Development Level

Tbio 15 | 11,445
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
increased circulating creatini... 2 | 38
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating total pr... 1 | 49
increased circulating chloride... 1 | 41
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 15 | 11,493
ovarian cancer 10 | 8,520
Breast cancer 9 | 3,578
lung cancer 9 | 4,740
group 3 medulloblastoma 8 | 4,104
osteosarcoma 8 | 7,950
glioblastoma 7 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
medulloblastoma, large-cell 7 | 6,241
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
Kidney cancer 5 | 2,613
invasive ductal carcinoma 5 | 2,951
psoriasis 5 | 6,694
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
interstitial cystitis 4 | 2,312
Atopic dermatitis 3 | 952
Cancer 3 | 2,499
Endometriosis 3 | 540
Liver cancer 3 | 604
Pick disease 3 | 1,894
astrocytoma 3 | 1,146
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Autosomal recessive predisposition 2 | 1,442
Cardiovascular system disease 2 | 246
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Dull intelligence 2 | 645
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Muscle Spasticity 2 | 195
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
Poor school performance 2 | 645
Slow progression 2 | 89
Urinary bladder cancer 2 | 36
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 416
Acute Promyelocytic Leukemia 1 | 40
Acute cystitis 1 | 35
Amnesia 1 | 17
Apathy 1 | 16
Autosomal recessive polycystic kidney disease 1 | 41
Colon diverticulum anatomic structure 1 | 15
Decreased motor NCV 1 | 22
Diffuse large B-cell lymphoma 1 | 39
Diverticular disease of colon 1 | 15
Epithelial tumor of ovary 1 | 3
Frequent falls 1 | 12
Hyperplasia of foramen magnum 1 | 6
Hypesthesia 1 | 7
Hypophonia 1 | 7
Increased circumference of foramen magnum 1 | 6
Increased diameter of foramen magnum 1 | 6
Inflammatory myofibroblastic tumor 1 | 8
Large foramen magnum 1 | 6
Leukemia, Promyelocytic, Acute 1 | 36
Mask-like facies 1 | 25
Muscle Cramp 1 | 55
Muscle Rigidity 1 | 49
Muscle weakness of limb 1 | 21
Nystagmus, continuous pendular 1 | 14
Oculogyric crisis 1 | 4
Pain 1 | 103
Parkinsonian Disorders 1 | 56
Pendular Nystagmus 1 | 14
Polycystic liver disease 1 | 16
Pyuria 1 | 5
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Shuffling, short-stepped gait 1 | 5
Sleeplessness 1 | 16
Spinocerebellar ataxia type 1 1 | 16
Staphyloenterotoxemia 1 | 18
Striatonigral Degeneration, Infantile 1 | 4
Substance Withdrawal Syndrome 1 | 55
Thyroid cancer, papillary 1 | 14
Vocal Cord Paralysis 1 | 7
Voice Fatigue 1 | 7
cone-rod dystrophy 1 | 59

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Non-IDG 15 | 12,091
Enzyme 1 | 4,145

GO Process

regulation of mitotic spindle ... 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Targeting protein for Xklp2 TPX2 Tbio Non-IDG -2.21148 180.0 435
Nuclear pore glycoprotein p62 NUP62 Tbio Non-IDG -1.80390 62.5 241
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Transforming acidic coiled-coil-containing protein 3 TACC3 Tbio Non-IDG -1.99617 101.2 222
Guanine nucleotide-binding protein G(i) subunit alpha-1 GNAI1 Tbio Non-IDG -0.63224 3.23 220
Dynactin subunit 1 DCTN1 Tbio Non-IDG -2.05626 108.5 214
Poly [ADP-ribose] polymerase 3 PARP3 Tclin Enzyme -1.66230 41.9 193
Proline/serine-rich coiled-coil protein 1 PSRC1 Tbio Non-IDG -1.32037 23.7 165
mRNA export factor RAE1 Tbio Non-IDG -1.82005 53.7 146