933
medulloblastoma, large-cell 18 | 6,234
glioblastoma 17 | 5,572
psoriasis 16 | 6,685
lung cancer 13 | 4,473
Cancer 12 | 2,346
atypical teratoid / rhabdoid tumor 12 | 4,369
group 3 medulloblastoma 12 | 2,254
Breast cancer 10 | 3,098
primitive neuroectodermal tumor 10 | 3,031
subependymal giant cell astrocytoma 10 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
acute quadriplegic myopathy 8 | 1,157
ependymoma 8 | 2,514
pilocytic astrocytoma 8 | 3,086
Multiple myeloma 7 | 1,327
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
malignant mesothelioma 7 | 3,163
pediatric high grade glioma 7 | 2,712
Carcinoma 6 | 2,147
Pick disease 6 | 1,893
astrocytoma 6 | 1,493
dermatomyositis 6 | 966
diabetes mellitus 6 | 1,663
lung carcinoma 6 | 2,844
non-small cell lung cancer 6 | 2,798
oligodendroglioma 6 | 2,849
Mammary Neoplasms 5 | 410
Parkinson's disease 5 | 364
Waldenstrons macroglobulinemia 5 | 764
adult high grade glioma 5 | 2,148
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
breast carcinoma 5 | 1,614
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
invasive ductal carcinoma 5 | 2,950
Amyotrophic Lateral Sclerosis 4 | 432
Infertility 4 | 163
Obesity 4 | 616
astrocytic glioma 4 | 2,241
colon cancer 4 | 1,475
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,299
pancreatic cancer 4 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pituitary cancer 4 | 1,972
sonic hedgehog group medulloblastoma 4 | 1,482
tuberculosis 4 | 1,563
Alzheimer's disease 3 | 644
Asthma 3 | 349
Brain Diseases 3 | 22
Brain disease 3 | 84
Male infertility 3 | 170
Rheumatoid Arthritis 3 | 1,170
Squamous cell carcinoma 3 | 96
Stomach Neoplasms 3 | 282
adrenocortical carcinoma 3 | 1,427
atypical teratoid/rhabdoid tumor 3 | 1,095
chronic lymphosyte leukemia 3 | 232
cystic fibrosis and chronic rhinosinusitis 3 | 213
fibroadenoma 3 | 557
group 4 medulloblastoma 3 | 1,875
juvenile dermatomyositis 3 | 1,189
lung adenocarcinoma 3 | 2,714
medulloblastoma 3 | 1,524
nasopharyngeal carcinoma 3 | 1,056
non primary Sjogren syndrome sicca 3 | 840
posterior fossa group A ependymoma 3 | 1,511
posterior fossa group B ependymoma 3 | 1,530
tuberculosis and treatment for 6 months 3 | 686
ulcerative colitis 3 | 2,087
Anemia 2 | 252
Arthritis 2 | 248
Atopic dermatitis 2 | 944
Attention deficit hyperactivity disorder 2 | 156
Chronic obstructive pulmonary disease 2 | 147
Colonic Neoplasms 2 | 126
Colorectal Neoplasms 2 | 217
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Epilepsy 2 | 346
Heart disease 2 | 279
Hydrolethalus syndrome 2 | 128
Kidney disease 2 | 397
Liver carcinoma 2 | 217
Lung Neoplasms 2 | 171
Neurodegenerative disease 2 | 383
Peripheral Neuropathy 2 | 303
Polycystic Ovary Syndrome 2 | 334
Primary biliary cirrhosis 2 | 45
Prostatic Neoplasms 2 | 471
Schizophrenia 2 | 503
Substance-Related Disorders 2 | 114
Toxic encephalopathy 2 | 131
Type 2 diabetes mellitus 2 | 192
Vascular disease 2 | 281
chronic rhinosinusitis 2 | 512
primary pancreatic ductal adenocarcinoma 2 | 1,271
progressive supranuclear palsy 2 | 674
spina bifida 2 | 1,064

Tissue

Blood and immune system 48 | 17,994
Digestive Tract 48 | 18,472
Endocrine System 48 | 18,511
Female tissues 48 | 18,646
Liver and Pancreas 48 | 18,135
Male tissues 48 | 17,968
Nervous System 48 | 18,560
Urinary Tract 48 | 18,443
Cardiovascular System 47 | 17,957
Respiratory system 47 | 17,483
Skin and soft tissues 47 | 18,114

Target Family

Non-IDG 34 | 11,969
Enzyme 7 | 4,146
Kinase 5 | 634
Transcription Factor 2 | 1,400

GO Process

regulation of translation 48 | 48
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable ATP-dependent RNA helicase DDX6 DDX6 Tbio Enzyme -1.77534 57.8 244
Eukaryotic translation initiation factor 2A EIF2A Tbio Non-IDG -0.57210 3.87 227
60S ribosomal protein L38 RPL38 Tdark Non-IDG -1.39373 24.2 45
Protein LSM14 homolog B LSM14B Tdark Non-IDG -0.55731 2.94 35
Thymidylate synthase TYMS Tclin Enzyme -2.92025 722.7 471
Eukaryotic translation initiation factor 4E type 3 EIF4E3 Tbio Non-IDG -0.94340 7.46 56
DnaJ homolog subfamily C member 1 DNAJC1 Tbio Transcription Factor -0.90043 8.37 56
Hamartin TSC1 Tbio Non-IDG -2.23602 165.3 1376
Piwi-like protein 4 PIWIL4 Tbio Non-IDG -2.70514 481.4 145
Piwi-like protein 3 PIWIL3 Tdark Non-IDG -0.65250 3.54 56