Development Level

Tbio 13 | 11,445
Tchem 8 | 1,598
Tclin 3 | 613

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
anophthalmia 1 | 33
decreased circulating choleste... 1 | 93
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hyperactivity 1 | 148
increased grip strength 1 | 41
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased vertical activity 1 | 24
male infertility 1 | 123
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

ovarian cancer 15 | 8,520
psoriasis 14 | 6,694
osteosarcoma 13 | 7,950
Cancer 12 | 2,499
glioblastoma 12 | 5,792
lung cancer 11 | 4,740
Carcinoma 10 | 11,493
medulloblastoma, large-cell 10 | 6,241
Breast cancer 9 | 3,578
adult high grade glioma 9 | 3,801
ependymoma 9 | 4,679
invasive ductal carcinoma 9 | 2,951
Heart disease 8 | 306
Hypertension 8 | 396
astrocytic glioma 8 | 2,597
Autosomal recessive predisposition 7 | 1,442
Breast Neoplasms 7 | 445
Mammary Neoplasms 7 | 425
Schizophrenia 7 | 1,160
atypical teratoid / rhabdoid tumor 7 | 5,112
breast carcinoma 7 | 1,638
diabetes mellitus 7 | 1,728
lung adenocarcinoma 7 | 2,716
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
ulcerative colitis 7 | 1,819
Alzheimer's disease 6 | 658
Astrocytoma, Pilocytic 6 | 3,081
Hypertensive disease 6 | 292
Liver Cirrhosis, Experimental 6 | 769
Rheumatoid arthritis 6 | 1,191
Seizures 6 | 596
ductal carcinoma in situ 6 | 1,745
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
Bipolar Disorder 5 | 666
Epilepsy 5 | 792
Kidney cancer 5 | 2,613
Kidney disease 5 | 430
Lung disease 5 | 142
Major Depressive Disorder 5 | 301
Multiple myeloma 5 | 1,332
Prostatic Neoplasms 5 | 495
Stomach Neoplasms 5 | 300
interstitial cystitis 5 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Arthritis 4 | 290
Atherosclerosis 4 | 291
Cardiomegaly 4 | 116
Cerebrovascular disease 4 | 238
Cognitive delay 4 | 608
Coronary artery disease 4 | 268
Depressive disorder 4 | 409
Diabetes Mellitus, Experimental 4 | 108
Global developmental delay 4 | 608
Hyperglycemia 4 | 137
Hyperinsulinism 4 | 133
Infantile onset 4 | 238
Insulin Resistance 4 | 72
Lipid metabolism disorder 4 | 114
Mental Depression 4 | 333
Mental and motor retardation 4 | 608
Mood Disorders 4 | 184
Obesity 4 | 678
Pick disease 4 | 1,894
Unipolar Depression 4 | 250
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
malignant mesothelioma 4 | 3,232
pancreatic carcinoma 4 | 562
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
Alcoholic Intoxication, Chronic 3 | 289
Alzheimer Disease 3 | 83
Anemia 3 | 365
Colonic Neoplasms 3 | 142
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Dystonia 3 | 164
Dystonic disease 3 | 106
Highly variable severity 3 | 157
Inflammation 3 | 120
Lung Neoplasms 3 | 232
Myocardial Ischemia 3 | 169
Myopathy 3 | 185
Osteoporosis 3 | 363
Parkinson's disease 3 | 392
Toxic encephalopathy 3 | 141
Tremor 3 | 113
Variable expressivity 3 | 157
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
pituitary cancer 3 | 1,972

Tissue

Blood and immune system 24 | 16,909
Cardiovascular System 24 | 15,192
Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Nervous System 24 | 16,725
Respiratory system 24 | 16,393
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678

Target Family

Enzyme 11 | 4,145
Non-IDG 9 | 12,091
Kinase 4 | 634

GO Process

regulation of nitric-oxide syn... 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 DDAH1 Tchem Enzyme -2.13636 144.4 205
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.80099 639.3 247
Nostrin NOSTRIN Tbio Non-IDG -1.10079 14.1 128
Palmitoyltransferase ZDHHC21 ZDHHC21 Tbio Enzyme -0.65091 4.34 94
Cytoglobin CYGB Tbio Non-IDG -3.10582 1269.7 202
Sepiapterin reductase SPR Tbio Enzyme -1.58814 36.9 174
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein NOS1AP Tbio Enzyme -2.13262 142.6 159
Acyl-protein thioesterase 1 LYPLA1 Tchem Enzyme -1.83454 68.8 214
Nitric oxide synthase, endothelial NOS3 Tchem Enzyme -3.96497 9525.3 1195