Development Level

Tbio 3 | 11,651

Disease

diabetes mellitus 3 | 1,728
Carcinoma 2 | 11,493
Diabetes Mellitus, Experimental 2 | 108
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Abnormal vision 1 | 52
Abnormality of retinal pigmentation 1 | 111
Abnormality of vision 1 | 40
Amblyopia 1 | 38
Aniridia 1 | 25
Aniridia 1 1 | 5
Aniridia type 2 1 | 1
Anterior Segment Dysgenesis 5 1 | 4
Aplasia/Hypoplasia of the macula 1 | 8
Autistic Disorder 1 | 364
Axenfeld-Rieger Syndrome, Type 1 1 | 3
Axenfeld-Rieger syndrome 1 | 14
Blepharoptosis 1 | 231
Blindness 1 | 88
CATARACT, AUTOSOMAL DOMINANT 1 | 4
Clouding of corneal stroma 1 | 50
Cloudy cornea 1 | 33
Coloboma 1 | 51
Coloboma of Optic Nerve 1 | 2
Coloboma of eyelid 1 | 15
Coloboma of lens 1 | 4
Coloboma of macula 1 | 4
Coloboma of optic disc 1 | 9
Congenital aphakia 1 | 6
Congenital coloboma of iris 1 | 4
Congenital ectopic pupil 1 | 7
Congenital neurologic anomalies 1 | 20
Congenital nystagmus 1 | 26
Congenital ocular coloboma (disorder) 1 | 40
Contiguous gene syndrome 1 | 2
Corneal Opacity 1 | 53
Corneal disease 1 | 31
Corneal stromal opacities 1 | 33
Craniofacial Abnormalities 1 | 151
Deletion 11p13 1 | 3
Disorder of the optic nerve 1 | 1
Displacement of the external urethral meatus 1 | 3
Dull foveal reflex 1 | 9
Ectropion 1 | 38
Everted lower lip vermilion 1 | 54
Explosive speech 1 | 9
FOVEAL HYPOPLASIA 1 1 | 1
Foveal hypoplasia (finding) 1 | 9
Foveal hypoplasia and presenile cataract syndrome 1 | 1
Foveal hypoplasia-presenile cataract syndrome 1 | 1
Generalized hyperpigmentation 1 | 22
Gillespie syndrome 1 | 2
Hearing abnormality 1 | 12
Hereditary macular coloboma 1 | 5
Hydrophthalmos 1 | 19
Hyperglycemia 1 | 137
Hypoplasia of the optic nerve 1 | 17
Irido-corneo-trabecular dysgenesis (disorder) 1 | 10
Keratitis 1 | 62
Keratitis, hereditary 1 | 1
Keratopathy 1 | 12
Lens subluxation 1 | 12
Leukodystrophy 1 | 55
Low Vision 1 | 174
Mask-like facies 1 | 25
Melanoma 1 | 711
Microcephaly 1 | 166
Microphthalmia 1 | 76
Morning glory syndrome 1 | 1
Movement Disorders 1 | 55
Myopia 1 | 176
Neoplasm Invasiveness 1 | 161
Nephroblastoma 1 | 51
Neurodegenerative disease 1 | 414
Neutropenia 1 | 72
O'Donnell Pappas syndrome 1 | 1
Optic Nerve Hypoplasia, Bilateral 1 | 1
Optic disc abnormalities 1 | 12
Optic nerve aplasia 1 | 3
Penile hypospadias 1 | 106
Persistent hyperplastic primary vitreous 1 | 20
Peters anomaly 1 | 16
Presenile cataract 1 | 1
Protruding lower lip 1 | 54
Ptosis 1 | 48
Reduced visual acuity 1 | 63
Renal coloboma syndrome 1 | 4
Retinal Degeneration 1 | 106
Retinal Detachment 1 | 51
Retinal pigment epithelial abnormality 1 | 111
Scanning speech 1 | 9
Scleral staphyloma 1 | 1
Somatic mutation 1 | 61
Streak ovary 1 | 15
Tooth Abnormalities 1 | 69
Vaginal malformation 1 | 7
Visual Impairment 1 | 174
WAGR syndrome 1 | 10
Waardenburg's syndrome 1 | 17
atypical teratoid/rhabdoid tumor 1 | 357

Tissue

Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Nervous System 3 | 16,725
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Blood and immune system 1 | 16,909
Male tissues 1 | 17,142
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Transcription Factor 3 | 1,400

GO Process

regulation of transcription fr... 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
Homeobox protein Nkx-6.1 NKX6-1 Tbio Transcription Factor -1.86592 62.8 247
Homeobox protein Nkx-6.2 NKX6-2 Tbio Transcription Factor -2.51005 319.0 66