Development Level

Tbio 36 | 10,625
Tchem 14 | 1,890
Tdark 9 | 7,003
Tclin 4 | 602

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 6 | 633
increased mean corpuscular vol... 4 | 91
decreased T cell number 3 | 31
decreased hemoglobin content 3 | 53
embryonic lethality prior to t... 3 | 187
increased mean corpuscular hem... 3 | 93
abnormal bone structure 2 | 131
abnormal lens morphology 2 | 73
decreased CD8-positive, alpha-... 2 | 26
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased erythrocyte cell num... 2 | 43
decreased hematocrit 2 | 25
decreased leukocyte cell numbe... 2 | 54
decreased startle reflex 2 | 48
increased effector memory CD4-... 2 | 15
increased effector memory CD8-... 2 | 14
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal coat/hair pigmentatio... 1 | 54
abnormal coping response 1 | 12
abnormal ear morphology 1 | 5
abnormal gait 1 | 51
abnormal locomotor activation 1 | 26
abnormal response to tactile s... 1 | 16
abnormal seminal vesicle morph... 1 | 47
abnormal startle reflex 1 | 14
absent startle reflex 1 | 15
cataract 1 | 26
circling 1 | 1
decreased B cell number 1 | 30
decreased CD4-positive, alpha ... 1 | 19
decreased IgG1 level 1 | 4
decreased Ly6C high monocyte n... 1 | 18
decreased NK T cell number 1 | 28
decreased T-helper cell number 1 | 4
decreased alpha-beta T cell nu... 1 | 12
decreased body weight 1 | 174
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating iron lev... 1 | 25
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
decreased prepulse inhibition 1 | 52
decreased spleen weight 1 | 13
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
head bobbing 1 | 3
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased KLRG1-positive CD4-p... 1 | 3
increased Ly6C low monocyte nu... 1 | 8
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased caudal vertebrae num... 1 | 8
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 43
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean platelet volume 1 | 19
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
male infertility 1 | 62
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
straub tail 1 | 26
thrombocytopenia 1 | 46
thrombocytosis 1 | 23
tremors 1 | 34
trunk curl 1 | 15
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

ovarian cancer 34 | 8,484
Cancer 27 | 2,346
osteosarcoma 27 | 7,933
glioblastoma 26 | 5,572
medulloblastoma, large-cell 26 | 6,234
psoriasis 25 | 6,685
atypical teratoid / rhabdoid tumor 21 | 4,369
lung cancer 20 | 4,466
oligodendroglioma 17 | 2,849
pilocytic astrocytoma 16 | 3,086
malignant mesothelioma 15 | 3,162
Breast cancer 14 | 3,094
primitive neuroectodermal tumor 14 | 3,031
Multiple myeloma 13 | 1,327
pediatric high grade glioma 13 | 2,712
Carcinoma 12 | 2,147
medulloblastoma 12 | 1,524
pancreatic cancer 12 | 2,300
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
ependymoma 10 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
non-small cell lung cancer 10 | 2,798
astrocytoma 9 | 1,493
diabetes mellitus 9 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
invasive ductal carcinoma 9 | 2,950
lung adenocarcinoma 9 | 2,713
subependymal giant cell astrocytoma 9 | 2,287
Adenocarcinoma 8 | 115
Pick disease 8 | 1,893
astrocytic glioma 8 | 2,241
lung carcinoma 8 | 2,844
Parkinson's disease 7 | 364
breast carcinoma 7 | 1,614
ductal carcinoma in situ 7 | 1,745
juvenile dermatomyositis 7 | 1,189
pituitary cancer 7 | 1,972
Liver carcinoma 6 | 217
Lung Neoplasms 6 | 171
Mammary Neoplasms 6 | 410
Neurodegenerative disease 6 | 383
acute quadriplegic myopathy 6 | 1,157
adult high grade glioma 6 | 2,148
colon cancer 6 | 1,475
esophageal adenocarcinoma 6 | 737
nasopharyngeal carcinoma 6 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
sonic hedgehog group medulloblastoma 6 | 1,482
Adenoma 5 | 165
Amyotrophic Lateral Sclerosis 5 | 431
Colorectal Neoplasms 5 | 217
Intellectual disability 5 | 573
Melanoma 5 | 261
Neuroblastoma 5 | 78
Prostatic Neoplasms 5 | 471
Stomach Neoplasms 5 | 282
Vascular disease 5 | 281
adrenocortical carcinoma 5 | 1,427
gastric cancer 5 | 430
ovarian neoplasm 5 | 97
primary pancreatic ductal adenocarcinoma 5 | 1,271
ulcerative colitis 5 | 2,087
Atopic dermatitis 4 | 944
Endometriosis 4 | 535
Glioma 4 | 65
Lymphoid leukemia 4 | 69
Neoplasm Invasiveness 4 | 127
Obesity 4 | 616
Pancreatic Neoplasm 4 | 79
Reperfusion Injury 4 | 84
Squamous cell carcinoma 4 | 94
cutaneous lupus erythematosus 4 | 1,056
cystic fibrosis 4 | 1,665
dermatomyositis 4 | 933
group 3 medulloblastoma 4 | 2,254
group 4 medulloblastoma 4 | 1,875
non-small cell lung carcinoma 4 | 413
posterior fossa group A ependymoma 4 | 1,511
tuberculosis 4 | 1,557
tuberculosis and treatment for 6 months 4 | 686
Alzheimer's disease 3 | 644
Autistic Disorder 3 | 320
Bladder Neoplasm 3 | 109
Congenital disorder of glycosylation 3 | 53
Disease Progression 3 | 125
Down syndrome 3 | 548
IGA Glomerulonephritis 3 | 454
Kidney disease 3 | 396
Liver disease 3 | 219
Lymphoma 3 | 56
Neoplasm Metastasis 3 | 138
Peripheral T-cell lymphoma 3 | 24
Primary cutaneous T-cell lymphoma 3 | 24
Prostate cancer 3 | 172
Schizophrenia 3 | 501
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
interstitial cystitis 3 | 2,299
nephrosclerosis 3 | 329

Tissue

Digestive Tract 61 | 18,473
Endocrine System 61 | 18,512
Female tissues 61 | 18,647
Liver and Pancreas 61 | 18,136
Male tissues 61 | 17,969
Nervous System 61 | 18,561
Skin and soft tissues 61 | 18,115
Urinary Tract 61 | 18,444
Blood and immune system 60 | 17,995
Cardiovascular System 60 | 17,958
Respiratory system 60 | 17,484

Target Family

Non-IDG 31 | 11,971
Enzyme 18 | 4,146
Epigenetic 5 | 242
Transcription Factor 4 | 1,400
Kinase 3 | 634
GPCR 1 | 406
Transporter 1 | 473

GO Process

regulation of protein stabilit... 63 | 63
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Apolipoprotein A-II APOA2 Tbio Non-IDG -2.80284 593.9 352
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
G-protein coupled receptor 26 GPR26 Tbio GPCR -0.57545 4.04 88
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.51989 315.7 757
26S proteasome non-ATPase regulatory subunit 8 PSMD8 Tbio Enzyme -1.35900 20.6 94
Merlin NF2 Tbio Non-IDG -3.13004 1456.9 431
NACHT, LRR and PYD domains-containing protein 5 NLRP5 Tbio Non-IDG -1.31440 20.8 37
CD81 antigen CD81 Tchem Non-IDG -2.72554 534.7 551
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial QRSL1 Tbio Enzyme -1.88966 74.9 88