Development Level

Tbio 8 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal retina morphology 2 | 71
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
brachydactyly 1 | 19
decreased body length 1 | 101
decreased circulating free fat... 1 | 31
decreased circulating serum al... 1 | 82
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
hypoactivity 1 | 132
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97

Disease

Carcinoma 11 | 11,493
ovarian cancer 11 | 8,520
atypical teratoid / rhabdoid tumor 9 | 5,112
Cancer 8 | 2,499
lung cancer 8 | 4,740
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
ependymoma 6 | 4,679
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
psoriasis 6 | 6,694
group 3 medulloblastoma 5 | 4,104
osteosarcoma 5 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Multiple myeloma 4 | 1,332
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Colonic Neoplasms 3 | 142
Endometriosis 3 | 540
HIV Infections 3 | 102
Kidney cancer 3 | 2,613
Skin Neoplasms 3 | 69
acute quadriplegic myopathy 3 | 1,158
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
Animal Mammary Neoplasms 2 | 136
Breast Neoplasms 2 | 445
Colorectal Neoplasms 2 | 243
Disease of mental health 2 | 36
Encephalopathy, progressive 2 | 6
Increased risk of pancreatic cancer 2 | 9
Influenza 2 | 142
Li-Fraumeni syndrome 2 | 13
Lymphoma 2 | 81
Malignant neoplasm of pancreas 2 | 9
Malignant neoplasm of skin 2 | 15
Mammary Neoplasms 2 | 425
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Nervous System Neoplasms 2 | 8
Pancreatic Neoplasm 2 | 85
Pick disease 2 | 1,894
Progressive brain disease 2 | 6
Prostatic Neoplasms 2 | 495
Schizophrenia 2 | 1,160
Tumors of Adrenal Cortex 2 | 3
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormalities, Multiple 1 | 13
Alkaline phosphatase serum increased 1 | 29
Arts syndrome 1 | 26
Barrett's esophagus 1 | 182
Carcinoma of colon 1 | 32
Carcinoma, Non-Small-Cell Lung 1 | 107
Celiac disease 1 | 116
Glioma 1 | 74
Hyperargininemia 1 | 8
Hypohidrotic ectodermal dysplasia 1 | 15
Idiopathic scoliosis 1 | 31
Lipoma 1 | 32
Long QT syndrome 1 | 39
Lymphoid leukemia 1 | 160
Lytic lesion 1 | 32
Malignant neoplasm of prostate 1 | 11
Malignant tumor of prostate 1 | 26
Meningioma 1 | 41
Nijmegen breakage syndrome 1 | 24
Osteochondrosis 1 | 17
Papilloma 1 | 44
Periventricular nodular heterotopia 1 | 30
Precancerous Conditions 1 | 80
Renal Cell Carcinoma 1 | 214
Sarcoma 1 | 62
Vaccinia 1 | 36
inflammatory breast cancer 1 | 286
interstitial lung disease 1 | 298
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Enzyme 6 | 4,145
Non-IDG 5 | 12,091
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

regulation of protein cataboli... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
FAS-associated factor 1 FAF1 Tbio Non-IDG -1.71858 56.5 209
Protein FAM83D FAM83D Tbio Non-IDG -1.64896 45.1 59
Serine/threonine-protein kinase Chk2 CHEK2 Tchem Kinase -3.00304 978.7 1374
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
E3 ubiquitin-protein ligase NEDD4-like NEDD4L Tbio Enzyme -2.52486 353.9 144
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.41690 2313.9 1252
Aryl hydrocarbon receptor nuclear translocator-like protein 1 ARNTL Tbio Transcription Factor -2.83548 672.9 330
Hepatocyte growth factor-regulated tyrosine kinase substrate HGS Tbio Enzyme -2.76643 560.1 379
Furin FURIN Tchem Enzyme -3.10213 1183.5 260
Exportin-1 XPO1 Tbio Non-IDG -3.14385 1273.6 200