Development Level

Tbio 15 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal allantois morphology 1 | 8
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eyelid morphology 1 | 7
abnormal forebrain development 1 | 20
abnormal head size 1 | 6
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal left-right axis patte... 1 | 2
abnormal limb bud morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal placement of pupils 1 | 6
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
corneal opacity 1 | 32
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 12
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Cancer 13 | 2,499
Carcinoma 13 | 11,493
ovarian cancer 13 | 8,520
osteosarcoma 11 | 7,950
glioblastoma 9 | 5,792
psoriasis 9 | 6,694
Breast cancer 8 | 3,578
pancreatic cancer 8 | 2,398
tuberculosis 8 | 2,010
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
group 3 medulloblastoma 6 | 4,104
lung cancer 6 | 4,740
lung carcinoma 6 | 2,843
medulloblastoma, large-cell 6 | 6,241
primary pancreatic ductal adenocarcinoma 6 | 1,109
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
ependymoma 5 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Craniofacial Abnormalities 4 | 151
Epilepsy 4 | 792
Inflammatory bowel disease 4 | 151
Kidney disease 4 | 430
Orbital separation excessive 4 | 244
Pulmonary Fibrosis 4 | 106
Seizures 4 | 596
Ureteral obstruction 4 | 33
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807
interstitial cystitis 4 | 2,312
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
Acquired scoliosis 3 | 281
Asthma 3 | 385
Colorectal Neoplasms 3 | 243
Congenital deafness 3 | 185
Curvature of spine 3 | 282
Deafness 3 | 198
Decreased projection of midface 3 | 105
Dull intelligence 3 | 645
Hearing Loss, Partial 3 | 185
Heart disease 3 | 306
Hypertension 3 | 396
Hypertensive disease 3 | 292
Hypotrophic midface 3 | 105
Intellectual disability 3 | 1,016
Liver Cirrhosis 3 | 181
Liver Cirrhosis, Experimental 3 | 769
Liver disease 3 | 237
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Midface retrusion 3 | 105
Multiple myeloma 3 | 1,332
Myopathy 3 | 185
Neoplasm Invasiveness 3 | 161
Osteoarthritis 3 | 184
Peyronie's disease 3 | 9
Pneumonia 3 | 174
Poor school performance 3 | 645
Proteinuria 3 | 144
Small head 3 | 374
Small midface 3 | 105
Vascular disease 3 | 319
Ventricular Remodeling 3 | 5
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
hearing impairment 3 | 199
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
Anemia 2 | 365
Broad flat nasal bridge 2 | 236
Coronary artery disease 2 | 268
Decreased joint mobility 2 | 53
Hemoglobin low 2 | 124
Hernia, Inguinal 2 | 89
Hypersensitivity reaction type II disease 2 | 253
Hypoalbuminemia 2 | 24
Microstomia 2 | 78
Muscular Diseases 2 | 27
Nasal bridge wide 2 | 236
Neurodegenerative disease 2 | 414
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Strabismus 2 | 270
Umbilical hernia 2 | 93
Waldenstrons macroglobulinemia 2 | 765

Tissue

Blood and immune system 18 | 16,909
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Cardiovascular System 17 | 15,192
Female tissues 17 | 17,400
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725

Target Family

Non-IDG 10 | 12,091
Transcription Factor 6 | 1,400
Enzyme 1 | 4,145
Epigenetic 1 | 242

GO Process

regulation of transforming gro... 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
E3 ubiquitin-protein ligase TRIM33 TRIM33 Tbio Epigenetic -3.10754 1197.2 297
Zinc finger E-box-binding homeobox 1 ZEB1 Tbio Transcription Factor -2.88752 659.2 460
Latent-transforming growth factor beta-binding protein 4 LTBP4 Tbio Non-IDG -1.55113 39.1 57
Transcription factor SOX-11 SOX11 Tbio Transcription Factor -2.01545 106.1 219
Zinc finger protein 703 ZNF703 Tbio Non-IDG -1.21377 18.7 190
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
Interleukin-17F IL17F Tbio Non-IDG -2.59592 347.9 586
Integrin alpha-3 ITGA3 Tchem Non-IDG -2.08360 104.1 587