Development Level

Tbio 277 | 11,651
Tdark 35 | 6,593
Tchem 26 | 1,388
Tclin 7 | 612

IMPC Phenotype

preweaning lethality, complete... 25 | 979
preweaning lethality, incomple... 14 | 499
abnormal behavior 10 | 298
abnormal seminal vesicle morph... 7 | 114
enlarged heart 6 | 210
abnormal embryo size 5 | 220
decreased leukocyte cell numbe... 5 | 73
decreased lymphocyte cell numb... 5 | 83
increased circulating alkaline... 5 | 122
abnormal heart morphology 4 | 162
embryonic growth retardation 4 | 106
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
hypoactivity 4 | 132
abnormal retina morphology 3 | 71
abnormal spleen morphology 3 | 55
abnormal tooth morphology 3 | 24
cataract 3 | 92
decreased body weight 3 | 161
decreased circulating glucose ... 3 | 126
decreased erythrocyte cell num... 3 | 62
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
hyperactivity 3 | 148
increased monocyte cell number 3 | 63
increased total body fat amoun... 3 | 134
small testis 3 | 58
thrombocytopenia 3 | 56
abnormal bone structure 2 | 187
abnormal craniofacial morpholo... 2 | 33
abnormal lens morphology 2 | 81
abnormal retinal blood vessel ... 2 | 26
abnormal skin coloration 2 | 25
abnormal skin morphology 2 | 50
abnormal testis morphology 2 | 43
anophthalmia 2 | 33
corneal opacity 2 | 32
decreased IgG2b level 2 | 4
decreased caudal vertebrae num... 2 | 53
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased eosinophil cell numb... 2 | 24
decreased grip strength 2 | 116
decreased large unstained cell... 2 | 11
decreased lean body mass 2 | 135
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
enlarged spleen 2 | 41
female infertility 2 | 60
increased anti-nuclear antigen... 2 | 19
increased body temperature 2 | 9
increased bone mineral content 2 | 108
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
male infertility 2 | 123
short tibia 2 | 97
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal epididymis morphology 1 | 42
abnormal hair growth 1 | 10
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal vertebrae morphology 1 | 18
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased circulating bilirubi... 1 | 19
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hydrometra 1 | 53
increased blood uric acid leve... 1 | 5
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
long tibia 1 | 25
microphthalmia 1 | 26
prenatal lethality 1 | 28
small kidney 1 | 16
small spleen 1 | 19
syndactyly 1 | 23
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 219 | 11,493
ovarian cancer 194 | 8,520
osteosarcoma 168 | 7,950
psoriasis 158 | 6,694
medulloblastoma, large-cell 139 | 6,241
glioblastoma 128 | 5,792
atypical teratoid / rhabdoid tumor 111 | 5,112
lung cancer 109 | 4,740
group 3 medulloblastoma 100 | 4,104
malignant mesothelioma 89 | 3,232
Breast cancer 88 | 3,578
Cancer 88 | 2,499
ependymoma 76 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 69 | 3,291
adult high grade glioma 67 | 3,801
primitive neuroectodermal tumor 66 | 3,035
invasive ductal carcinoma 61 | 2,951
oligodendroglioma 60 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 59 | 2,989
Kidney cancer 57 | 2,613
non-small cell lung cancer 56 | 2,890
lung adenocarcinoma 55 | 2,716
astrocytic glioma 50 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 50 | 2,955
subependymal giant cell astrocytoma 49 | 2,287
pancreatic cancer 47 | 2,398
lung carcinoma 46 | 2,843
Multiple myeloma 45 | 1,332
tuberculosis 45 | 2,010
Astrocytoma, Pilocytic 44 | 3,081
interstitial cystitis 44 | 2,312
diabetes mellitus 42 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 41 | 1,962
ulcerative colitis 40 | 1,819
Pick disease 39 | 1,894
group 4 medulloblastoma 39 | 1,855
juvenile dermatomyositis 38 | 1,187
Rheumatoid arthritis 37 | 1,191
pituitary cancer 37 | 1,972
astrocytoma 36 | 1,146
dermatomyositis 35 | 966
acute quadriplegic myopathy 33 | 1,158
colon cancer 33 | 1,478
cystic fibrosis 33 | 1,696
ductal carcinoma in situ 33 | 1,745
Intellectual disability 32 | 1,016
breast carcinoma 32 | 1,638
adrenocortical carcinoma 30 | 1,428
pediatric high grade glioma 30 | 1,064
Obesity 28 | 678
primary pancreatic ductal adenocarcinoma 28 | 1,109
Schizophrenia 24 | 1,160
spina bifida 24 | 1,074
Autosomal recessive predisposition 23 | 1,442
Dull intelligence 23 | 645
Low intelligence 23 | 645
Mental Retardation 23 | 645
Mental deficiency 23 | 645
Poor school performance 23 | 645
medulloblastoma 23 | 720
nasopharyngeal carcinoma 23 | 1,058
Waldenstrons macroglobulinemia 22 | 765
primary Sjogren syndrome 22 | 735
Atopic dermatitis 21 | 952
Bipolar Disorder 21 | 666
Breast Neoplasms 20 | 445
Liver Cirrhosis, Experimental 20 | 769
acute myeloid leukemia 20 | 783
Cognitive delay 19 | 608
Endometriosis 19 | 540
Global developmental delay 19 | 608
Mental and motor retardation 19 | 608
Short stature 19 | 531
active Crohn's disease 19 | 922
cutaneous lupus erythematosus 19 | 1,057
Epilepsy 18 | 792
Seizures 18 | 596
Stomach Neoplasms 18 | 300
Mammary Neoplasms 17 | 425
Prostatic Neoplasms 17 | 495
aldosterone-producing adenoma 17 | 665
Lung Neoplasms 16 | 232
Alzheimer's disease 15 | 658
Down syndrome 15 | 499
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 510
pancreatic carcinoma 15 | 562
Adenocarcinoma 14 | 122
Broad flat nasal bridge 14 | 236
Liver cancer 14 | 604
Nasal bridge wide 14 | 236
Carcinoma, Hepatocellular 13 | 228
Cleft Palate 13 | 271
Cryptorchidism 13 | 296
Fetal Growth Retardation 13 | 189
Infant, Small for Gestational Age 13 | 176
Intrauterine retardation 13 | 176
Liver carcinoma 13 | 240
Muscle hypotonia 13 | 571
Small head 13 | 374
progressive supranuclear palsy 13 | 676

