Development Level

Tbio 12 | 11,651
Tchem 8 | 1,388
Tclin 6 | 612
Tdark 1 | 6,593

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal seminal vesicle morph... 2 | 114
hyperactivity 2 | 148
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal lip morphology 1 | 2
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent testes 1 | 6
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating iron lev... 1 | 32
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
female infertility 1 | 60
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased startle reflex 1 | 112
male infertility 1 | 123
microphthalmia 1 | 26
premature death 1 | 5
short tibia 1 | 97
shortened RR interval 1 | 17

Disease

Carcinoma 22 | 11,493
ovarian cancer 16 | 8,520
medulloblastoma, large-cell 15 | 6,241
osteosarcoma 13 | 7,950
Cancer 12 | 2,499
glioblastoma 11 | 5,792
psoriasis 11 | 6,694
atypical teratoid / rhabdoid tumor 10 | 5,112
lung cancer 10 | 4,740
malignant mesothelioma 10 | 3,232
Breast cancer 9 | 3,578
Depressive disorder 9 | 409
oligodendroglioma 9 | 2,850
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
Obesity 8 | 678
adult high grade glioma 8 | 3,801
Schizophrenia 7 | 1,160
group 4 medulloblastoma 7 | 1,855
invasive ductal carcinoma 7 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Bipolar Disorder 6 | 666
Breast Neoplasms 6 | 445
Intellectual disability 6 | 1,016
Kidney cancer 6 | 2,613
Mammary Neoplasms 6 | 425
Mental Depression 6 | 333
Short stature 6 | 531
astrocytic glioma 6 | 2,597
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
lung adenocarcinoma 6 | 2,716
pituitary cancer 6 | 1,972
Adenocarcinoma 5 | 122
Anemia 5 | 365
Autistic Disorder 5 | 364
Dull intelligence 5 | 645
Epilepsy 5 | 792
Hypoplastic mandible condyle 5 | 275
Late tooth eruption 5 | 61
Low intelligence 5 | 645
Mammary Neoplasms, Experimental 5 | 154
Mandibular hypoplasia 5 | 275
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Micrognathism 5 | 275
Neurodegenerative disease 5 | 414
Parkinson's disease 5 | 392
Poor school performance 5 | 645
Seizures 5 | 596
breast carcinoma 5 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung carcinoma 5 | 2,843
Acquired scoliosis 4 | 281
Animal Mammary Neoplasms 4 | 136
Blepharoptosis 4 | 231
Brachydactyly 4 | 156
Byzanthine arch palate 4 | 194
Cognitive delay 4 | 608
Curvature of spine 4 | 282
Down syndrome 4 | 499
Global developmental delay 4 | 608
Heart disease 4 | 306
High forehead 4 | 102
Hypertension 4 | 396
Hyperthyroidism 4 | 53
Hypothyroidism 4 | 122
Liver Cirrhosis, Experimental 4 | 769
Mammary Neoplasms, Animal 4 | 136
Melanocytic nevus 4 | 43
Mental and motor retardation 4 | 608
Nerve Degeneration 4 | 121
Orbital separation excessive 4 | 244
Polycystic ovary syndrome 4 | 360
Prostatic Neoplasms 4 | 495
Stomach Neoplasms 4 | 300
Tall forehead 4 | 102
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
non-small cell lung cancer 4 | 2,890
posterior fossa group A ependymoma 4 | 468
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 658
Arthritis 3 | 290
Atherosclerosis 3 | 291
Atopic dermatitis 3 | 952
Bilateral fifth finger clinodactyly 3 | 110
Curvature of little finger 3 | 110
Delayed bone age 3 | 136
Endometriosis 3 | 540
Myocardial Ischemia 3 | 169
Type 2 diabetes mellitus 3 | 272
Ventricular Septal Defects 3 | 119
nasopharyngeal carcinoma 3 | 1,058

Tissue

Endocrine System 27 | 18,159
Digestive Tract 26 | 17,369
Female tissues 26 | 17,400
Skin and soft tissues 26 | 17,230
Male tissues 25 | 17,142
Respiratory system 25 | 16,393
Urinary Tract 25 | 16,678
Cardiovascular System 24 | 15,192
Liver and Pancreas 24 | 16,750
Nervous System 24 | 16,725
Blood and immune system 23 | 16,909

Target Family

Enzyme 9 | 4,145
Non-IDG 8 | 12,091
Kinase 3 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344

GO Process

regulation of multicellular or... 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Glycerol-3-phosphate acyltransferase 4 GPAT4 Tbio Enzyme -1.61972 41.3 205
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.11032 1400.0 1077
Prolactin PRL Tbio Non-IDG -3.98498 10147.6 1281
Signal transducer and activator of transcription 5B STAT5B Tchem Transcription Factor -3.02570 950.5 620
Superoxide dismutase [Cu-Zn] SOD1 Tbio Enzyme -3.30643 1972.1 1103
Cyclin-dependent kinase 4 CDK4 Tclin Kinase -3.24878 1546.3 803
Neuropeptide Y receptor type 1 NPY1R Tchem GPCR -2.41095 180.3 301
Tankyrase-2 TNKS2 Tchem Enzyme -1.95640 86.0 160