Development Level

Tbio 574 | 11,651
Tdark 475 | 6,593
Tchem 76 | 1,388
Tclin 10 | 612

Collection

Kinase: IDG Consortium (Target... 5 | 125
RFA-RM-18-021 5 | 328
Kinase: IDG Consortium (Comple... 3 | 37

IMPC Phenotype

preweaning lethality, complete... 70 | 979
preweaning lethality, incomple... 30 | 499
embryonic lethality prior to t... 25 | 278
embryonic lethality prior to o... 21 | 239
abnormal embryo size 18 | 220
abnormal behavior 13 | 298
decreased lean body mass 11 | 135
decreased total body fat amoun... 11 | 207
increased lean body mass 10 | 172
increased startle reflex 10 | 112
increased total body fat amoun... 10 | 134
abnormal bone structure 9 | 187
decreased body weight 9 | 161
decreased grip strength 9 | 116
decreased vertical activity 9 | 208
decreased circulating serum al... 8 | 82
enlarged heart 8 | 210
hypoactivity 8 | 132
abnormal heart morphology 7 | 162
hyperactivity 7 | 148
increased circulating alkaline... 7 | 122
increased or absent threshold ... 7 | 101
male infertility 7 | 123
abnormal eye morphology 6 | 68
decreased mean corpuscular vol... 6 | 79
embryonic growth retardation 6 | 106
impaired glucose tolerance 6 | 75
improved glucose tolerance 6 | 79
increased bone mineral content 6 | 108
increased mean corpuscular hem... 6 | 96
abnormal gait 5 | 69
abnormal neural tube closure 5 | 46
abnormal seminal vesicle morph... 5 | 114
cataract 5 | 92
decreased circulating choleste... 5 | 93
decreased circulating total pr... 5 | 49
decreased erythrocyte cell num... 5 | 62
decreased fasted circulating g... 5 | 65
increased bone mineral density 5 | 72
prenatal lethality prior to he... 5 | 87
short tibia 5 | 97
small superior vagus ganglion 5 | 74
small testis 5 | 58
abnormal forebrain development 4 | 20
decreased body length 4 | 101
decreased bone mineral density 4 | 126
decreased caudal vertebrae num... 4 | 53
decreased circulating alanine ... 4 | 47
decreased circulating triglyce... 4 | 79
decreased neutrophil cell numb... 4 | 42
decreased prepulse inhibition 4 | 82
edema 4 | 59
increased circulating triglyce... 4 | 42
pale yolk sac 4 | 25
abnormal kidney morphology 3 | 65
abnormal lens morphology 3 | 81
abnormal midbrain development 3 | 20
abnormal retina morphology 3 | 71
abnormal testis morphology 3 | 43
abnormal tooth morphology 3 | 24
decreased bone mineral content 3 | 151
decreased circulating HDL chol... 3 | 68
decreased circulating alkaline... 3 | 46
decreased circulating amylase ... 3 | 28
decreased circulating fructosa... 3 | 30
decreased circulating glucose ... 3 | 126
decreased circulating insulin ... 3 | 76
decreased heart left ventricle... 3 | 28
decreased mean platelet volume 3 | 25
enlarged spleen 3 | 41
hydrometra 3 | 53
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased circulating creatini... 3 | 38
increased fasted circulating g... 3 | 76
increased hemoglobin content 3 | 45
increased mean corpuscular hem... 3 | 36
increased mean platelet volume 3 | 45
pallor 3 | 34
prolonged QRS complex duration 3 | 8
thin ventricular wall 3 | 24
vertebral transformation 3 | 12
abnormal behavioral response t... 2 | 66
abnormal cranium morphology 2 | 36
abnormal lung morphology 2 | 26
abnormal retinal vasculature m... 2 | 27
abnormal sleep behavior 2 | 70
corneal opacity 2 | 32
decreased circulating LDL chol... 2 | 38
decreased circulating calcium ... 2 | 36
increased body length 2 | 32
increased circulating aspartat... 2 | 15
increased circulating serum al... 2 | 22
increased circulating sodium l... 2 | 71
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased prepulse inhibition 2 | 32
long tibia 2 | 25
tremors 2 | 39
vertebral fusion 2 | 23

