Development Level

Tbio 37 | 10,625
Tchem 25 | 1,890
Tclin 16 | 602

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
embryonic lethality prior to t... 4 | 187
abnormal embryo size 3 | 112
decreased bone mineral content 3 | 157
decreased kidney weight 3 | 7
decreased circulating creatini... 2 | 31
enlarged heart 2 | 111
impaired pupillary reflex 2 | 14
abnormal body wall morphology 1 | 7
abnormal bone structure 1 | 131
abnormal cornea morphology 1 | 24
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal motor learning 1 | 4
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal vasculature m... 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal tail morphology 1 | 17
absent startle reflex 1 | 15
cataract 1 | 26
cleft palate 1 | 6
corneal opacity 1 | 25
decreased T cell number 1 | 31
decreased body weight 1 | 174
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
embryonic lethality prior to o... 1 | 148
enlarged lymph nodes 1 | 27
immune system phenotype 1 | 17
impaired righting response 1 | 19
increased CD4-positive, alpha ... 1 | 15
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating triglyce... 1 | 24
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased respiratory quotient 1 | 12
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
mydriasis 1 | 9
narrow eye opening 1 | 15
no spontaneous movement 1 | 1

Disease

Cancer 50 | 2,346
osteosarcoma 42 | 7,933
lung cancer 35 | 4,466
medulloblastoma, large-cell 35 | 6,234
psoriasis 35 | 6,685
ovarian cancer 33 | 8,484
glioblastoma 32 | 5,572
interstitial cystitis 31 | 2,299
Breast cancer 28 | 3,094
invasive ductal carcinoma 26 | 2,950
malignant mesothelioma 24 | 3,162
atypical teratoid / rhabdoid tumor 23 | 4,369
non-small cell lung cancer 23 | 2,798
ulcerative colitis 23 | 2,087
Carcinoma 21 | 2,147
lung adenocarcinoma 21 | 2,713
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
lung carcinoma 20 | 2,844
cystic fibrosis 18 | 1,665
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
oligodendroglioma 18 | 2,849
pilocytic astrocytoma 18 | 3,086
cutaneous lupus erythematosus 16 | 1,056
diabetes mellitus 16 | 1,663
ductal carcinoma in situ 16 | 1,745
pancreatic cancer 16 | 2,300
pituitary cancer 16 | 1,972
breast carcinoma 15 | 1,614
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
pediatric high grade glioma 15 | 2,712
Mammary Neoplasms 14 | 410
ependymoma 14 | 2,514
subependymal giant cell astrocytoma 13 | 2,287
Prostatic Neoplasms 12 | 471
astrocytic glioma 12 | 2,241
group 3 medulloblastoma 12 | 2,254
medulloblastoma 12 | 1,524
Cleft palate 11 | 125
Lung Neoplasms 11 | 171
Rheumatoid Arthritis 11 | 1,160
colon cancer 11 | 1,475
group 4 medulloblastoma 11 | 1,875
primary Sjogren syndrome 11 | 789
tuberculosis 11 | 1,557
Cleft Lip 9 | 91
Kidney disease 9 | 396
Liver carcinoma 9 | 217
Renal Cell Carcinoma 9 | 199
Stomach Neoplasms 9 | 282
primary pancreatic ductal adenocarcinoma 9 | 1,271
primitive neuroectodermal tumor 9 | 3,031
spina bifida 9 | 1,064
Asthma 8 | 349
Down syndrome 8 | 548
Pick disease 8 | 1,893
Schizophrenia 8 | 501
fibroadenoma 8 | 557
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
posterior fossa group B ependymoma 8 | 1,530
Alzheimer's disease 7 | 644
Atopic dermatitis 7 | 944
Craniosynostosis 7 | 47
Hamman-Rich syndrome 7 | 35
Heart disease 7 | 279
adrenocortical carcinoma 7 | 1,427
atypical teratoid/rhabdoid tumor 7 | 1,095
gastric carcinoma 7 | 832
juvenile dermatomyositis 7 | 1,189
nasopharyngeal carcinoma 7 | 1,056
ovarian neoplasm 7 | 97
posterior fossa group A ependymoma 7 | 1,511
Achondroplasia 6 | 20
Adenocarcinoma 6 | 115
Craniofacial Abnormalities 6 | 147
Kidney cancer 6 | 118
LADD syndrome 6 | 9
Lung disease 6 | 132
Neoplasm Invasiveness 6 | 127
Obesity 6 | 616
Parkinson's disease 6 | 364
Pulmonary Fibrosis 6 | 66
Sarcoma of soft tissue 6 | 11
Squamous cell carcinoma 6 | 94
Vascular disease 6 | 281
Waldenstrons macroglobulinemia 6 | 765
adult high grade glioma 6 | 2,148
astrocytoma 6 | 1,493
chronic rhinosinusitis 6 | 512
mucosa-associated lymphoid tissue lymphoma 6 | 480
non-small cell lung carcinoma 6 | 413
pancreatic carcinoma 6 | 567
Adenoma 5 | 165
Arthritis 5 | 248
Atherosclerosis 5 | 275
Disease Progression 5 | 125
Eosinophilia 5 | 65
Mastocytosis 5 | 27
Peripheral Neuropathy 5 | 303
Polycystic Ovary Syndrome 5 | 332
esophageal adenocarcinoma 5 | 737

Tissue

Endocrine System 78 | 18,512
Female tissues 78 | 18,647
Nervous System 78 | 18,561
Digestive Tract 77 | 18,473
Liver and Pancreas 77 | 18,136
Skin and soft tissues 77 | 18,115
Urinary Tract 77 | 18,444
Blood and immune system 76 | 17,995
Cardiovascular System 76 | 17,958
Male tissues 75 | 17,969
Respiratory system 72 | 17,484

Target Family

Non-IDG 43 | 11,971
Kinase 26 | 634
Enzyme 9 | 4,146

GO Process

regulation of phosphatidylinos... 78 | 78
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein phosphatase non-receptor type 13 PTPN13 Tchem Enzyme -2.20613 177.9 120
Fibroblast growth factor 5 FGF5 Tbio Non-IDG -2.00731 99.9 143
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.48996 301.3 641
Beta-klotho KLB Tbio Enzyme -1.89423 69.9 47
Deleted in autism protein 1 C3orf58 Tbio Non-IDG -1.14690 16.5 72
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.51373 345.1 271
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.07424 1194.2 1600
Fibroblast growth factor 2 FGF2 Tchem Non-IDG -3.97848 10115.4 658
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -2.99303 933.5 424
Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 Tbio Non-IDG -2.42637 343.3 423