Development Level

Tbio 35 | 10,625
Tchem 6 | 1,890
Tdark 4 | 7,003
Tclin 1 | 602

IMPC Term

decreased body weight 2 | 174
increased body weight 2 | 42
increased leukocyte cell numbe... 2 | 37
abnormal body wall morphology 1 | 7
abnormal embryo size 1 | 112
abnormal lumbar vertebrae morp... 1 | 6
abnormal response to tactile s... 1 | 16
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
decreased blood urea nitrogen ... 1 | 31
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased fasted circulating g... 1 | 49
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased total body fat amoun... 1 | 186
enlarged spleen 1 | 26
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased circulating chloride... 1 | 43
increased circulating serum al... 1 | 25
increased or absent threshold ... 1 | 128
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
protruding tongue 1 | 1

Disease

osteosarcoma 27 | 7,933
ovarian cancer 27 | 8,484
medulloblastoma, large-cell 25 | 6,234
glioblastoma 21 | 5,572
psoriasis 20 | 6,685
atypical teratoid / rhabdoid tumor 19 | 4,369
lung cancer 15 | 4,466
Breast cancer 14 | 3,094
pilocytic astrocytoma 14 | 3,086
Cancer 12 | 2,346
lung carcinoma 12 | 2,844
primitive neuroectodermal tumor 12 | 3,031
ependymoma 11 | 2,514
astrocytic glioma 10 | 2,241
medulloblastoma 10 | 1,524
pediatric high grade glioma 10 | 2,712
astrocytoma 9 | 1,493
invasive ductal carcinoma 9 | 2,950
malignant mesothelioma 9 | 3,162
oligodendroglioma 9 | 2,849
sonic hedgehog group medulloblastoma 9 | 1,482
subependymal giant cell astrocytoma 9 | 2,287
Multiple myeloma 7 | 1,327
adult high grade glioma 7 | 2,148
group 4 medulloblastoma 7 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
non-small cell lung cancer 7 | 2,798
tuberculosis 7 | 1,557
Carcinoma 6 | 2,147
colon cancer 6 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
lung adenocarcinoma 6 | 2,713
posterior fossa group B ependymoma 6 | 1,530
Alzheimer's disease 5 | 644
Down syndrome 5 | 548
Rheumatoid Arthritis 5 | 1,160
Waldenstrons macroglobulinemia 5 | 765
active Crohn's disease 5 | 918
adrenocortical carcinoma 5 | 1,427
breast carcinoma 5 | 1,614
cystic fibrosis 5 | 1,665
diabetes mellitus 5 | 1,663
group 3 medulloblastoma 5 | 2,254
posterior fossa group A ependymoma 5 | 1,511
progressive supranuclear palsy 5 | 674
spina bifida 5 | 1,064
ulcerative colitis 5 | 2,087
Obesity 4 | 616
Pick disease 4 | 1,893
Polydactyly 4 | 93
atypical teratoid/rhabdoid tumor 4 | 1,095
dermatomyositis 4 | 933
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 832
interstitial cystitis 4 | 2,299
nasopharyngeal carcinoma 4 | 1,056
Adenoma 3 | 165
Arthritis 3 | 248
Brain disease 3 | 83
Dementia 3 | 129
Duchenne muscular dystrophy 3 | 602
Joubert syndrome 3 | 61
Meckel syndrome 3 | 48
Meckel-Gruber syndrome 3 | 15
Migraine 3 | 79
Neurodegenerative disease 3 | 383
Orofaciodigital syndrome 3 | 19
Prostatic Neoplasms 3 | 471
Squamous cell carcinoma of esophagus 3 | 82
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
cutaneous lupus erythematosus 3 | 1,056
juvenile dermatomyositis 3 | 1,189
pancreatic cancer 3 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,271
tuberculosis and treatment for 6 months 3 | 686
Acromegaly 2 | 40
Atopic dermatitis 2 | 944
Cerebrovascular disease 2 | 231
Endometriosis 2 | 535
Eye disease 2 | 55
Heart disease 2 | 279
Hypertension 2 | 287
Hypothyroidism 2 | 89
IGA Glomerulonephritis 2 | 454
Infertility 2 | 163
Kidney disease 2 | 396
Lung disease 2 | 132
Metabolic syndrome X 2 | 155
Methylmalonic acidemia 2 | 39
Pancreatic Neoplasm 2 | 79
Parkinson's disease 2 | 364
Schizophrenia 2 | 501
Toxic encephalopathy 2 | 131
Vascular disease 2 | 281
acute quadriplegic myopathy 2 | 1,157
chronic rhinosinusitis 2 | 512
pancreatic carcinoma 2 | 567

Tissue

Cardiovascular System 46 | 17,958
Digestive Tract 46 | 18,473
Endocrine System 46 | 18,512
Female tissues 46 | 18,647
Male tissues 46 | 17,969
Nervous System 46 | 18,561
Blood and immune system 45 | 17,995
Liver and Pancreas 45 | 18,136
Respiratory system 45 | 17,484
Skin and soft tissues 45 | 18,115
Urinary Tract 45 | 18,444

Target Family

Non-IDG 31 | 11,971
Enzyme 8 | 4,146
Kinase 3 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 406
Transporter 1 | 473

GO Process

regulation of protein localiza... 46 | 46
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.40555 28.2 91
Pleckstrin homology domain-containing family M member 2 PLEKHM2 Tbio Non-IDG -0.22831 2.68 56
Small ubiquitin-related modifier 1 SUMO1 Tbio Non-IDG -2.69547 474.2 685
Ras-related protein Rab-9A RAB9A Tchem Enzyme -0.85649 7.48 172
DnaJ homolog subfamily B member 6 DNAJB6 Tbio Non-IDG -1.88632 95.9 167
Peptidyl-prolyl cis-trans isomerase FKBP1A FKBP1A Tclin Enzyme -2.75744 370.6 255
E3 ubiquitin-protein ligase TRIM22 TRIM22 Tbio Enzyme -1.46578 40.5 140
DnaJ homolog subfamily B member 2 DNAJB2 Tbio Non-IDG -1.11912 15.5 197
Ribosomal L1 domain-containing protein 1 RSL1D1 Tbio Non-IDG -1.24451 20.3 112