Development Level

Tbio 9 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased mean corpuscular hem... 2 | 96
preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
decreased fasted circulating g... 1 | 65
enlarged heart 1 | 210
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
short tibia 1 | 97

Disease

Carcinoma 6 | 11,493
ovarian cancer 6 | 8,520
osteosarcoma 5 | 7,950
lung cancer 4 | 4,740
Autosomal recessive predisposition 3 | 1,442
Big calvaria 3 | 147
Brain hypomyelination 3 | 11
Central nervous system demyelination 3 | 28
Cessation of head growth 3 | 5
Childhood Ataxia with Central Nervous System Hypomyelinization 3 | 6
Decreased serum progesterone 3 | 5
Delusions 3 | 11
Developmental regression 3 | 95
Dysarthria 3 | 192
Epilepsy 3 | 792
Forgetful 3 | 40
Gait, Unsteady 3 | 29
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Lethargy 3 | 77
Leukodystrophy 3 | 55
Leukoencephalopathies 3 | 29
Leukoencephalopathy with vanishing white matter 3 | 20
Loss of developmental milestones 3 | 95
Memory Loss 3 | 40
Memory impairment 3 | 40
Mental deterioration in childhood 3 | 95
Mood swings 3 | 77
Muscle Spasticity 3 | 195
Muscle hypotonia 3 | 571
Neurodevelopmental regression 3 | 95
OVARIOLEUKODYSTROPHY 3 | 6
Optic Atrophy 3 | 242
Personality change 3 | 23
Premature Menopause 3 | 31
Primary gonadal insufficiency 3 | 9
Psychomotor regression 3 | 95
Psychomotor regression beginning in infancy 3 | 95
Psychomotor regression in infants 3 | 95
Psychomotor regression, progressive 3 | 95
Secondary physiologic amenorrhea 3 | 32
Seizures 3 | 596
Vanishing White Matter Leukodystrophy with Ovarian Failure 3 | 5
glioblastoma 3 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
Adenocarcinoma of lung 2 | 142
Astrocytoma, Pilocytic 2 | 3,081
Pick disease 2 | 1,894
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
fibroadenoma 2 | 559
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
nasopharyngeal carcinoma 2 | 1,058
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
spina bifida 2 | 1,074
Adenocarcinoma Of Esophagus 1 | 14
Adenocarcinoma of lung (disorder) 1 | 60
Amenorrhea 1 | 58
Amyotrophic lateral sclerosis 1 | 451
Breast cancer 1 | 3,578
Celiac disease 1 | 116
Diabetic Nephropathies 1 | 37
Diabetic Nephropathy 1 | 34
Disease Models, Animal 1 | 155
Disease of mental health 1 | 36
Disseminated intravascular coagulation 1 | 38
Duchenne muscular dystrophy 1 | 601
Frontotemporal dementia 1 | 51
Heart conduction disease 1 | 83
Kidney cancer 1 | 2,613
Kidney disease 1 | 430
Leukemia 1 | 104
Long QT syndrome 1 | 39
Long QT syndrome 1 1 | 20
Nonsyndromic deafness 1 | 142
Ovarian dysfunction 1 | 18
Premature ovarian failure 1 | 65
Romano-Ward Syndrome 1 | 12
Status Epilepticus 1 | 98
Stevens-Johnson syndrome 1 | 92
Sudden infant death syndrome 1 | 32
Syncope 1 | 22
Torsades de Pointes 1 | 8
Ventricular Fibrillation 1 | 17
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
colon cancer 1 | 1,478
diabetes mellitus 1 | 1,728
lung adenocarcinoma 1 | 2,716
non-small cell lung cancer 1 | 2,890
subependymal giant cell astrocytoma 1 | 2,287
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192
Nervous System 9 | 16,725

Target Family

Non-IDG 8 | 12,091
Enzyme 2 | 4,145

GO Process

regulation of molecular functi... 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-1-syntrophin SNTA1 Tbio Non-IDG -1.49227 31.4 254
Translation initiation factor eIF-2B subunit delta EIF2B4 Tbio Non-IDG -1.06082 11.3 145
Epidermal growth factor receptor kinase substrate 8-like protein 2 EPS8L2 Tbio Enzyme -0.25549 1.86 195
WD repeat-containing protein 41 WDR41 Tbio Non-IDG -0.28817 1.20 77
Ragulator complex protein LAMTOR4 LAMTOR4 Tdark Non-IDG -0.19564 1.23 34
Translation initiation factor eIF-2B subunit beta EIF2B2 Tbio Non-IDG -1.51608 32.2 137
Ragulator complex protein LAMTOR1 LAMTOR1 Tbio Non-IDG -1.09203 13.9 36
Engulfment and cell motility protein 1 ELMO1 Tbio Non-IDG -1.62242 45.4 178
Translation initiation factor eIF-2B subunit alpha EIF2B1 Tbio Non-IDG -1.43466 25.7 100
Epidermal growth factor receptor kinase substrate 8-like protein 1 EPS8L1 Tbio Enzyme -0.13830 1.63 120