Development Level

Tbio 37 | 11,445
Tchem 9 | 1,598
Tdark 7 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal sleep behavior 2 | 70
decreased circulating LDL chol... 2 | 38
decreased circulating choleste... 2 | 93
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
thrombocytopenia 2 | 56
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased lactate dehydrogenas... 1 | 16
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
hydrometra 1 | 53
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
premature death 1 | 5
short tibia 1 | 97
thrombocytosis 1 | 27

Disease

Carcinoma 30 | 11,493
ovarian cancer 29 | 8,520
osteosarcoma 26 | 7,950
psoriasis 20 | 6,694
medulloblastoma, large-cell 19 | 6,241
glioblastoma 18 | 5,792
atypical teratoid / rhabdoid tumor 16 | 5,112
group 3 medulloblastoma 16 | 4,104
ependymoma 15 | 4,679
lung cancer 14 | 4,740
Cancer 12 | 2,499
adult high grade glioma 12 | 3,801
subependymal giant cell astrocytoma 11 | 2,287
malignant mesothelioma 10 | 3,232
Breast cancer 9 | 3,578
Epilepsy 9 | 792
Multiple myeloma 9 | 1,332
acute quadriplegic myopathy 9 | 1,158
primitive neuroectodermal tumor 9 | 3,035
Intellectual disability 8 | 1,016
Parkinson's disease 8 | 392
Seizures 8 | 596
astrocytoma 8 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
oligodendroglioma 8 | 2,850
Astrocytoma, Pilocytic 7 | 3,081
Kidney cancer 7 | 2,613
Schizophrenia 7 | 1,160
dermatomyositis 7 | 966
Amyotrophic lateral sclerosis 6 | 451
Waldenstrons macroglobulinemia 6 | 765
astrocytic glioma 6 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Autistic Disorder 5 | 364
Bipolar Disorder 5 | 666
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Pick disease 5 | 1,894
Poor school performance 5 | 645
colon cancer 5 | 1,478
group 4 medulloblastoma 5 | 1,855
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
Alzheimer's disease 4 | 658
Anemia 4 | 365
Attention deficit hyperactivity disorder 4 | 278
Autosomal recessive predisposition 4 | 1,442
Brain disease 4 | 96
Breast Neoplasms 4 | 445
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Liver Cirrhosis, Experimental 4 | 769
Mammary Neoplasms 4 | 425
Mental and motor retardation 4 | 608
Muscle hypotonia 4 | 571
Obesity 4 | 678
Rheumatoid arthritis 4 | 1,191
breast carcinoma 4 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
juvenile dermatomyositis 4 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
Asthma 3 | 385
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Fragile X syndrome 3 | 34
Hypoplastic mandible condyle 3 | 275
Impaired cognition 3 | 96
Infertility 3 | 188
Male infertility 3 | 206
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Muscular atrophy 3 | 71
Optic Atrophy 3 | 242
Polycystic ovary syndrome 3 | 360
Renal Cell Carcinoma 3 | 214
Stomach Neoplasms 3 | 300
Substance-Related Disorders 3 | 115
Toxic encephalopathy 3 | 141
Treacher Collins syndrome 3 | 27
ductal carcinoma in situ 3 | 1,745
interstitial cystitis 3 | 2,312
non primary Sjogren syndrome sicca 3 | 891
pancreatic cancer 3 | 2,398
spina bifida 3 | 1,074
tuberculosis and treatment for 6 months 3 | 409
Chronic obstructive pulmonary disease 2 | 184
Cognition Disorders 2 | 32
Heart disease 2 | 306
Hemoglobin low 2 | 124
Hepatomegaly 2 | 285
Hypothyroidism 2 | 122
Kidney disease 2 | 430
Type 2 diabetes mellitus 2 | 272

Tissue

Endocrine System 53 | 18,159
Female tissues 51 | 17,400
Nervous System 51 | 16,725
Skin and soft tissues 51 | 17,230
Blood and immune system 50 | 16,909
Digestive Tract 50 | 17,369
Liver and Pancreas 50 | 16,750
Male tissues 50 | 17,142
Respiratory system 50 | 16,393
Urinary Tract 49 | 16,678
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 39 | 12,091
Enzyme 6 | 4,145
Kinase 5 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408

GO Process

regulation of translation 53 | 53
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAP kinase-interacting serine/threonine-protein kinase 1 MKNK1 Tchem Kinase -1.71576 46.7 408
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
La-related protein 6 LARP6 Tbio Non-IDG -1.42450 28.5 86
Translational activator of cytochrome c oxidase 1 TACO1 Tdark Enzyme -0.64509 4.57 123
Treacle protein TCOF1 Tbio Non-IDG -3.44117 2743.5 131
ATP-dependent RNA helicase DDX25 DDX25 Tbio Enzyme -1.23468 21.8 47
Translation initiation factor eIF-2B subunit delta EIF2B4 Tbio Non-IDG -1.06082 11.3 145
MAP kinase-interacting serine/threonine-protein kinase 2 MKNK2 Tchem Kinase -1.32729 19.5 234
60S ribosomal protein L10 RPL10 Tbio Non-IDG -0.94919 8.10 191
Protein LSM14 homolog A LSM14A Tbio Non-IDG -1.13869 16.0 122