Development Level

Tbio 20 | 11,445
Tchem 7 | 1,598
Tclin 4 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal behavior 2 | 298
edema 2 | 59
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal limb morphology 1 | 13
abnormal locomotor behavior 1 | 24
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
hemorrhage 1 | 23
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased circulating triglyce... 1 | 42
increased or absent threshold ... 1 | 101
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
respiratory system phenotype 1 | 2
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 21 | 11,493
glioblastoma 19 | 5,792
adult high grade glioma 18 | 3,801
atypical teratoid / rhabdoid tumor 18 | 5,112
ependymoma 18 | 4,679
Astrocytoma, Pilocytic 15 | 3,081
medulloblastoma, large-cell 15 | 6,241
astrocytic glioma 14 | 2,597
oligodendroglioma 14 | 2,850
osteosarcoma 14 | 7,950
ovarian cancer 13 | 8,520
Schizophrenia 11 | 1,160
primitive neuroectodermal tumor 11 | 3,035
psoriasis 11 | 6,694
Breast cancer 10 | 3,578
lung cancer 10 | 4,740
group 3 medulloblastoma 9 | 4,104
malignant mesothelioma 9 | 3,232
Kidney cancer 7 | 2,613
Pick disease 7 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
Bipolar Disorder 6 | 666
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung adenocarcinoma 6 | 2,716
tuberculosis 6 | 2,010
Autistic Disorder 5 | 364
Cancer 5 | 2,499
group 4 medulloblastoma 5 | 1,855
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
Depressive disorder 4 | 409
Epilepsy 4 | 792
Intellectual disability 4 | 1,016
Parkinson's disease 4 | 392
Seizures 4 | 596
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Atherosclerosis 3 | 291
Autism spectrum disorder 3 | 101
Cognitive delay 3 | 608
Dementia 3 | 175
Global developmental delay 3 | 608
Hypotension 3 | 82
Liver Cirrhosis, Experimental 3 | 769
Mental and motor retardation 3 | 608
Mood Disorders 3 | 184
Motor delay 3 | 147
Neurodegenerative disease 3 | 414
No development of motor milestones 3 | 147
Osteoporosis 3 | 363
Rheumatoid arthritis 3 | 1,191
Substance Withdrawal Syndrome 3 | 55
Vascular disease 3 | 319
active ulcerative colitis 3 | 764
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
gastric cancer 3 | 459
medulloblastoma 3 | 720
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Allergic hypersensitivity disease 2 | 126
Allergic rhinitis 2 | 94
Alzheimer Disease 2 | 83
Anteverted nostril 2 | 191
Arthritis 2 | 290
Arthritis, Juvenile 2 | 126
Arthrogryposis 2 | 54
Atopic dermatitis 2 | 952
Attention deficit hyperactivity disorder 2 | 278
Cerebrovascular disease 2 | 238
Cognition Disorders 2 | 32
Diarrhea 2 | 253
Gastroesophageal reflux disease 2 | 110
Heart conduction disease 2 | 83
Heart disease 2 | 306
Hyperalgesia 2 | 83
Isolated cases 2 | 72
Juvenile arthritis 2 | 126
Mental Depression 2 | 333
Osteoarthritis 2 | 184
Short nose 2 | 132
Small nose 2 | 132
Toxic encephalopathy 2 | 141
active Crohn's disease 2 | 922
dentatorubral-pallidoluysian atrophy 2 | 21
fibroadenoma 2 | 559
hepatocellular carcinoma 2 | 547
nephrosclerosis 2 | 333
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Skin and soft tissues 31 | 17,230
Nervous System 30 | 16,725
Blood and immune system 29 | 16,909
Male tissues 29 | 17,142
Urinary Tract 29 | 16,678
Cardiovascular System 28 | 15,192
Respiratory system 28 | 16,393

Target Family

Non-IDG 16 | 12,091
GPCR 4 | 408
Enzyme 3 | 4,145
Kinase 3 | 634
Transcription Factor 3 | 1,400
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

GO Process

regulation of synaptic plastic... 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tbio Non-IDG -0.56258 5.05 40
Ras/Rap GTPase-activating protein SynGAP SYNGAP1 Tbio Enzyme -1.91757 81.2 178
Nuclear factor of activated T-cells, cytoplasmic 4 NFATC4 Tbio Transcription Factor -1.93766 88.3 358
Rap guanine nucleotide exchange factor 2 RAPGEF2 Tbio Non-IDG -1.41107 29.0 79
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Eukaryotic translation initiation factor 4E-binding protein 2 EIF4EBP2 Tbio Non-IDG -1.55776 33.4 189
Histamine H2 receptor HRH2 Tclin GPCR -3.21267 1595.1 244
Contactin-4 CNTN4 Tbio Non-IDG -1.54832 35.6 117
Cytoplasmic polyadenylation element-binding protein 3 CPEB3 Tbio Non-IDG -1.34679 21.2 88
Neuronal PAS domain-containing protein 4 NPAS4 Tbio Transcription Factor -1.87450 80.6 112