Disease

Carcinoma 791 | 11,493
osteosarcoma 534 | 7,950
ovarian cancer 493 | 8,520
medulloblastoma, large-cell 351 | 6,241
glioblastoma 317 | 5,792
psoriasis 306 | 6,694
group 3 medulloblastoma 296 | 4,104
atypical teratoid / rhabdoid tumor 281 | 5,112
lung cancer 275 | 4,740
ependymoma 225 | 4,679
Kidney cancer 195 | 2,613
primitive neuroectodermal tumor 191 | 3,035
malignant mesothelioma 187 | 3,232
Breast cancer 184 | 3,578
adult high grade glioma 170 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 161 | 3,291
oligodendroglioma 154 | 2,850
Cancer 150 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 145 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 136 | 2,955
astrocytic glioma 132 | 2,597
group 4 medulloblastoma 127 | 1,855
Astrocytoma, Pilocytic 114 | 3,081
Pick disease 101 | 1,894
invasive ductal carcinoma 101 | 2,951
lung carcinoma 98 | 2,843
pancreatic cancer 94 | 2,398
subependymal giant cell astrocytoma 93 | 2,287
tuberculosis 91 | 2,010
non-small cell lung cancer 90 | 2,890
adrenocortical carcinoma 88 | 1,428
interstitial cystitis 88 | 2,312
lung adenocarcinoma 84 | 2,716
pituitary cancer 80 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 78 | 1,962
spina bifida 75 | 1,074
diabetes mellitus 73 | 1,728
Multiple myeloma 72 | 1,332
astrocytoma 72 | 1,146
Rheumatoid arthritis 68 | 1,191
cystic fibrosis 68 | 1,696
juvenile dermatomyositis 68 | 1,187
acute quadriplegic myopathy 66 | 1,158
pediatric high grade glioma 66 | 1,064
breast carcinoma 62 | 1,638
colon cancer 60 | 1,478
acute myeloid leukemia 57 | 783
ductal carcinoma in situ 55 | 1,745
ulcerative colitis 54 | 1,819
Intellectual disability 53 | 1,016
Schizophrenia 52 | 1,160
non primary Sjogren syndrome sicca 50 | 891
dermatomyositis 48 | 966
Waldenstrons macroglobulinemia 46 | 765
hepatocellular carcinoma 44 | 547
primary pancreatic ductal adenocarcinoma 43 | 1,109
medulloblastoma 42 | 720
tuberculosis and treatment for 6 months 41 | 409
Obesity 38 | 678
aldosterone-producing adenoma 38 | 665
Breast Neoplasms 36 | 445
Mammary Neoplasms 36 | 425
active Crohn's disease 36 | 922
progressive supranuclear palsy 36 | 676
Short stature 35 | 531
cutaneous lupus erythematosus 34 | 1,057
nasopharyngeal carcinoma 34 | 1,058
primary Sjogren syndrome 34 | 735
gastric cancer 33 | 459
Liver cancer 32 | 604
Epilepsy 31 | 792
Prostatic Neoplasms 31 | 495
active ulcerative colitis 31 | 764
sonic hedgehog group medulloblastoma 31 | 467
Dull intelligence 30 | 645
Low intelligence 30 | 645
Mental Retardation 30 | 645
Mental deficiency 30 | 645
Poor school performance 30 | 645
pancreatic carcinoma 30 | 562
Alzheimer's disease 29 | 658
Amyotrophic lateral sclerosis 29 | 451
Autosomal recessive predisposition 29 | 1,442
Cognitive delay 29 | 608
Global developmental delay 29 | 608
Melanoma 29 | 711
Mental and motor retardation 29 | 608
Muscle hypotonia 29 | 571
Bipolar Disorder 28 | 666
Polycystic ovary syndrome 28 | 360
Atopic dermatitis 27 | 952
Seizures 27 | 596
gastric carcinoma 27 | 807
Acquired metabolic disease 25 | 336
Orbital separation excessive 25 | 244
autosomal dominant Emery-Dreifuss muscular dystrophy 25 | 510
Broad flat nasal bridge 24 | 236
Nasal bridge wide 24 | 236
Strabismus 24 | 270
atypical teratoid/rhabdoid tumor 24 | 357

Tissue

Endocrine System 1,077 | 18,159
Skin and soft tissues 1,041 | 17,230
Female tissues 1,039 | 17,400
Digestive Tract 1,037 | 17,369
Male tissues 1,032 | 17,142
Nervous System 1,026 | 16,725
Blood and immune system 1,024 | 16,909
Urinary Tract 1,013 | 16,678
Liver and Pancreas 1,008 | 16,750
Respiratory system 1,002 | 16,393
Cardiovascular System 976 | 15,192

Target Family

Transcription Factor 600 | 1,400
Non-IDG 348 | 12,091
Epigenetic 64 | 242
Enzyme 59 | 4,145
Kinase 31 | 634
TF/Epigenetic 14 | 38
Nuclear Receptor 12 | 48
GPCR 3 | 408
Transporter 3 | 473
oGPCR 1 | 421

GO Process

regulation of transcription, D... 1,135 | 1,135
transcription, DNA-templated 1,742 | 1,742
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Olfactory receptor 7D2 OR7D2 Tdark oGPCR 0.00000 2
Zinc finger protein 236 ZNF236 Tbio Transcription Factor -0.40816 2.56 30
Zinc finger homeobox protein 2 ZFHX2 Tdark Transcription Factor -0.50515 3.13 28
INO80 complex subunit B INO80B Tbio Non-IDG -1.16370 15.1 53
Zinc finger protein 561 ZNF561 Tdark Transcription Factor 0.00000 36
Zinc finger protein 808 ZNF808 Tdark Transcription Factor 0.00000 1.00 0
Lamina-associated polypeptide 2, isoform alpha TMPO Tbio Non-IDG -2.11834 246.0 283
Serine/threonine-protein kinase MAK MAK Tchem Kinase -1.20155 15.2 266
Arginine-fifty homeobox ARGFX Tdark Transcription Factor -0.14354 1.60 94