Development Level

Tbio 2 | 11,445
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

medulloblastoma, large-cell 3 | 6,241
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Carcinoma 2 | 11,493
Epilepsy 2 | 792
Schizophrenia 2 | 1,160
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
subependymal giant cell astrocytoma 2 | 2,287
Abnormal behavior 1 | 52
Absent speech 1 | 43
Bipolar Disorder 1 | 666
Brain hypomyelination 1 | 11
Burst suppression on EEG 1 | 1
Cerebellar Ataxia 1 | 304
Cerebral atrophy 1 | 178
Choroideremia 1 | 16
Cognitive delay 1 | 608
Degenerative brain disorder 1 | 100
Developmental regression 1 | 95
Early infantile epileptic encephalopathy with suppression bursts 1 | 10
Early myoclonic encephalopathy 1 | 15
Electroencephalogram abnormal 1 | 101
Epilepsies, Myoclonic 1 | 32
Epilepsy characterized by intractable complex partial seizures 1 | 28
Epileptic Encephalopathy, Early Infantile, 4 1 | 1
Epileptic Encephalopathy, Early Infantile, 6 1 | 8
Epileptic encephalopathy 1 | 26
Febrile Convulsions 1 | 14
Focal Clonic Seizures 1 | 9
Generalized myoclonic seizures 1 | 30
Global developmental delay 1 | 608
Global developmental delay, severe 1 | 47
Griscelli syndrome 1 | 24
Highly variable severity 1 | 157
Hypertonic seizures 1 | 8
Hypomyelinating leukodystrophy 6 1 | 26
Hypoplasia of corpus callosum 1 | 90
Hypsarrhythmia 1 | 25
Impaired horizontal smooth pursuit 1 | 6
Infantile Severe Myoclonic Epilepsy 1 | 8
Infantile encephalopathy 1 | 3
Intellectual disability 1 | 1,016
Kidney cancer 1 | 2,613
Lennox-Gastaut syndrome 1 | 34
Loss of developmental milestones 1 | 95
Mental and motor retardation 1 | 608
Mental deterioration in childhood 1 | 95
Migraine Prevention 1 | 23
Muscle hypotonia 1 | 571
Myoclonic Epilepsies, Progressive 1 | 44
Neonatal onset 1 | 21
Neurodevelopmental Disorders 1 | 70
Neurodevelopmental regression 1 | 95
Obtundation status 1 | 7
Photosensitivity of skin 1 | 51
Pick disease 1 | 1,894
Psychomotor regression 1 | 95
Psychomotor regression beginning in infancy 1 | 95
Psychomotor regression in infants 1 | 95
Psychomotor regression, progressive 1 | 95
Retinitis pigmentosa 13 1 | 11
Salaam Seizures 1 | 2
Severe mental retardation (I.Q. 20-34) 1 | 99
Severe psychomotor retardation 1 | 47
Simple partial seizure 1 | 26
Spastic Paraplegia 1 | 42
Spastic Quadriplegia 1 | 42
Status Epilepticus 1 | 98
Supratentorial atrophy 1 | 94
Tonic - clonic seizures 1 | 44
Tonic-clonic epilepsy 1 | 47
Tremor 1 | 113
Variable expressivity 1 | 157
Warburg micro syndrome 1 | 18
West Syndrome 1 | 28
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
atypical teratoid/rhabdoid tumor 1 | 357
colon cancer 1 | 1,478
ductal carcinoma in situ 1 | 1,745
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
invasive ductal carcinoma 1 | 2,951
lung cancer 1 | 4,740
malignant mesothelioma 1 | 3,232
medulloblastoma 1 | 720
non-small cell lung cancer 1 | 2,890
nonverbal 1 | 43
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
primitive neuroectodermal tumor 1 | 3,035

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 1 | 4,145
Ion Channel 1 | 344
Non-IDG 1 | 12,091

GO Process

regulation of synaptic vesicle... 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamate receptor ionotropic, kainate 5 GRIK5 Tclin Ion Channel -2.11616 127.3 179
Syntaxin-binding protein 1 STXBP1 Tbio Non-IDG -2.30714 221.0 351
Ras-related protein Rab-3A RAB3A Tbio Enzyme -2.29258 206.6 236