Tissue

Endocrine System 333 | 18,159
Digestive Tract 325 | 17,369
Skin and soft tissues 323 | 17,230
Female tissues 322 | 17,400
Male tissues 320 | 17,142
Liver and Pancreas 313 | 16,750
Blood and immune system 312 | 16,909
Nervous System 309 | 16,725
Urinary Tract 308 | 16,678
Respiratory system 306 | 16,393
Cardiovascular System 293 | 15,192

Target Family

Transcription Factor 155 | 1,400
Non-IDG 106 | 12,091
Enzyme 39 | 4,145
Epigenetic 19 | 242
Kinase 9 | 634
Nuclear Receptor 6 | 48
TF/Epigenetic 6 | 38
Transporter 3 | 473
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

regulation of transcription fr... 345 | 345
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ETS-related transcription factor Elf-2 ELF2 Tbio Transcription Factor -2.04794 106.4 92
Teashirt homolog 2 TSHZ2 Tbio Non-IDG -0.01649 0.78 90
snRNA-activating protein complex subunit 4 SNAPC4 Tbio Transcription Factor -0.99715 10.0 160
Nuclear factor erythroid 2-related factor 1 NFE2L1 Tbio Transcription Factor -1.57346 40.9 157
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L TAF6L Tdark Enzyme 0.55 0.23 173
Runt-related transcription factor 3 RUNX3 Tbio Transcription Factor -2.71721 536.2 438
Cbp/p300-interacting transactivator 4 CITED4 Tbio Non-IDG -1.07712 14.3 100
Glucocorticoid modulatory element-binding protein 1 GMEB1 Tbio Transcription Factor -0.75841 7.65 104
Ubiquitin carboxyl-terminal hydrolase 16 USP16 Tbio Enzyme -0.67094 5.97 248