Development Level

Tbio 12 | 11,445
Tchem 9 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal heart morphology 2 | 162
enlarged heart 2 | 210
increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal whole-body plethysmog... 1 | 4
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cellular hemoglobin ... 1 | 1
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
macrophthalmia 1 | 2
prolonged PR interval 1 | 15
thrombocytopenia 1 | 56

Disease

Carcinoma 20 | 11,493
Night Blindness 12 | 101
Difficulties with night vision 11 | 87
Retinitis Pigmentosa 11 | 226
psoriasis 11 | 6,694
Abnormality of retinal pigmentation 10 | 111
Autosomal recessive predisposition 10 | 1,442
Electroretinogram abnormal 10 | 95
Photodysphoria 10 | 121
Photophobia 10 | 121
Retinal pigment epithelial abnormality 10 | 111
Blind Vision 9 | 111
Blindness, Legal 9 | 110
Cataract 9 | 297
Dull intelligence 9 | 645
Intellectual disability 9 | 1,016
Keratoconus 9 | 113
Lens Opacities 9 | 231
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Nystagmus 9 | 317
Poor school performance 9 | 645
Sensorineural Hearing Loss (disorder) 9 | 284
osteosarcoma 9 | 7,950
Abnormality of the retinal vasculature 8 | 59
Anteverted nostril 8 | 191
Atypical scarring of skin 8 | 62
Broad flat nasal bridge 8 | 236
Conductive hearing loss 8 | 123
Congenital anomaly of testis 8 | 52
Congenital hypoplasia of penis 8 | 176
Glaucoma 8 | 239
Hyperinsulinism 8 | 133
Hypogonadism 8 | 173
Nasal bridge wide 8 | 236
Night blindness, progressive 8 | 51
Obesity 8 | 678
Ophthalmoplegia 8 | 106
Optic Atrophy 8 | 242
Retinal Degeneration 8 | 106
Cone dystrophy 7 | 71
Fundus dystrophy 7 | 83
Leber congenital amaurosis 6 | 69
Reduced visual acuity 6 | 63
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
ovarian cancer 6 | 8,520
primitive neuroectodermal tumor 6 | 3,035
Abnormality of macular pigmentation 5 | 16
Blindness 5 | 88
Congenital stationary night blindness 5 | 29
Hypoplasia of optic disc 5 | 12
Macular pigmentary changes 5 | 16
Night blindness, congenital stationary 5 | 16
Night blindness, congenital stationary, complete 5 | 10
Night blindness, stationary 5 | 10
Oguchi disease 5 | 10
Severe myopia 5 | 22
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
oligodendroglioma 5 | 2,850
pituitary cancer 5 | 1,972
Low Vision 4 | 174
Visual Impairment 4 | 174
group 4 medulloblastoma 4 | 1,855
lung cancer 4 | 4,740
Astrocytoma, Pilocytic 3 | 3,081
Atrial Fibrillation 3 | 124
Breast cancer 3 | 3,578
Chronic heart failure 3 | 46
Decreased amplitudes on flash visual electroretinogram 3 | 13
Loss of peripheral vision 3 | 5
Multiple myeloma 3 | 1,332
Myocardial Perfusion Imaging Adjunct 3 | 25
Partial central choroid dystrophy 3 | 11
Platelet Aggregation Inhibition 3 | 22
Prevention of Cerebral Thrombosis 3 | 29
Tunnel visual field constriction 3 | 5
cone-rod dystrophy 3 | 59
ulcerative colitis 3 | 1,819
Cancer 2 | 2,499
Epilepsy 2 | 792
Hypertension 2 | 396
Rheumatoid arthritis 2 | 1,191
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
acute quadriplegic myopathy 2 | 1,158
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Endocrine System 25 | 18,159
Digestive Tract 21 | 17,369
Skin and soft tissues 21 | 17,230
Blood and immune system 20 | 16,909
Nervous System 20 | 16,725
Female tissues 19 | 17,400
Urinary Tract 19 | 16,678
Male tissues 18 | 17,142
Cardiovascular System 17 | 15,192
Liver and Pancreas 17 | 16,750
Respiratory system 16 | 16,393

Target Family

Enzyme 14 | 4,145
Kinase 5 | 634
Non-IDG 4 | 12,091
Ion Channel 2 | 344
GPCR 1 | 408

GO Process

regulation of rhodopsin mediat... 26 | 26
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinal guanylyl cyclase 1 GUCY2D Tbio Kinase -2.20658 167.7 205
Guanylyl cyclase-activating protein 3 GUCA1C Tdark Enzyme 0.02 1.10 125
Rhodopsin kinase GRK7 Tchem Kinase -1.83396 45.0 180
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha PDE6A Tclin Enzyme -1.29228 20.3 111
Methionine aminopeptidase 1 METAP1 Tchem Enzyme -1.64901 44.4 149
Retinal guanylyl cyclase 2 GUCY2F Tbio Kinase -1.00236 7.60 84
Guanylyl cyclase-activating protein 2 GUCA1B Tbio Enzyme -1.63232 42.4 122
Glycylpeptide N-tetradecanoyltransferase 2 NMT2 Tchem Enzyme -1.21261 12.8 255
G protein-coupled receptor kinase 4 GRK4 Tchem Kinase -1.71379 54.8 171
Guanylyl cyclase-activating protein 1 GUCA1A Tbio Enzyme -1.91695 89.7 135