Development Level

Tchem 2 | 1,388

IMPC Phenotype

abnormal heart left ventricle ... 1 | 16
abnormal seminal vesicle morph... 1 | 114
decreased lymphocyte cell numb... 1 | 83
hydrometra 1 | 53
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Atherosclerosis 2 | 291
Cancer 2 | 2,499
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
Actinic keratosis 1 | 21
Acute kidney injury 1 | 70
African trypanosomiasis 1 | 5
Alcohol abuse 1 | 50
Alzheimer's disease 1 | 658
Arthritis 1 | 290
Asthma 1 | 385
Autoimmune Diseases 1 | 67
Bipolar Disorder 1 | 666
Brain Neoplasms 1 | 33
Brain infarction 1 | 22
Breast Neoplasms 1 | 445
Carcinoma 1 | 11,493
Ceroid lipofuscinosis, neuronal 1, infantile 1 | 10
Chronic obstructive pulmonary disease 1 | 184
Colitis 1 | 54
Demyelinating Diseases 1 | 7
Diabetes Mellitus, Experimental 1 | 108
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Diabetic retinopathy 1 | 56
Encephalomyelitis, Autoimmune, Experimental 1 | 8
Esophageal Neoplasms 1 | 69
Experimental Autoimmune Encephalomyelitis 1 | 7
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Fibrosis 1 | 44
Genomic Instability 1 | 5
Glucose Intolerance 1 | 19
HIV Infections 1 | 102
Heart Diseases 1 | 43
Heart disease 1 | 306
Heart failure 1 | 162
Huntington's disease 1 | 76
Hyperglycemia 1 | 137
Hypertension 1 | 396
Hypertensive disease 1 | 292
Hypertrophy 1 | 17
Impaired glucose tolerance 1 | 28
Insulin Resistance 1 | 72
Kidney disease 1 | 430
Liver Cirrhosis, Experimental 1 | 769
Lung Injury 1 | 20
Mammary Neoplasms 1 | 425
Metabolic Syndrome 1 | 20
Metabolic syndrome X 1 | 52
Mood Disorders 1 | 184
Myocardial Reperfusion Injury 1 | 37
Neoplasm Metastasis 1 | 168
Nerve Degeneration 1 | 121
Neurodegenerative Diseases 1 | 38
Neurodegenerative Disorders 1 | 79
Non-alcoholic Fatty Liver Disease 1 | 42
Obesity 1 | 678
Paralysed 1 | 42
Paralysis 1 | 9
Parkinson's disease 1 | 392
Pneumonia 1 | 174
Pneumonia, Pneumococcal 1 | 6
Prostatic Neoplasms 1 | 495
Psychoses, Drug 1 | 9
Retinal Diseases 1 | 55
Schizophrenia 1 | 1,160
Scleroderma, Systemic 1 | 13
Shared Paranoid Disorder 1 | 5
Streptococcal pneumonia 1 | 6
Systemic scleroderma 1 | 60
Thrombosis 1 | 46
Toxic encephalopathy 1 | 141
Vascular disease 1 | 319
Wallerian Degeneration 1 | 4
adrenocortical carcinoma 1 | 1,428
diabetes mellitus 1 | 1,728
uncontrolled asthma 1 | 56

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 1 | 4,145
Epigenetic 1 | 242

GO Process

regulation of peroxisome proli... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NAD-dependent protein deacetylase sirtuin-1 SIRT1 Tchem Epigenetic -3.50639 3413.7 733
Arachidonate 15-lipoxygenase ALOX15 Tchem Enzyme -2.43772 277.6 185