Development Level

Tbio 12 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal snout morphology 1 | 23
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased startle reflex 1 | 75
edema 1 | 59
embryonic growth retardation 1 | 106
increased grip strength 1 | 41
increased heart weight 1 | 62
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 10 | 11,493
ovarian cancer 9 | 8,520
Breast cancer 7 | 3,578
lung cancer 7 | 4,740
medulloblastoma, large-cell 7 | 6,241
osteosarcoma 7 | 7,950
pancreatic cancer 6 | 2,398
Cancer 5 | 2,499
glioblastoma 5 | 5,792
oligodendroglioma 5 | 2,850
Neurodegenerative disease 4 | 414
adult high grade glioma 4 | 3,801
group 3 medulloblastoma 4 | 4,104
Major Depressive Disorder 3 | 301
Multiple myeloma 3 | 1,332
Rheumatoid arthritis 3 | 1,191
Unipolar Depression 3 | 250
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
non primary Sjogren syndrome sicca 3 | 891
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Alzheimer's disease 2 | 658
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Dysgerminoma 2 | 11
Gait abnormality 2 | 135
HIV Infections 2 | 102
Kidney cancer 2 | 2,613
Mammary Neoplasms 2 | 425
Nerve Degeneration 2 | 121
PARKINSON DISEASE 19, JUVENILE-ONSET 2 | 10
Parkinson Disease 2 | 64
Parkinson's disease 2 | 392
Parkinsonian Disorders 2 | 56
Prostatic Neoplasms 2 | 495
Schizophrenia 2 | 1,160
Young onset Parkinson disease 2 | 10
colon cancer 2 | 1,478
gastric cancer 2 | 459
interstitial cystitis 2 | 2,312
interstitial lung disease 2 | 298
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pancreatic carcinoma 2 | 562
subependymal giant cell astrocytoma 2 | 2,287
Acquired flat foot 1 | 72
Aortic Valve Insufficiency 1 | 40
Aortic aneurysm 1 | 38
Arachnodactyly 1 | 49
Arterial tortuosity 1 | 5
Arterial tortuosity syndrome 1 | 7
Atypical scarring of skin 1 | 62
Benign paroxysmal positional nystagmus 1 | 11
Blue sclera 1 | 32
Brain disease 1 | 96
Carcinoma, Pancreatic Ductal 1 | 20
Carcinoma, Renal Cell 1 | 124
Cardiomegaly 1 | 116
Cleft palate with cleft lip 1 | 23
Conventional (Clear Cell) Renal Cell Carcinoma 1 | 6
Ehlers-Danlos syndrome 1 | 43
Filariasis 1 | 21
Flatfoot 1 | 73
Gliosis in the substantia nigra 1 | 3
Hereditary hemorrhagic telangiectasia 1 | 13
Hypotrophic malar bone 1 | 129
Linear atrophy 1 | 15
Macular degeneration 1 | 65
Malar flattening 1 | 129
Metabolic syndrome X 1 | 52
Multiple system atrophy 1 | 29
Muscle Rigidity 1 | 49
Oral cleft 1 | 18
Ovarian Cysts 1 | 41
Ovarian Neoplasms 1 | 102
PARKINSON DISEASE, LATE-ONSET 1 | 20
Postural instability 1 | 19
Pulmonary Fibrosis 1 | 106
Renal Cell Carcinoma 1 | 214
Renal Cell Carcinoma, Nonpapillary 1 | 7
Skin Neoplasms 1 | 69
Skull malformation 1 | 38
Spinal muscular atrophy 1 | 34
Systemic scleroderma 1 | 60
Tall stature 1 | 34
Thalassemia 1 | 53
Uremia 1 | 19
Usher syndrome type 3 1 | 5

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Non-IDG 11 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634

GO Process

regulation of protein ubiquiti... 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box only protein 2 FBXO2 Tbio Non-IDG -1.36281 26.8 157
E3 ubiquitin-protein ligase RNF139 RNF139 Tbio Enzyme -1.17169 16.6 133
Heat shock 70 kDa protein 1A HSPA1B Tchem Non-IDG -3.10995 0.00000 1174
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.61862 0.00000 60
Ubiquilin-1 UBQLN1 Tbio Non-IDG -1.92650 87.0 256
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
WASH complex subunit 1 WASHC1 Tbio Non-IDG -0.28297 2.17 4
E3 ubiquitin-protein ligase SIAH2 SIAH2 Tbio Enzyme -1.80363 66.5 173
DnaJ homolog subfamily B member 2 DNAJB2 Tbio Non-IDG -1.20146 15.3 231
E3 ubiquitin-protein ligase parkin PRKN Tbio Enzyme -2.99618 1004.1 533