Development Level

Tbio 11 | 11,178
Tchem 9 | 1,885
Tclin 6 | 612
Tdark 1 | 6,569

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal seminal vesicle morph... 2 | 114
hyperactivity 2 | 148
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal lip morphology 1 | 2
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent testes 1 | 6
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating iron lev... 1 | 32
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
female infertility 1 | 60
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased startle reflex 1 | 112
male infertility 1 | 123
microphthalmia 1 | 26
premature death 1 | 5
short tibia 1 | 97
shortened RR interval 1 | 17

Disease

Carcinoma 20 | 11,192
medulloblastoma, large-cell 14 | 6,086
ovarian cancer 14 | 8,297
osteosarcoma 12 | 7,766
Cancer 11 | 2,388
glioblastoma 11 | 5,635
lung cancer 10 | 4,607
psoriasis 10 | 6,514
atypical teratoid / rhabdoid tumor 9 | 4,971
malignant mesothelioma 9 | 3,135
Astrocytoma, Pilocytic 8 | 3,006
Breast cancer 8 | 3,469
Depressive disorder 8 | 401
Obesity 8 | 655
adult high grade glioma 8 | 3,701
Autosomal recessive predisposition 7 | 1,407
group 4 medulloblastoma 7 | 1,806
invasive ductal carcinoma 7 | 2,867
oligodendroglioma 7 | 2,768
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,911
Breast Neoplasms 6 | 423
Kidney cancer 6 | 2,548
Mammary Neoplasms 6 | 403
Schizophrenia 6 | 1,136
Short stature 6 | 514
diabetes mellitus 6 | 1,683
ductal carcinoma in situ 6 | 1,686
lung adenocarcinoma 6 | 2,627
pituitary cancer 6 | 1,915
Adenocarcinoma 5 | 116
Anemia 5 | 353
Autistic Disorder 5 | 358
Bipolar Disorder 5 | 646
Hypoplastic mandible condyle 5 | 273
Intellectual disability 5 | 998
Late tooth eruption 5 | 59
Mammary Neoplasms, Experimental 5 | 147
Mandibular hypoplasia 5 | 273
Mental Depression 5 | 325
Micrognathism 5 | 273
breast carcinoma 5 | 1,589
ependymoma 5 | 4,559
group 3 medulloblastoma 5 | 4,002
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,902
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,204
Acquired scoliosis 4 | 274
Animal Mammary Neoplasms 4 | 130
Brachydactyly 4 | 154
Byzanthine arch palate 4 | 194
Curvature of spine 4 | 275
Dull intelligence 4 | 634
Epilepsy 4 | 775
Heart disease 4 | 288
High forehead 4 | 101
Hypertension 4 | 372
Hyperthyroidism 4 | 52
Hypothyroidism 4 | 115
Low intelligence 4 | 634
Mammary Neoplasms, Animal 4 | 130
Melanocytic nevus 4 | 43
Mental Retardation 4 | 634
Mental deficiency 4 | 634
Orbital separation excessive 4 | 240
Parkinson's disease 4 | 378
Poor school performance 4 | 634
Prostatic Neoplasms 4 | 472
Seizures 4 | 584
Stomach Neoplasms 4 | 287
Tall forehead 4 | 101
adrenocortical carcinoma 4 | 1,385
astrocytic glioma 4 | 2,530
astrocytoma 4 | 1,113
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,872
lung carcinoma 4 | 2,755
non-small cell lung cancer 4 | 2,799
posterior fossa group A ependymoma 4 | 456
subependymal giant cell astrocytoma 4 | 2,230
Acromegaly 3 | 48
Adenoma 3 | 159
Arthritis 3 | 276
Atherosclerosis 3 | 276
Atopic dermatitis 3 | 915
Attention deficit hyperactivity disorder 3 | 272
Bilateral fifth finger clinodactyly 3 | 109
Curvature of little finger 3 | 109
Delayed bone age 3 | 132
Down syndrome 3 | 480
Endometriosis 3 | 521
Hypoglycemia 3 | 146
Kidney disease 3 | 411
Melanoma 3 | 689
Myocardial Ischemia 3 | 162
Neurodegenerative disease 3 | 402
Polycystic ovary syndrome 3 | 348
Type 2 diabetes mellitus 3 | 268
Ventricular Septal Defects 3 | 113
active ulcerative colitis 3 | 736
juvenile dermatomyositis 3 | 1,147
nasopharyngeal carcinoma 3 | 1,024
pancreatic cancer 3 | 2,322

Tissue

Endocrine System 27 | 18,159
Digestive Tract 26 | 17,369
Female tissues 26 | 17,400
Skin and soft tissues 26 | 17,230
Male tissues 25 | 17,142
Respiratory system 25 | 16,393
Urinary Tract 25 | 16,678
Cardiovascular System 24 | 15,192
Liver and Pancreas 24 | 16,750
Nervous System 24 | 16,725
Blood and immune system 23 | 16,909

Target Family

Enzyme 9 | 4,145
Non-IDG 8 | 12,091
Kinase 3 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344

GO Process

regulation of multicellular or... 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
AFG3-like protein 2 AFG3L2 Tbio Enzyme -1.58716 39.9 164
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
C-type natriuretic peptide NPPC Tbio Non-IDG -2.91034 740.1 175
D(3) dopamine receptor DRD3 Tclin GPCR -2.51699 312.3 189
Attractin ATRN Tbio Non-IDG -2.61000 386.6 172
Signal transducer and activator of transcription 5B STAT5B Tchem Transcription Factor -3.02570 950.5 620
Prolactin PRL Tbio Non-IDG -3.98498 10147.6 1281
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 Tclin Ion Channel -1.59683 37.4 101
Glycerol-3-phosphate acyltransferase 4 GPAT4 Tbio Enzyme -1.61972 41.3 205