Development Level

Tbio 6 | 10,625
Tchem 4 | 1,890
Tclin 1 | 602
Tdark 1 | 7,003

IMPC Term

preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal coping response 1 | 12
abnormal retina morphology 1 | 100
abnormal vibrissa morphology 1 | 17
absent startle reflex 1 | 15
brachydactyly 1 | 2
decreased circulating free fat... 1 | 39
decreased lean body mass 1 | 195
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
embryonic lethality prior to t... 1 | 187
hypoactivity 1 | 89
increased circulating sodium l... 1 | 71
increased or absent threshold ... 1 | 128
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 9 | 8,484
Cancer 8 | 2,346
lung cancer 7 | 4,466
atypical teratoid / rhabdoid tumor 6 | 4,369
glioblastoma 6 | 5,572
medulloblastoma, large-cell 6 | 6,234
oligodendroglioma 6 | 2,849
psoriasis 6 | 6,685
osteosarcoma 5 | 7,933
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
primitive neuroectodermal tumor 5 | 3,031
Multiple myeloma 4 | 1,327
pediatric high grade glioma 4 | 2,712
Breast cancer 3 | 3,094
Carcinoma 3 | 2,147
Endometriosis 3 | 535
HIV Infections 3 | 100
acute quadriplegic myopathy 3 | 1,157
adrenocortical carcinoma 3 | 1,427
astrocytic glioma 3 | 2,241
colon cancer 3 | 1,475
ependymoma 3 | 2,514
invasive ductal carcinoma 3 | 2,950
malignant mesothelioma 3 | 3,162
medulloblastoma 3 | 1,524
non-small cell lung cancer 3 | 2,798
pancreatic cancer 3 | 2,300
Animal Mammary Neoplasms 2 | 136
Colorectal Neoplasms 2 | 217
Influenza 2 | 142
Li-Fraumeni Syndrome 2 | 13
Mammary Neoplasms 2 | 410
Mammary Neoplasms, Experimental 2 | 150
Pick disease 2 | 1,893
Prostatic Neoplasms 2 | 471
Schizophrenia 2 | 501
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 933
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 430
group 3 medulloblastoma 2 | 2,254
hepatocellular carcinoma 2 | 532
interstitial cystitis 2 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
juvenile dermatomyositis 2 | 1,189
lung adenocarcinoma 2 | 2,713
pilocytic astrocytoma 2 | 3,086
posterior fossa group A ependymoma 2 | 1,511
sonic hedgehog group medulloblastoma 2 | 1,482
spina bifida 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 2,087
Alzheimer's disease 1 | 644
Amyotrophic Lateral Sclerosis 1 | 431
Atopic dermatitis 1 | 944
Barrett's esophagus 1 | 183
Colonic Neoplasms 1 | 126
DOID:2627 1 | 14
Diabetes Mellitus, Non-Insulin-Dependent 1 | 157
Disease Progression 1 | 125
Glaucoma 1 | 134
Hypertension 1 | 287
Hypertensive disease 1 | 193
Hypohidrotic ectodermal dysplasia 1 | 13
Leishmaniasis 1 | 49
Lipoma 1 | 19
Long QT syndrome 1 | 52
Lung Neoplasms 1 | 171
Lymphoma, Non-Hodgkin 1 | 22
Malaria 1 | 140
Male infertility 1 | 170
Malignant neoplasm of breast 1 | 63
Malignant neoplasm of esophagus 1 | 18
Malignant neoplasm of prostate 1 | 67
Melanoma 1 | 261
Necrosis 1 | 51
Neoplastic Syndromes, Hereditary 1 | 48
Netherton syndrome 1 | 14
Neuroblastoma 1 | 78
Nijmegen breakage syndrome 1 | 23
Peripheral Neuropathy 1 | 303
Prostate cancer 1 | 172
Renal Cell Carcinoma 1 | 199
Stomach Neoplasms 1 | 282
Vaccinia 1 | 37
active Crohn's disease 1 | 918
adrenocortical adenoma 1 | 134
breast carcinoma 1 | 1,614
cystic fibrosis 1 | 1,665
cystic fibrosis and chronic rhinosinusitis 1 | 213
glioblastoma multiforme 1 | 347
head and neck cancer 1 | 270
inflammatory breast cancer 1 | 404
interstitial lung disease 1 | 291
non-small cell lung carcinoma 1 | 413
pancreatic carcinoma 1 | 567
tuberculosis 1 | 1,557

Tissue

Blood and immune system 12 | 17,995
Cardiovascular System 12 | 17,958
Digestive Tract 12 | 18,473
Endocrine System 12 | 18,512
Female tissues 12 | 18,647
Liver and Pancreas 12 | 18,136
Male tissues 12 | 17,969
Nervous System 12 | 18,561
Respiratory system 12 | 17,484
Skin and soft tissues 12 | 18,115
Urinary Tract 12 | 18,444

Target Family

Enzyme 6 | 4,146
Non-IDG 5 | 11,971
Kinase 1 | 634

GO Process

regulation of protein cataboli... 12 | 12
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
E3 ubiquitin-protein ligase NEDD4-like NEDD4L Tbio Enzyme -2.45381 312.7 133
FAS-associated factor 1 FAF1 Tbio Non-IDG -1.66741 51.3 183
Ornithine decarboxylase ODC1 Tclin Enzyme -3.36592 2473.5 349
Protein FAM83D FAM83D Tbio Non-IDG -1.54654 39.4 49
Hepatocyte growth factor-regulated tyrosine kinase substrate HGS Tbio Enzyme -2.83610 704.3 332
Exportin-1 XPO1 Tbio Non-IDG -3.08394 1175.4 149
Serine/threonine-protein kinase Chk2 CHEK2 Tchem Kinase -2.96951 933.5 1234
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.33601 2084.6 341
Furin FURIN Tchem Enzyme -3.06606 1118.7 206